CUSABIO

  • Immunofluorescence staining of HepG2 Cells with CSB-RA555849A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

    CusaBio

    Anti FGFR3 mAb (Clone 5B6)

    Catalog No.(s): CSB-RA555849A0HU, CSB-RA555849A0HU-50, CSB-RA555849A0HU-100

    Please click here to view other Bone-related ProductsTyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an...

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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate, 293 whole cell lysate<br />
All lanes: CDK6 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 37 kDa<br />
Observed band size: 37 kDa<br />

    CusaBio

    Anti CDK6 mAb (Clone 8G3)

    Catalog No.(s): CSB-RA555745A0HU, CSB-RA555745A0HU-50, CSB-RA555745A0HU-100

    Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the...

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  • Western Blot<br />
Positive WB detected in: Daudi whole cell lysate, U87 whole cell lysate<br />
All lanes: ACVRL1 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 57 kDa<br />
Observed band size: 65 kDa<br />

    CusaBio

    Anti ACVRL1 mAb (Clone 8B6)

    Catalog No.(s): CSB-RA555022A0HU, CSB-RA555022A0HU-50, CSB-RA555022A0HU-100

    Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type...

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  • Western Blot<br />
Positive WB detected in: HepG2 whole cell lysate, Rat Heart whole cell lysate, Rat Brain whole cell lysate<br />
All lanes: CYP17A1 antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 58 kDa<br />
Observed band size: 58 kDa<br />

    CusaBio

    Anti CYP17A1 mAb (Clone 5A9)

    Catalog No.(s): CSB-RA554990A0HU, CSB-RA554990A0HU-50, CSB-RA554990A0HU-100

    Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual...

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  • Western Blot<br />
Positive WB detected in: K562 whole cell lysate, THP-1 whole cell lysate<br />
All lanes: TACC3 Antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 91 kDa<br />
Observed band size: 140 kDa<br />

    CusaBio

    Anti TACC3 mAb (Clone 10G7)

    Catalog No.(s): CSB-RA553945A0HU, CSB-RA553945A0HU-50, CSB-RA553945A0HU-100

    Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as component of the...

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  • IHC image of CSB-RA553167A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti BTK mAb (Clone 3E5)

    Catalog No.(s): CSB-RA553167A0HU, CSB-RA553167A0HU-50, CSB-RA553167A0HU-100

    Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and...

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  • IHC image of CSB-RA553053A0HU diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti KLKB1 mAb (Clone 9F6)

    Catalog No.(s): CSB-RA553053A0HU, CSB-RA553053A0HU-50, CSB-RA553053A0HU-100

    The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by...

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  • IHC image of CSB-RA552900A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti ENPEP mAb (Clone 2G11)

    Catalog No.(s): CSB-RA552900A0HU, CSB-RA552900A0HU-50, CSB-RA552900A0HU-100

    Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells. Product Specifications Application IHC,...

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  • IHC image of CSB-RA548809A0HU diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti FLNA mAb (Clone 1B2)

    Catalog No.(s): CSB-RA548809A0HU, CSB-RA548809A0HU-50, CSB-RA548809A0HU-100

    Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins...

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  • IHC image of CSB-RA548583A0HU diluted at 1:100 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti KLK3 mAb (Clone 7D4)

    Catalog No.(s): CSB-RA548583A0HU, CSB-RA548583A0HU-50, CSB-RA548583A0HU-100

    Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. Product Specifications Application IHC, ELISA Reactivity Human Clonality Monoclonal (Clone No.: 7D4)

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  • IHC image of CSB-RA548303A0HU diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti ITGAV mAb (Clone 4G7)

    Catalog No.(s): CSB-RA548303A0HU, CSB-RA548303A0HU-50, CSB-RA548303A0HU-100

    The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of...

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  • Overlay histogram showing Hela cells stained with CSB-RA546821A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1µg/1*106cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1µg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.

    CusaBio

    Anti STAT3 mAb (Clone 9C7)

    Catalog No.(s): CSB-RA546821A0HU, CSB-RA546821A0HU-50, CSB-RA546821A0HU-100

    Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed:10688651, PubMed:12359225, PubMed:12873986, PubMed:15194700, PubMed:17344214, PubMed:18242580,...

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  • IHC image of CSB-RA546523A0HU diluted at 1:100 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti RHOA mAb (Clone 3G7)

    Catalog No.(s): CSB-RA546523A0HU, CSB-RA546523A0HU-50, CSB-RA546523A0HU-100

    Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle...

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  • Western Blot<br />
Positive WB detected in: THP-1 whole cell lysate, RAW264.7 whole cell lysate, U-251 whole cell lysate, K562 whole cell lysate<br />
All lanes: TLR5 antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 98 kDa<br />
Observed band size: 98 kDa<br />

    CusaBio

    Anti TLR5 mAb (Clone 10D8)

    Catalog No.(s): CSB-RA545516A0HU, CSB-RA545516A0HU-50, CSB-RA545516A0HU-100

    Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Product...

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  • IHC image of CSB-RA449834A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti CLU mAb (Clone 2A1)

    Catalog No.(s): CSB-RA449834A0HU, CSB-RA449834A0HU-50, CSB-RA449834A0HU-100

    Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and...

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  • Western Blot<br />
Positive WB detected in: U251 whole cell lysate, MCF-7 whole cell lysate, U87 whole cell lysate<br />
All lanes: TNFRSF12A antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 14, 11 kD<br />
Observed band size: 14 kDa<br />

    CusaBio

    Anti TNFRSF12A mAb (Clone 7H8)

    Catalog No.(s): CSB-RA441307A0HU, CSB-RA441307A0HU-50, CSB-RA441307A0HU-100

    Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. Product Specifications Application WB, IHC,...

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  • Western Blot<br />
Positive WB detected in: A549 whole cell lysate, 293T whole cell lysate, K562 whole cell lysate<br />
All lanes: CD55 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 42, 49, 40, 57, 60 kDa<br />
Observed band size: 70 kDa<br />

    CusaBio

    Anti CD55 mAb (Clone 1A5)

    Catalog No.(s): CSB-RA440943A0HU, CSB-RA440943A0HU-50, CSB-RA440943A0HU-100

    This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes...

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  • Western Blot<br />
Positive WB detected in: MCF-7 whole cell lysate<br />
All lanes: EPCAM antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 35 kDa<br />
Observed band size: 35 kDa<br />

    CusaBio

    Anti EPCAM mAb (Clone 6H12)

    Catalog No.(s): CSB-RA439934A0HU, CSB-RA439934A0HU-50, CSB-RA439934A0HU-100

    May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection...

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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, Jurkat whole cell lysate, 293T whole cell lysate, MCF-7 whole cell lysate, HL60 whole cell lysate<br />
All lanes: HMGB1 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 25 kDa<br />
Observed band size: 25 kDa<br />

    CusaBio

    Anti HMGB1 mAb (Clone 1A1)

    Catalog No.(s): CSB-RA439052A0HU, CSB-RA439052A0HU-50, CSB-RA439052A0HU-100

    Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin...

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  • IHC image of CSB-RA437590A0HU diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti TTR mAb (Clone 3F6)

    Catalog No.(s): CSB-RA437590A0HU, CSB-RA437590A0HU-50, CSB-RA437590A0HU-100

    Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Product Specifications Application IHC, ELISA Reactivity Human Clonality Monoclonal (Clone No.: 3F6)

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  • Western Blot<br />
Positive WB detected in Hela whole cell lysate,A549 whole cell lysate(treated with Calyculin A or EGF)<br />
All lanes Phospho-CDK1/CDK2/CDK3 antibody at 0.76μg/ml<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 34 KDa<br />
Observed band size: 34 KDa<br />

    CusaBio

    Anti Phospho-CDK1/CDK2/CDK3 (T14) mAb (Clone 4C12)

    Catalog No.(s): CSB-RA361848A14phHU, CSB-RA361848A14phHU-50, CSB-RA361848A14phHU-100

    Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required...

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  • The Binding Activity of SARS-CoV-2-N Antibody with SARS-CoV-2-N<br />Activity: Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-N at 2 μg/ml can bind SARS-CoV-2-N Antibody, the EC<sub>50</sub> is 2.928 ng/ml.

    CusaBio

    Anti N mAb (Clone 4D2)

    Catalog No.(s): CSB-RA33255A2GMY, CSB-RA33255A2GMY-50, CSB-RA33255A2GMY-100

    Product Specifications Application ELISA, GICA Reactivity Human, SARS Caronavirus Clonality Monoclonal (Clone No.: 4D2)

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  • <strong>Activity Assay- ELISA</strong><br />The Binding Activity of SARS-CoV-2 Spike RBD Nanobody with SARS-CoV-2-S1-RBD<br />Activity: Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-S1-RBD (<a href='https://www.cusabio.com/Recombinant-Protein/Recombinant-Human-Novel-Coronavirus-Spike-glycoprotein-S---partial-12928552.html'>CSB-YP3324GMY1</a>) at 2 &mu;g/ml can bind SARS-CoV-2 Spike RBD Nanobody, the EC<sub>50</sub>&nbsp;is 0.8674 ng/ml.

    CusaBio

    Anti SARS-CoV-2 Spike RBD Nanobody mAb (Clone A1)

    Catalog No.(s): CSB-RA33245A2GMY, CSB-RA33245A2GMY-50, CSB-RA33245A2GMY-100

    Recombinant anti-SARS-CoV-2 spike VHH is expressed from 293 cells (HEK293) with a human IgG1 Fc tag on C-terminal. Product Specifications Application ELISA, GICA Reactivity Human, SARS Caronavirus Clonality Monoclonal (Clone No.:...

    $420.00 - $700.00
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  • Western Blot<br />
Positive WB detected in: THP-1 whole cell lysate, K562 whole cell lysate<br />
All lanes: C3 antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 188 kDa<br />
Observed band size: 115 kDa<br />

    CusaBio

    Anti C3 mAb (Clone 4D12)

    Catalog No.(s): CSB-RA303909A0HU, CSB-RA303909A0HU-50, CSB-RA303909A0HU-100

    C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to...

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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, Jurkat whole cell lysate, HL60 whole cell lysate<br />
All lanes: HDAC1 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 56 kDa<br />
Observed band size: 60 kDa<br />

    CusaBio

    Anti HDAC1 mAb (Clone 10A1)

    Catalog No.(s): CSB-RA299884A0HU, CSB-RA299884A0HU-50, CSB-RA299884A0HU-100

    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle...

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  • Immunofluorescence staining of Hela Cells with CSB-RA299200A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

    CusaBio

    Anti RPS6KB1 mAb (Clone 7D4)

    Catalog No.(s): CSB-RA299200A0HU, CSB-RA299200A0HU-50, CSB-RA299200A0HU-100

    Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6...

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  • IHC image of CSB-RA297464A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti CCR2 mAb (Clone 6A1)

    Catalog No.(s): CSB-RA297464A0HU, CSB-RA297464A0HU-50, CSB-RA297464A0HU-100

    Receptor for the CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing intracellular calcium ion levels. Alternative coreceptor with CD4 for HIV-1 infection. Product Specifications Application IHC,...

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  • IHC image of CSB-RA297401A0HU diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti SLC2A1 mAb (Clone 2E1)

    Catalog No.(s): CSB-RA297401A0HU, CSB-RA297401A0HU-50, CSB-RA297401A0HU-100

    Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Product...

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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate, Rat liver tissue, Rat kidney tissue<br />
All lanes: AIFM1 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 67, 36, 29, 27 kDa<br />
Observed band size: 67 kDa<br />

    CusaBio

    Anti AIFM1 mAb (Clone 4B2)

    Catalog No.(s): CSB-RA296617A0HU, CSB-RA296617A0HU-50, CSB-RA296617A0HU-100

    Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a...

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  • IHC image of CSB-RA294332A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti METAP2 mAb (Clone 8F2)

    Catalog No.(s): CSB-RA294332A0HU, CSB-RA294332A0HU-50, CSB-RA294332A0HU-100

    Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic...

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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate<br />
All lanes: SA2 antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 142, 146 kDa<br />
Observed band size: 142 kDa<br />

    CusaBio

    Anti STAG2 mAb (Clone 3H4)

    Catalog No.(s): CSB-RA292183A0HU, CSB-RA292183A0HU-50, CSB-RA292183A0HU-100

    Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is...

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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, HL60 whole cell lysate, 293T whole cell lysate, K562 whole cell lysate<br />
All lanes: CASP2 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 51, 35, 11 kDa<br />
Observed band size: 51 kDa<br />

    CusaBio

    Anti CASP2 mAb (Clone 7E5)

    Catalog No.(s): CSB-RA291376A0HU, CSB-RA291376A0HU-50, CSB-RA291376A0HU-100

    Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Product...

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