MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases. Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.
Product Specifications | |
Application | FC |
Reactivity | Mouse |
Conjugation | PE |
Peptide Sequence | AVEIHRPVPGTAPPS |
Citations for T-Select I-Ab T. gondii CD4Ag28m605-619 Tetramer-PE – 1 Found |
Liao, Ting-Yu Angela; Lau, Alice; Joseph, Sunil; Hytönen, Vesa; Hmama, Zakaria. Improving the Immunogenicity of the Mycobacterium bovis BCG Vaccine by Non-Genetic Bacterial Surface Decoration Using the Avidin-Biotin System. Plos One. 10(12):e0145833. PubMed |