Rhodocytin (also called as aggretin), a snake venom protein obtained from the Malayan pit viper Calloselasma rhodostoma, induces platelet aggregation through C-type lectin-like receptor 2 (CLEC-2). It is classified as snacles (Snake venom C-type lectins), having a basic heterodimeric structure with two subunits, α (136 amino acids) and β (123 amino acids), that are nearly always linked covalently via a disulfide bond. Recently, it has been reported that rhodocytin forms larger complex such as heterooctamer. This product is a recombinant protein that is functionally equivalent to natural rhodocytin.
