CUSABIO

  • IHC image of CSB-RA850851A358phHU diluted at 1:100 and staining in paraffin-embedded human melanoma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

    CusaBio

    Anti Phospho-MLKL (S358) mAb (Clone 4A6)

    Catalog No.(s): CSB-RA850851A358phHU, CSB-RA850851A358phHU-50, CSB-RA850851A358phHU-100

    Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis...

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  • IHC image of CSB-RA847116A0HU diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti HSPA5 mAb (Clone 4H12)

    Catalog No.(s): CSB-RA847116A0HU, CSB-RA847116A0HU-50, CSB-RA847116A0HU-100

    Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to...

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  • Western Blot<br />
Positive WB detected in: K562 whole cell lysate<br />
All lanes: DGCR8 antibody at 2.65μg/ml<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 87, 33, 83 KDa<br />
Observed band size: 100 KDa<br />

    CusaBio

    Anti DGCR8 mAb (Clone 2H2)

    Catalog No.(s): CSB-RA845175A0HU, CSB-RA845175A0HU-50, CSB-RA845175A0HU-100

    Component of the microprocessor complex that acts as a RNA- and heme-binding protein that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts...

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  • Western Blot<br />
Positive WB detected in: 293 whole cell lysate, HepG2 whole cell lysate, Jurkat whole cell lysate, THP-1 whole cell lysate<br />
All lanes: TMEM173 antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 43 kDa<br />
Observed band size: 43 kDa<br />

    CusaBio

    Anti TMEM173 mAb (Clone 7C7)

    Catalog No.(s): CSB-RA843206A0HU, CSB-RA843206A0HU-50, CSB-RA843206A0HU-100

    Facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded...

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    Anti SEMA4D Monoclonal mAb (Clone 21E8)

    Catalog No.(s): CSB-RA835707A1HU, CSB-RA835707A1HU-50, CSB-RA835707A1HU-100

    Product Specifications Application FC, ELISA Reactivity Human Clonality Monoclonal (Clone No.: 2100000000)

    $210.00 - $350.00
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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, 293T whole cell lysate, PC3 whole cell lysate, U87 whole cell lysate, Mouse kidney tissue<br />
All lanes: NDRG1 antibody at 0.7μg/ml<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 43, 36, 34 KDa<br />
Observed band size: 43 KDa<br />

    CusaBio

    Anti NDRG1 mAb (Clone 4C8)

    Catalog No.(s): CSB-RA835678A0HU, CSB-RA835678A0HU-50, CSB-RA835678A0HU-100

    Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking,...

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  • Western Blot<br />
Positive WB detected in: Ntera-2 whole cell lysate<br />
All lanes: pro Caspase 3 antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 32 kDa<br />
Observed band size: 32 kDa<br />

    CusaBio

    Anti CASP3 mAb (Clone 6B2)

    Catalog No.(s): CSB-RA833808A0HU, CSB-RA833808A0HU-50, CSB-RA833808A0HU-100

    Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element...

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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, L02 whole cell lysate, HepG2 whole cell lysate<br />
All lanes: MGEA5 antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 103, 96, 77, 97 kDa<br />
Observed band size: 130 kDa<br />

    CusaBio

    Anti MGEA5 mAb (Clone 8D12)

    Catalog No.(s): CSB-RA833565A0HU, CSB-RA833565A0HU-50, CSB-RA833565A0HU-100

    Isoform 1: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:11148210). Does not...

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  • Western Blot<br />
Positive WB detected in: 293 whole cell lysate, Hela whole cell lysate, Jurkat whole cell lysate, MCF-7 whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate<br />
All lanes: SOD1 antibody at 1:1500<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 16 kDa<br />
Observed band size: 18 kDa<br />

    CusaBio

    Anti SOD1 mAb (Clone 3E5)

    Catalog No.(s): CSB-RA829583A0HU, CSB-RA829583A0HU-50, CSB-RA829583A0HU-100

    Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Product Specifications Application WB, FC, ELISA Reactivity Human Clonality Monoclonal (Clone No.: 300000)

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  • IHC image of CSB-RA827375A0HU diluted at 1:100 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti SSTR2 mAb (Clone 1C3)

    Catalog No.(s): CSB-RA827375A0HU, CSB-RA827375A0HU-50, CSB-RA827375A0HU-100

    Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive...

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  • IHC image of CSB-RA827145A0HU diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti SNAP23 mAb (Clone 2D8)

    Catalog No.(s): CSB-RA827145A0HU, CSB-RA827145A0HU-50, CSB-RA827145A0HU-100

    Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. Product Specifications Application IHC, ELISA Reactivity Human Clonality Monoclonal...

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  • Western Blot<br />
Positive WB detected in: Jurkat whole cell lysate, PC-3 whole cell lysate, Rat Heart tissue<br />
All lanes: E2F1 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 47 kDa<br />
Observed band size: 60 kDa<br />

    CusaBio

    Anti E2F1 mAb (Clone 1D12)

    Catalog No.(s): CSB-RA826096A0HU, CSB-RA826096A0HU-50, CSB-RA826096A0HU-100

    Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The...

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  • Western Blot<br />
Positive WB detected in: U-251 whole cell lysate<br />
All lanes: Mutant p53 antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 38, 39, 40, 34, 35, 30, 24, 25 kDa<br />
Observed band size: 53 kDa<br />

    CusaBio

    Anti TP53 mAb (Clone 5C3)

    Catalog No.(s): CSB-RA825742A0HU, CSB-RA825742A0HU-50, CSB-RA825742A0HU-100

    Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by...

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  • Immunofluorescence staining of Hela Cells with CSB-RA825204A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

    CusaBio

    Anti AKR1C3 mAb (Clone 4D12)

    Catalog No.(s): CSB-RA825204A0HU, CSB-RA825204A0HU-50, CSB-RA825204A0HU-100

    Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and...

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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, K562 whole cell lysate, Jurkat whole cell lysate, HL60 whole cell lysate<br />
All lanes: TBP antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 38, 36 kDa<br />
Observed band size: 36 kDa<br />

    CusaBio

    Anti TBP mAb (Clone 3C7)

    Catalog No.(s): CSB-RA821481A0HU, CSB-RA821481A0HU-50, CSB-RA821481A0HU-100

    General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682). Binding of TFIID to the TATA box is the initial transcriptional step...

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  • CusaBio

    Anti RIOX2 mAb (Clone 1E8)

    Catalog No.(s): CSB-RA810267A0HU, CSB-RA810267A0HU-50, CSB-RA810267A0HU-100

    Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the...

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  • Western Blot<br />
Positive WB detected in 293 whole cell lysate锛孉549 whole cell lysate<br />
All lanes Phospho-PRKAA2 antibody at 1.1μg/ml<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 62 KDa<br />
Observed band size: 62 KDa<br />

    CusaBio

    Anti Phospho-PRKAA2 (S491) mAb (Clone 3H10)

    Catalog No.(s): CSB-RA805325A491phHU, CSB-RA805325A491phHU-50, CSB-RA805325A491phHU-100

    Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and...

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  • Western Blot<br />
Positive WB detected in 293 whole cell lysate锛孉549 whole cell lysate(treated with Calyculin A or EGF)<br />
All lanes Phospho-PRKAA2 antibody at 1.95μg/ml<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 62 KDa<br />
Observed band size: 62 KDa<br />

    CusaBio

    Anti Phospho-PRKAA2 (Thr172) mAb (Clone 4F4)

    Catalog No.(s): CSB-RA805325A172phHU, CSB-RA805325A172phHU-50, CSB-RA805325A172phHU-100

    Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and...

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  • IHC image of CSB-RA802195A0HU diluted at 1:100 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti HTT mAb (Clone 6F2)

    Catalog No.(s): CSB-RA802195A0HU, CSB-RA802195A0HU-50, CSB-RA802195A0HU-100

    May play a role in microtubule-mediated transport or vesicle function. Product Specifications Application IHC, ELISA Reactivity Human Clonality Monoclonal (Clone No.: 6F2)

    $210.00 - $350.00
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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate, HepG2 whole cell lysate<br />
All lanes: CD47 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 36, 32, 34 kDa<br />
Observed band size: 55 kDa<br />

    CusaBio

    Anti CD47 mAb (Clone 4G11)

    Catalog No.(s): CSB-RA802124A0HU, CSB-RA802124A0HU-50, CSB-RA802124A0HU-100

    Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA,...

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  • IHC image of CSB-RA801238A0HU diluted at 1:100 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

    CusaBio

    Anti CD163 mAb (Clone 7B2)

    Catalog No.(s): CSB-RA801238A0HU, CSB-RA801238A0HU-50, CSB-RA801238A0HU-100

    Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron,...

    $210.00 - $350.00
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  • Western Blot<br />
Positive WB detected in: Ntera-2 whole cell lysate, Mouse Liver whole cell lysate, Rat Liver cell lysate<br />
All lanes: ALDH2 antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 57, 51 kDa<br />
Observed band size: 57 kDa<br />

    CusaBio

    Anti ALDH2 mAb (Clone 3F10)

    Catalog No.(s): CSB-RA799763A0HU, CSB-RA799763A0HU-50, CSB-RA799763A0HU-100

    extracellular exosome, mitochondrial matrix, aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase [NAD(P)+] activity, electron carrier activity, NAD binding, alcohol metabolic process, carbohydrate metabolic process, ethanol oxidation Product...

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  • IHC image of CSB-RA799368A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti MFN2 mAb (Clone 10F6)

    Catalog No.(s): CSB-RA799368A0HU, CSB-RA799368A0HU-50, CSB-RA799368A0HU-100

    Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:11181170, PubMed:11950885, PubMed:28114303). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between...

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  • IHC image of CSB-RA798840A0HU diluted at 1:100 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti TERT mAb (Clone 5C11)

    Catalog No.(s): CSB-RA798840A0HU, CSB-RA798840A0HU-50, CSB-RA798840A0HU-100

    Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase...

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  • Immunofluorescence staining of Hela Cells with CSB-RA797631A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

    CusaBio

    Anti ADAM17 mAb (Clone 5A1)

    Catalog No.(s): CSB-RA797631A0HU, CSB-RA797631A0HU-50, CSB-RA797631A0HU-100

    Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins,...

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  • IHC image of CSB-RA797150A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti LRRK2 mAb (Clone 4E9)

    Catalog No.(s): CSB-RA797150A0HU, CSB-RA797150A0HU-50, CSB-RA797150A0HU-100

    Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release...

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  • Western Blot<br />
Positive WB detected in: THP-1 whole cell lysate<br />
All lanes: CD38 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 35, 14 kDa<br />
Observed band size: 42 kDa<br />

    CusaBio

    Anti CD38 mAb (Clone 6F10)

    Catalog No.(s): CSB-RA796695A0HU, CSB-RA796695A0HU-50, CSB-RA796695A0HU-100

    Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune...

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  • IHC image of CSB-RA796310A0HU diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti ATP1A1 mAb (Clone 4C3)

    Catalog No.(s): CSB-RA796310A0HU, CSB-RA796310A0HU-50, CSB-RA796310A0HU-100

    This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions,...

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  • IHC image of CSB-RA794900A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti GZMB mAb (Clone 6A1)

    Catalog No.(s): CSB-RA794900A0HU, CSB-RA794900A0HU-50, CSB-RA794900A0HU-100

    This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves...

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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, L02 whole cell lysate, HepG2 whole cell lysate<br />
All lanes: EGFR antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 135, 45, 78, 70 kDa<br />
Observed band size: 150 kDa<br />

    CusaBio

    Anti EGFR mAb (Clone 5D4)

    Catalog No.(s): CSB-RA794061A0HU, CSB-RA794061A0HU-50, CSB-RA794061A0HU-100

    Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN,...

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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, K562 whole cell lysate, HL60 whole cell lysate, PC-3 whole cell lysate<br />
All lanes: TOP1 antibody at 1:2000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 91 kDa<br />
Observed band size: 91 kDa<br />

    CusaBio

    Anti TOP1 mAb (Clone 6D8)

    Catalog No.(s): CSB-RA792129A0HU, CSB-RA792129A0HU-50, CSB-RA792129A0HU-100

    Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site...

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  • IHC image of CSB-RA788455A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti CTSS mAb (Clone 9B10)

    Catalog No.(s): CSB-RA788455A0HU, CSB-RA788455A0HU-50, CSB-RA788455A0HU-100

    Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. Product...

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  • IHC image of CSB-RA787345A0HU diluted at 1:100 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

    CusaBio

    Anti FBP1 mAb (Clone 4G3)

    Catalog No.(s): CSB-RA787345A0HU, CSB-RA787345A0HU-50, CSB-RA787345A0HU-100

    Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic...

    $210.00 - $350.00
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  • Western Blot<br />
Positive WB detected in: HepG2 whole cell lysate, Hela whole cell lysate, 293T whole cell lysate, Jurkat whole cell lysate, Raji whole cell lysate, K562 whole cell lysate<br />
All lanes: TRAF2 antibody at 1:1500<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 56, 62, 55, 54 kDa<br />
Observed band size: 56 kDa<br />

    CusaBio

    Anti TRAF2 mAb (Clone 9A5)

    Catalog No.(s): CSB-RA786226A0HU, CSB-RA786226A0HU-50, CSB-RA786226A0HU-100

    Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked...

    $210.00 - $350.00
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  • Western Blot<br />
Positive WB detected in: Hela whole cell lysate<br />
All lanes: Xanthine Oxidase antibody at 1:1000<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 147 kDa<br />
Observed band size: 147 kDa<br />

    CusaBio

    Anti XDH mAb (Clone 8A9)

    Catalog No.(s): CSB-RA785778A0HU, CSB-RA785778A0HU-50, CSB-RA785778A0HU-100

    Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro)...

    $210.00 - $350.00
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