CUSABIO

  • IHC image of CSB-RA155605A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

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    Anti CTNNB1 mAb (Clone 5E1)

    Catalog No.(s): CSB-RA155605A0HU, CSB-RA155605A0HU-50, CSB-RA155605A0HU-100

    Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and...

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  • Immunofluorescence staining of HepG2 Cells with CSB-RA155372A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

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    Anti SKP2 mAb (Clone 3C11)

    Catalog No.(s): CSB-RA155372A0HU, CSB-RA155372A0HU-50, CSB-RA155372A0HU-100

    Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and...

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  • Immunofluorescence staining of MCF7 Cells with CSB-RA155156A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

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    Anti INSR mAb (Clone 4B2)

    Catalog No.(s): CSB-RA155156A0HU, CSB-RA155156A0HU-50, CSB-RA155156A0HU-100

    Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling...

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  • Western Blot<br /> Positive WB detected in: Rat Brain whole cell lysate, Rat Lung whole cell lysate, Mouse Brain whole cell lysate<br /> All lanes: FGFR2 Antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 93, 87, 93, 77, 92, 89, 86, 29, 80, 93, 97, 92, 41, 80, 80, 77, 80 kDa<br /> Observed band size: 145 kDa<br />

    CusaBio

    Anti FGFR2 mAb (Clone 2E9)

    Catalog No.(s): CSB-RA154582A0HU, CSB-RA154582A0HU-50, CSB-RA154582A0HU-100

    Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development...

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  • IHC image of CSB-RA153677A0HU diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

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    Anti CYP3A4 mAb (Clone 10B10)

    Catalog No.(s): CSB-RA153677A0HU, CSB-RA153677A0HU-50, CSB-RA153677A0HU-100

    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, 293T whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate<br /> All lanes: BRD4 antibody at 1:1500<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 153, 81, 89 kDa<br /> Observed band size: 153 kDa<br />

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    Anti BRD4 mAb (Clone 1E5)

    Catalog No.(s): CSB-RA152430A0HU, CSB-RA152430A0HU-50, CSB-RA152430A0HU-100

    Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, L02 whole cell lysate, HepG2 whole cell lysate, Mouse Brain whole cell lysate, Rat Brain whole cell lysate<br /> All lanes: ROCK2 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 161 kDa<br /> Observed band size: 161 kDa<br />

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    Anti ROCK2 mAb (Clone 10E1)

    Catalog No.(s): CSB-RA152329A0HU, CSB-RA152329A0HU-50, CSB-RA152329A0HU-100

    Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, 293T whole cell lysate, Jurkat whole cell lysate, A549 whole cell lysate, HL60 whole cell lysate, MCF-7 whole cell lysate<br /> All lanes: SMC1A antibody at 1:1500<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 144 kDa<br /> Observed band size: 144 kDa<br />

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    Anti SMC1A mAb (Clone 8C11)

    Catalog No.(s): CSB-RA149196A0HU, CSB-RA149196A0HU-50, CSB-RA149196A0HU-100

    Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large...

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  • Western Blot<br /> Positive WB detected in: U87 whole cell lysate<br /> All lanes: TGM2 antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 78, 62, 39 kDa<br /> Observed band size: 78 kDa<br />

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    Anti TGM2 mAb (Clone 7E1)

    Catalog No.(s): CSB-RA147681A0HU, CSB-RA147681A0HU-50, CSB-RA147681A0HU-100

    Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Product Specifications Application WB, ELISA Reactivity Human Clonality Monoclonal (Clone No.: 70)

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  • Western Blot<br /> Positive WB detected in: HL60 whole cell lysate, 293 whole cell lysate, PC-3 whole cell lysate, K562 whole cell lysate<br /> All lanes: MIF antibody at 1:1500<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 13 kDa<br /> Observed band size: 13 kDa<br />

    CusaBio

    Anti MIF mAb (Clone 7A9)

    Catalog No.(s): CSB-RA146975A0HU, CSB-RA146975A0HU-50, CSB-RA146975A0HU-100

    Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, U-87 whole cell lysate, Mouse Brain whole cell lysate<br /> All lanes: SF3B1 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 146, 17 kDa<br /> Observed band size: 130 kDa<br />

    CusaBio

    Anti SF3B1 mAb (Clone 6C7)

    Catalog No.(s): CSB-RA102629A0HU, CSB-RA102629A0HU-50, CSB-RA102629A0HU-100

    Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it...

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    Anti YY1 mAb (Clone 3A11)

    Catalog No.(s): CSB-RA026297A0HU, CSB-RA026297A0HU-50, CSB-RA026297A0HU-100

    Please click here to view other Bone-related ProductsMultifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. Binds to the...

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  • Western Blot<br /> Positive WB detected in HepG2 whole cell lysate(treated with Calyculin A or not)<br /> All lanes Phospho-YAP1 antibody at 0.83μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 65 KDa<br /> Observed band size: 65 KDa<br />

    CusaBio

    Anti Phospho-YAP1 (S127) mAb (Clone 3F3)

    Catalog No.(s): CSB-RA026244A127phHU, CSB-RA026244A127phHU-50, CSB-RA026244A127phHU-100

    Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, 293 whole cell lysate, Jurkat whole cell lysate, HL-60 whole cell lysate, LO2 whole cell lysate, Raji whole cell lysate, Rat heart tissue, Mouse brain tissue<br /> All lanes: VDAC1 antibody at 0.7μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 31 KDa<br /> Observed band size: 31 KDa<br />

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    Anti VDAC1 mAb (Clone 3A1)

    Catalog No.(s): CSB-RA025821A0HU, CSB-RA025821A0HU-50, CSB-RA025821A0HU-100

    Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, Mouse kidney tissue<br /> All lanes: PBR antibody at 1.2μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 19, 11 KDa<br /> Observed band size: 19 KDa<br />

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    Anti TSPO mAb (Clone 23G2)

    Catalog No.(s): CSB-RA025168A0HU, CSB-RA025168A0HU-50, CSB-RA025168A0HU-100

    Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise...

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  • Western Blot<br /> Positive WB detected in 293 whole cell lysate(treated with Calyculin A or Pervanadate)<br /> All lanes Phospho-TP53 antibody at 1.28μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 53 KDa<br /> Observed band size: 53 KDa<br />

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    Anti Phospho-TP53 (T55) mAb (Clone 3C3)

    Catalog No.(s): CSB-RA024077A55phHU, CSB-RA024077A55phHU-50, CSB-RA024077A55phHU-100

    Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by...

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  • Western Blot<br /> Positive WB detected in: 293 whole cell lysate(treated with Calyculin A or not)<br /> All lanes: Phospho-TP53 antibody at 0.64&mu;g/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 53 KDa<br /> Observed band size: 53 KDa

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    Anti Phospho-TP53 (S392) mAb (Clone 3F5)

    Catalog No.(s): CSB-RA024077A392phHU, CSB-RA024077A392phHU-50, CSB-RA024077A392phHU-100

    Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by...

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  • IHC image of CSB-RA024077A33phHU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

    CusaBio

    Anti Phospho-TP53 (S33) mAb (Clone 3E7)

    Catalog No.(s): CSB-RA024077A33phHU, CSB-RA024077A33phHU-50, CSB-RA024077A33phHU-100

    Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by...

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  • Immunofluorescence staining of MCF-7 cells with CSB-RA024077A09phHU at 1:100,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).

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    Anti Phospho-TP53 (S9) mAb (Clone 2E1)

    Catalog No.(s): CSB-RA024077A09phHU, CSB-RA024077A09phHU-50, CSB-RA024077A09phHU-100

    Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by...

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  • IHC image of CSB-RA022948A0HU diluted at 1:92.5 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

    CusaBio

    Anti SUMO1 mAb (Clone 5G3)

    Catalog No.(s): CSB-RA022948A0HU, CSB-RA022948A0HU-50, CSB-RA022948A0HU-100

    Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme...

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  • Western Blot<br /> Positive WB detected in: Jurkat whole cell lysate, K562 whole cell lysate<br /> All lanes: STIP1 antibody at 0.9μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 63, 69, 60 KDa<br /> Observed band size: 63 KDa<br />

    CusaBio

    Anti STIP1 mAb (Clone 3E4)

    Catalog No.(s): CSB-RA022831A0HU, CSB-RA022831A0HU-50, CSB-RA022831A0HU-100

    Acts as a co-chaperone for HSP90AA1 (PubMed:27353360). Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90 (By similarity). Product Specifications Application WB, ELISA Reactivity Human Clonality Monoclonal (Clone No.:...

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  • Western Blot<br /> Positive WB detected in HepG2 whole cell lysate(treated with EGF or not)<br /> All lanes Phospho-STAT5A antibody at 1.025μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 90 KDa<br /> Observed band size: 90 KDa<br />

    CusaBio

    Anti Phospho-STAT5A (Y694) mAb (Clone 3F1)

    Catalog No.(s): CSB-RA022814A694phHU, CSB-RA022814A694phHU-50, CSB-RA022814A694phHU-100

    Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1,...

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  • Western Blot<br /> Positive WB detected in A549 whole cell lysate(treated with EGF or not)<br /> All lanes Phospho-STAT3 antibody at 1.88μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 98 KDa<br /> Observed band size: 98 KDa<br />

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    Anti Phospho-STAT3 (S727) mAb (Clone 2A9)

    Catalog No.(s): CSB-RA022812A727phHU, CSB-RA022812A727phHU-50, CSB-RA022812A727phHU-100

    Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed:10688651, PubMed:12359225, PubMed:12873986, PubMed:15194700, PubMed:17344214, PubMed:18242580,...

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  • Western Blot<br /> Positive WB detected in A549 whole cell lysate,Jurkat whole cell lysate(treated with EGF or Pervanadate)<br /> All lanes Phospho-STAT3 antibody at 0.925μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 88 KDa<br /> Observed band size: 88 KDa<br />

    CusaBio

    Anti Phospho-STAT3 (Tyr705) mAb (Clone 3D11)

    Catalog No.(s): CSB-RA022812A705phHU, CSB-RA022812A705phHU-50, CSB-RA022812A705phHU-100

    Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed:10688651, PubMed:12359225, PubMed:12873986, PubMed:15194700, PubMed:17344214, PubMed:18242580,...

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  • Western Blot<br /> Positive WB detected in HepG2 whole cell lysate(treated with Calyculin A or not)<br /> All lanes Phospho-STAT1 antibody at 1.065μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 87 KDa<br /> Observed band size: 87 KDa<br />

    CusaBio

    Anti Phospho-STAT1 (S727) mAb (Clone 2H10)

    Catalog No.(s): CSB-RA022810A727phHU, CSB-RA022810A727phHU-50, CSB-RA022810A727phHU-100

    Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors,...

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  • Western Blot<br /> Positive WB detected in: NIH/3T3 whole cell lysate, MCF-7 whole cell lysate<br /> All lanes: SRC antibody at 1.2μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 60, 61 KDa<br /> Observed band size: 60, 61 KDa<br />

    CusaBio

    Anti SRC mAb (Clone 21H5)

    Catalog No.(s): CSB-RA022650A0HU, CSB-RA022650A0HU-50, CSB-RA022650A0HU-100

    Please click here to view other Bone-related ProductsNon-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors,...

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  • IHC image of CSB-RA021912A129phHU diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

    CusaBio

    Anti Phospho-SNCA (S129) mAb (Clone 4G3)

    Catalog No.(s): CSB-RA021912A129phHU, CSB-RA021912A129phHU-50, CSB-RA021912A129phHU-100

    May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Product...

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  • Western Blot<br /> Positive WB detected in 293 whole cell lysate(treated with Calyculin A or not)<br /> All lanes Phospho-RPS6KB1 antibody at 0.93μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 70 KDa<br /> Observed band size: 70 KDa<br />

    CusaBio

    Anti Phospho-RPS6KB1 (T421+S424) mAb (Clone 3B6)

    Catalog No.(s): CSB-RA020470A421phHU, CSB-RA020470A421phHU-50, CSB-RA020470A421phHU-100

    Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6...

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  • IHC image of CSB-RA020468A376phHU diluted at 1:100 and staining in paraffin-embedded human bladder cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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    Anti Phospho-RPS6KA5 (S376) mAb (Clone 2F3)

    Catalog No.(s): CSB-RA020468A376phHU, CSB-RA020468A376phHU-50, CSB-RA020468A376phHU-100

    Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene...

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  • Immunofluorescence staining of Hela cells with CSB-RA020089A21phHU at 1:100,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).

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    Anti Phospho-RPA2 (T21) mAb (Clone 3B2)

    Catalog No.(s): CSB-RA020089A21phHU, CSB-RA020089A21phHU-50, CSB-RA020089A21phHU-100

    As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates...

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  • Immunofluorescence staining of K562 cells with CSB-RA019386A807phHU at 1:100,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).

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    Anti Phospho-RB1 (S807) mAb (Clone 1H3)

    Catalog No.(s): CSB-RA019386A807phHU, CSB-RA019386A807phHU-50, CSB-RA019386A807phHU-100

    Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with...

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  • IHC image of CSB-RA019386A780phHU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

    CusaBio

    Anti Phospho-RB1 (S780) mAb (Clone 2E9)

    Catalog No.(s): CSB-RA019386A780phHU, CSB-RA019386A780phHU-50, CSB-RA019386A780phHU-100

    Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with...

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  • IHC image of CSB-RA019338A0HU diluted at 1:155 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

    CusaBio

    Anti RARA mAb (Clone 4A10)

    Catalog No.(s): CSB-RA019338A0HU, CSB-RA019338A0HU-50, CSB-RA019338A0HU-100

    Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR...

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  • Western Blot<br /> Positive WB detected in Hela whole cell lysate(treated with Calyculin A or EGF)<br /> All lanes Phospho-RAF1 antibody at 1.525μg/ml<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 73 KDa<br /> Observed band size: 73 KDa<br />

    CusaBio

    Anti Phospho-RAF1 (S621) mAb (Clone 1C2)

    Catalog No.(s): CSB-RA019284A621phHU, CSB-RA019284A621phHU-50, CSB-RA019284A621phHU-100

    Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation,...

    $210.00 - $350.00
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  • Immunofluorescence staining of Hela with CSB-RA019284A43phHU at 1:100,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).

    CusaBio

    Anti Phospho-RAF1 (S43) mAb (Clone 1F7)

    Catalog No.(s): CSB-RA019284A43phHU, CSB-RA019284A43phHU-50, CSB-RA019284A43phHU-100

    Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation,...

    $210.00 - $350.00
    Choose Options