Cosmo Bio USA, in collaboration with MBL International, provides a comprehensive custom MHC monomer and tetramer service designed to support advanced immunological research. Researchers can request tetramers tailored to specific MHC alleles and peptide sequences, enabling precise detection and monitoring of antigen-specific T cells. This service encompasses a broad selection of over 60 MHC alleles across various species, including human, mouse, rhesus macaque, and chicken . Notably, MBL's tetramers incorporate a patented mutation in the MHC class I heavy chain (alanine to valine at position 245), which minimizes non-specific CD8-MHC interactions, thereby enhancing specificity and reducing background staining.

PUREfrex custom kits are your convenient route to applications and experiments limited only by your imagination. Tell us what you need. If technically feasible, Gene Frontier will do all they can to meet your specifications and timelines.

Cosmo Bio USA partners with CUSABIO to provide custom protein expression services tailored to the specific needs of life science researchers. This collaboration offers access to a variety of expression systems, including bacterial, mammalian, and insect cells, ensuring optimal protein yield and functionality. Starting from gene synthesis or client-provided cDNA, the process encompasses subcloning, expression optimization, purification, and quality control analyses such as SDS-PAGE. This comprehensive service enables researchers to obtain high-quality recombinant proteins for a wide range of experimental applications.