CUSABIO

  • Western Blot<br /> Positive WB detected in: K562 whole cell lysate, 293 whole cell lysate, RAW264.7 whole cell lysate<br /> All lanes: eIF4A1 Antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 40, 47 kDa<br /> Observed band size: 50 kDa<br />

    CusaBio

    Anti EIF4A1 mAb (Clone 7C3)

    Catalog No.(s): CSB-RA190088A0HU, CSB-RA190088A0HU-50, CSB-RA190088A0HU-100

    ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs...

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  • IHC image of CSB-RA188594A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti GPX4 mAb (Clone 9D4)

    Catalog No.(s): CSB-RA188594A0HU, CSB-RA188594A0HU-50, CSB-RA188594A0HU-100

    Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic...

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  • IHC image of CSB-RA188270A0HU diluted at 1:100 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti STAT3 mAb (Clone 9F10)

    Catalog No.(s): CSB-RA188270A0HU, CSB-RA188270A0HU-50, CSB-RA188270A0HU-100

    Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed:10688651, PubMed:12359225, PubMed:12873986, PubMed:15194700, PubMed:17344214, PubMed:18242580,...

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  • Western Blot<br /> Positive WB detected in: Jurkat whole cell lysate, Hela whole cell lysate, HEK293 whole cell lysate, HepG2 whole cell lysate, A375 whole cell lysate, A549 whole cell lysate, Rat Brain whole cell lysate, Mouse Brain whole cell lysate<br /> All lanes: ERK2 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 42, 37 kDa<br /> Observed band size: 42 kDa<br />

    CusaBio

    Anti MAPK1 mAb (Clone 10C7)

    Catalog No.(s): CSB-RA187762A0HU, CSB-RA187762A0HU-50, CSB-RA187762A0HU-100

    Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade...

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  • IHC image of CSB-RA187479A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti MME mAb (Clone 10G11)

    Catalog No.(s): CSB-RA187479A0HU, CSB-RA187479A0HU-50, CSB-RA187479A0HU-100

    Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a...

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  • IHC image of CSB-RA186773A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti TRPM8 mAb (Clone 2G7)

    Catalog No.(s): CSB-RA186773A0HU, CSB-RA186773A0HU-50, CSB-RA186773A0HU-100

    Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, HEK293 whole cell lysate, Ntera-2 whole cell lysate<br /> All lanes: Caspase-3 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 32 kDa<br /> Observed band size: 32, 28 kDa<br />

    CusaBio

    Anti CASP3 mAb (Clone 2B10)

    Catalog No.(s): CSB-RA182616A0HU, CSB-RA182616A0HU-50, CSB-RA182616A0HU-100

    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, U251 whole cell lysate, Rat brain tissue, Rat liver tissue<br /> All lanes: VCP antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 90 kDa<br /> Observed band size: 90 kDa<br />

    CusaBio

    Anti VCP mAb (Clone 5H12)

    Catalog No.(s): CSB-RA182227A0HU, CSB-RA182227A0HU-50, CSB-RA182227A0HU-100

    Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi...

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  • Western Blot<br /> Positive WB detected in: HepG2 whole cell lysate, U251 whole cell lysate, U87 whole cell lysate<br /> All lanes: TTF1 antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 39 kDa<br /> Observed band size: 39 kDa<br />

    CusaBio

    Anti NKX2-1 mAb (Clone 6C11)

    Catalog No.(s): CSB-RA181189A0HU, CSB-RA181189A0HU-50, CSB-RA181189A0HU-100

    Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, 293 whole cell lysate, Jurkat whole cell lysate, SH-SY5Y whole cell lysate, THP-1 whole cell lysate, PC-3 whole cell lysate, Rat brain tissue<br /> All lanes: ATF5 antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 31 kDa<br /> Observed band size: 35 kDa<br />

    CusaBio

    Anti ATF5 mAb (Clone 9D8)

    Catalog No.(s): CSB-RA180846A0HU, CSB-RA180846A0HU-50, CSB-RA180846A0HU-100

    Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus:...

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  • IHC image of CSB-RA180423A0HU diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti DDX6 mAb (Clone 6D8)

    Catalog No.(s): CSB-RA180423A0HU, CSB-RA180423A0HU-50, CSB-RA180423A0HU-100

    In the process of mRNA degradation, plays a role in mRNA decapping (PubMed:16364915). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts (PubMed:26098573). Product...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, L02 whole cell lysate<br /> All lanes: CYP1A2 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 59 kDa<br /> Observed band size: 59 kDa<br />

    CusaBio

    Anti CYP1A2 mAb (Clone 8B2)

    Catalog No.(s): CSB-RA178519A0HU, CSB-RA178519A0HU-50, CSB-RA178519A0HU-100

    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and...

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  • Western Blot<br /> Positive WB detected in: Daudi whole cell lysate<br /> All lanes: CD48 antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 28, 20 kDa<br /> Observed band size: 45 kDa<br />

    CusaBio

    Anti CD48 mAb (Clone 7E1)

    Catalog No.(s): CSB-RA178195A0HU, CSB-RA178195A0HU-50, CSB-RA178195A0HU-100

    Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. Product Specifications Application WB, ELISA Reactivity Human Clonality Monoclonal (Clone No.:...

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  • Western Blot<br /> Positive WB detected in: NIH/3T3 whole cell lysate, K562 whole cell lysate, Mouse Brain whole cell lysate<br /> All lanes: CDC42 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 22, 22 kDa<br /> Observed band size: 24 kDa<br />

    CusaBio

    Anti CDC42 mAb (Clone 3C3)

    Catalog No.(s): CSB-RA177985A0HU, CSB-RA177985A0HU-50, CSB-RA177985A0HU-100

    Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes...

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  • Western Blot<br /> Positive WB detected in: MCF-7 whole cell lysate, Rat brain tissue, Mouse brain tissue<br /> All lanes: BACE1 antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 56, 53, 52, 49, 46, 43 kDa<br /> Observed band size: 72 kDa<br />

    CusaBio

    Anti BACE1 mAb (Clone 7G3)

    Catalog No.(s): CSB-RA177574A0HU, CSB-RA177574A0HU-50, CSB-RA177574A0HU-100

    Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble...

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  • Western Blot<br /> Positive WB detected in: Raji whole cell lysate, Hela whole cell lysate, HL60 whole cell lysate, Jurkat whole cell lysate, A549 whole cell lysate<br /> All lanes: PRMT5 antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 73, 72, 54, 68, 67 kDa<br /> Observed band size: 73 kDa<br />

    CusaBio

    Anti PRMT5 mAb (Clone 2H4)

    Catalog No.(s): CSB-RA176962A0HU, CSB-RA176962A0HU-50, CSB-RA176962A0HU-100

    Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA (PubMed:10531356, PubMed:11152681, PubMed:11747828, PubMed:12411503,...

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  • Western Blot<br /> Positive WB detected in: K562 whole cell lysate, 293T whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate<br /> All lanes: Chk1 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 55, 44, 51 kDa<br /> Observed band size: 55 kDa<br />

    CusaBio

    Anti CHEK1 mAb (Clone 2F2)

    Catalog No.(s): CSB-RA176809A0HU, CSB-RA176809A0HU-50, CSB-RA176809A0HU-100

    Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed...

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  • Western Blot<br /> Positive WB detected in: K562 whole cell lysate<br /> All lanes: UAP1 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 59, 58, 59 kDa<br /> Observed band size: 59 kDa<br />

    CusaBio

    Anti UAP1 mAb (Clone 1F2)

    Catalog No.(s): CSB-RA174034A0HU, CSB-RA174034A0HU-50, CSB-RA174034A0HU-100

    Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P. Product...

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  • Western Blot<br /> Positive WB detected in: NIH/3T3 whole cell lysate, SH-SY5Y whole cell lysate, U-87 whole cell lysate<br /> All lanes: Estrogen Receptor alpha antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 67, 54, 48, 36 kDa<br /> Observed band size: 67 kDa<br />

    CusaBio

    Anti ESR1 mAb (Clone 3H8)

    Catalog No.(s): CSB-RA172909A0HU, CSB-RA172909A0HU-50, CSB-RA172909A0HU-100

    Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves...

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  • IHC image of CSB-RA171021A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti BRAF mAb (Clone 6G3)

    Catalog No.(s): CSB-RA171021A0HU, CSB-RA171021A0HU-50, CSB-RA171021A0HU-100

    Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal...

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  • Immunofluorescence staining of Hela Cells with CSB-RA170650A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

    CusaBio

    Anti RHEB mAb (Clone 7G7)

    Catalog No.(s): CSB-RA170650A0HU, CSB-RA170650A0HU-50, CSB-RA170650A0HU-100

    Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity. Product...

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  • IHC image of CSB-RA166706A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti ATM mAb (Clone 3G11)

    Catalog No.(s): CSB-RA166706A0HU, CSB-RA166706A0HU-50, CSB-RA166706A0HU-100

    Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus...

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  • Western Blot<br /> Positive WB detected in: THP-1 whole cell lysate<br /> All lanes: CD32 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 35, 36 kDa<br /> Observed band size: 45 kDa<br />

    CusaBio

    Anti FCGR2A mAb (Clone 3B6)

    Catalog No.(s): CSB-RA163349A0HU, CSB-RA163349A0HU-50, CSB-RA163349A0HU-100

    Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. Product Specifications Application WB,...

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  • IHC image of CSB-RA162924A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti FOLH1 mAb (Clone 6B10)

    Catalog No.(s): CSB-RA162924A0HU, CSB-RA162924A0HU-50, CSB-RA162924A0HU-100

    Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission...

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  • IHC image of CSB-RA162789A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti ICAM1 mAb (Clone 3E9)

    Catalog No.(s): CSB-RA162789A0HU, CSB-RA162789A0HU-50, CSB-RA162789A0HU-100

    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation...

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  • Western Blot<br /> Positive WB detected in: U-251 whole cell lysate, THP-1 whole cell lysate, Ntera-2 whole cell lysate<br /> All lanes: PTH1R antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 67 kDa<br /> Observed band size: 72, 55 kDa<br />

    CusaBio

    Anti PTH1R mAb (Clone 1G7)

    Catalog No.(s): CSB-RA162005A0HU, CSB-RA162005A0HU-50, CSB-RA162005A0HU-100

    Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Product...

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  • Western Blot<br /> Positive WB detected in: K562 whole cell lysate<br /> All lanes: PARP antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 114 kDa<br /> Observed band size: 114 kDa<br />

    CusaBio

    Anti PARP1 mAb (Clone 7C11)

    Catalog No.(s): CSB-RA160472A0HU, CSB-RA160472A0HU-50, CSB-RA160472A0HU-100

    Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an...

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  • IHC image of CSB-RA160202A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti DNMT1 mAb (Clone 1A9)

    Catalog No.(s): CSB-RA160202A0HU, CSB-RA160202A0HU-50, CSB-RA160202A0HU-100

    Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with...

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  • Western Blot<br /> Positive WB detected in: HepG2 whole cell lysate, MCF-7 whole cell lysate, 293 whole cell lysate, HL60 whole cell lysate, Mouse Heart tissue, Mouse Brain tissue<br /> All lanes: ATP5F1A antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 60, 55, 58 kDa<br /> Observed band size: 60 kDa<br />

    CusaBio

    Anti ATP5A1 mAb (Clone 5G11)

    Catalog No.(s): CSB-RA159926A0HU, CSB-RA159926A0HU-50, CSB-RA159926A0HU-100

    Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of...

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  • Western Blot<br /> Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate, HL60 whole cell lysate, THP-1 whole cell lysate, K562 whole cell lysate<br /> All lanes: SUZ12 antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 84 kDa<br /> Observed band size: 90 kDa<br />

    CusaBio

    Anti SUZ12 mAb (Clone 1B10)

    Catalog No.(s): CSB-RA159561A0HU, CSB-RA159561A0HU-50, CSB-RA159561A0HU-100

    Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a...

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  • Western Blot<br /> Positive WB detected in: L02 whole cell lysate, Hela whole cell lysate, PC-3 whole cell lysate, A549 whole cell lysate<br /> All lanes: EGFR antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 135, 45, 78, 70 kDa<br /> Observed band size: 165 kDa<br />

    CusaBio

    Anti EGFR mAb (Clone 9F10)

    Catalog No.(s): CSB-RA159341A0HU, CSB-RA159341A0HU-50, CSB-RA159341A0HU-100

    Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN,...

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  • Western Blot<br /> Positive WB detected in: Jurkat whole cell lysate, K562 whole cell lysate, Hela whole cell lysate, Raji whole cell lysate, HepG2 whole cell lysate<br /> All lanes: FUBP1 antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 68, 69 kDa<br /> Observed band size: 69 kDa<br />

    CusaBio

    Anti FUBP1 mAb (Clone 7C3)

    Catalog No.(s): CSB-RA157765A0HU, CSB-RA157765A0HU-50, CSB-RA157765A0HU-100

    Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription. Product Specifications Application WB, IHC, IF, IP, FC,...

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  • Western Blot<br /> Positive WB detected in: Raji whole cell lysate, K562 whole cell lysate<br /> All lanes: INPP5D antibody at 1:1500<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 134, 110 kDa<br /> Observed band size: 145 kDa<br />

    CusaBio

    Anti INPP5D mAb (Clone 9G11)

    Catalog No.(s): CSB-RA157463A0HU, CSB-RA157463A0HU-50, CSB-RA157463A0HU-100

    Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways...

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  • IHC image of CSB-RA156557A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti SIRT5 mAb (Clone 9H12)

    Catalog No.(s): CSB-RA156557A0HU, CSB-RA156557A0HU-50, CSB-RA156557A0HU-100

    NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693). Activates CPS1 and contributes to the regulation of...

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  • Western Blot<br /> Positive WB detected in: U-251 whole cell lysate, U-87 whole cell lysate<br /> All lanes: PAI1 Antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 46, 44 kDa<br /> Observed band size: 45 kDa<br />

    CusaBio

    Anti SERPINE1 mAb (Clone 10C3)

    Catalog No.(s): CSB-RA156066A0HU, CSB-RA156066A0HU-50, CSB-RA156066A0HU-100

    Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis. Product...

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