Native collagen, Bovine dermis, 3mg/mL

Cosmo Bio

SKU:
KOU-IAC-30
  • Three-dimensional culture of blood vessel endothelium using the collagen gel (Eguchi R, Hyogo College of Medicine Department of Environmental and Preventive Medicine)

An immunosuppressant FK506 is known to be involved in endothelial dysfunction inducing thrombotic microangiopathy after hematopoietic stem cell transplantation. In order to clarify the mechanism of the event, human umbilical vein endothelial cells (HUVEC) in collagen gel 3D culture were treated with FK506. In 3D culture, FK506 induced cell death and tube structure breakdown in a time- and concentration-dependent manner, but showed little effect on cells in monolayer culture. These results suggest 3D culture in collagen gel is useful to investigate in vivo phenomenon in vitro (Ref.6).
  • Comparison of albumin production of rat primary hepatocyte by various culture methods

1 uncoated
2 atelocollagen gel
3 native collagen gel
4 atelocollagen coated plate 5 native collagen coated plate 6 Company A’s coated plate 7 Company B’s coated plate 8 gelatin coated plate

Higher albumin production was maintained when cells were cultured on Atelocollagen and Native collagen gels ( 2 , 3 ) compared to other culture methods tested. In addition, results with both pre-coated plates ( 6 , 7 ) were similar to gelatin coated plates ( 8 ), suggesting that collagen degrades during storage.
  • Cell polarity formation of renal epithelial cells using collagen gel (Yonemura S, RIKEN Center for Life Science Technologies Ultrastructural Research Team)

Localization of ZO-1 (tight junction) and PKC Zeta (apical membrane) markers were observed inside spheroids of Madin-Darby canine kidney (MDCK) II cells cultured in collagen gel. On the other hand, localization of Scrib, a basal marker, was observed at the outer surface of spheroids. Thus, collagen gel 3D culture is effective for the formation of apical-basal polarity. Furthermore, collagen gel cultures showed a higher rate of single lumen formation compared to Matrigel and hanging drop culture (Ref. 4).
  • Invasion assay of cervical cancer cells in collagen gel (Uekita T, et al. National Defense Academy Division of Genome Biology)

Human cervical cancer cells (HCK1T-E cells) and active Ras transfected HCK1T-E cells (HCK1T-E-Hras cells) were seeded on collagen gel containing human fibroblast cells (Raft) to evaluate association between CDCP1 expression and cancer cell invasion. As a result, invasion of HCK1t-E-Hras cells into Raft was observed and remarkable expression of CDCP1 was detected in the invasion site. In addition, invasion into Raft was inhibited by CDCP1 siRNA transfection. Therefore, it was shown that the collagen gel was useful as a cancer cell invasion model to the submucosa (Ref. 3).
  • How to use Collagen Solutions
  • Molecular Structure of Atelocollagen and Native Collagen
  • Comparison list of the collagen solution products
  • Native collagen, Bovine dermis, 3mg/mL
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Background
Highly purified collagen solution (pH 3.0) for cell culture. Suitable for cell cultureware coating and preparing collagen gels. The low pH of the Acid Solutions enables long term refrigerated storage. In contrast to cell-derived soluble basement membrane preparations, Collagen Solutions are free from bioactive substances, nucreic acids, MMP, etc. allowing experimental results to be evaluated more clearly.

Applications

  • Collagen coating for cell cultureware
  • Cell culture in a collagen gel
  • Cell culture on a collagen gel

Features

  • Native collagen gelates when neutralized and placed under physiological condition.
  • Ready-to-use: atelocollagen is premixed with medium

This product is manufactured in Japan and produced from raw materials obtained from livestock certified born and raised in Australia or New Zealand. Japan, Australia and New Zealand are all recognized by the World Health Organization as having negligible risk for Bovine Spongiform Encephalitis (BSE). Nevertheless, please consult with your country's Customs office to confirm importability.






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Citations for Native collagen, Bovine dermis, 3mg/mL – 272 Found
Lee, Michelle H; Goralczyk, Anna G; Kriszt, Rókus; Ang, Xiu Min; Badowski, Cedric; Li, Ying; Summers, Scott A; Toh, Sue-Anne; Yassin, M Shabeer; Shabbir, Asim; Sheppard, Allan; Raghunath, Michael. ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs. Scientific Reports. 2016;6( 26883894):21173.  PubMed
Leggett, Susan E; Brennan, Molly C; Martinez, Sophia; Tien, Joe; Nelson, Celeste M. Relatively Rare Populations of Invasive Cells Drive Progression of Heterogeneous Tumors. Cellular And Molecular Bioengineering. 2024;17(1):7-24.  PubMed
Comments: IAC 3D culture
Murakami, Shizuko; Ohki-Hamazaki, Hiroko; Uchiyama, Yasuo. Somatostatin affects GnRH neuronal development and migration and stimulates olfactory-related fiber fasciculation. Developmental Neurobiology. 2024;84(1):3-17.  PubMed
Comments: IAC 3D culture
Tanimizu, Naoki; Ichinohe, Norihisa; Mitaka, Toshihiro. β-adrenergic receptor agonist promotes ductular expansion during 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced chronic liver injury. Scientific Reports. 2023;13(1):7084.  PubMed
Comments: IAC 3D culture
Tosa, Mamiko; Abe, Yoshinori; Egawa, Seiko; Hatakeyama, Tomoka; Iwaguro, Chihiro; Mitsugi, Ryotaro; Moriyama, Ayaka; Sano, Takumi; Ogawa, Rei; Tanaka, Nobuyuki. The HEDGEHOG-GLI1 pathway is important for fibroproliferative properties in keloids and as a candidate therapeutic target. Communications Biology. 2023;6(1):1235.  PubMed
Comments: IAC 3D culture
Ichise, Shinichiro F; Koide, Takaki. Synthetic Collagen-like Polymer That Undergoes a Sol-Gel Transition Triggered by O-N Acyl Migration at Physiological pH. International Journal Of Molecular Sciences. 2022;23(3)  PubMed
Comments: IAC 3D culture
Imai, Yukiko; Mori, Nobuhito; Nihashi, Yuma; Kumagai, Yutaro; Shibuya, Yoichiro; Oshima, Junya; Sasaki, Masahiro; Sasaki, Kaoru; Aihara, Yukiko; Sekido, Mitsuru; Kida, Yasuyuki S. Therapeutic Potential of Adipose Stem Cell-Derived Conditioned Medium on Scar Contraction Model. Biomedicines. 2022;10(10)  PubMed
Comments: IAC 3D culture
Shinagawa, Takuya; Miyata, Shogo. Three-Dimensional Cell Drawing Technique in Hydrogel Using Micro Injection System. Micromachines. 2022;13(11)  PubMed
Comments: IAC 3D culture
Sugahara, Yurika; Komorisono, Masahiko; Kuwajima, Mami; Yoshikawa, Shuichi; Yoshida, Shiori; Maeda, Kazuhisa. Anti-skin-aging effects of human ceramides via collagen and fibrillin expression in dermal fibroblasts. Bioscience, Biotechnology, And Biochemistry. 2022;86(9):1240-1246.  PubMed
Comments: IAC 3D culture
Aoki, Kana; Harada, Shota; Kawaji, Keita; Matsuzawa, Kenji; Uchida, Seiichi; Ikenouchi, Junichi. STIM-Orai1 signaling regulates fluidity of cytoplasm during membrane blebbing. Nature Communications. 2021;12(1):480.  PubMed
Comments: IAC 3D culture
Imashiro, Chikahiro; Azuma, Tetsuya; Itai, Shun; Kuribara, Taiki; Totani, Kiichiro; Onoe, Hiroaki; Takemura, Kenjiro. Travelling ultrasound promotes vasculogenesis of three-dimensional-monocultured human umbilical vein endothelial cells. Biotechnology And Bioengineering. 2021;118(10):3760-3769.  PubMed
Comments: IAC 3D culture
Rabie, Emann M; Zhang, Sherry X; Kourouklis, Andreas P; Kilinc, A Nihan; Simi, Allison K; Radisky, Derek C; Tien, Joe; Nelson, Celeste M. Matrix degradation and cell proliferation are coupled to promote invasion and escape from an engineered human breast microtumor. Integrative Biology : Quantitative Biosciences From Nano To Macro. 2021;13(1):17-29.  PubMed
Comments: IAC 3D culture
Kawasoe, Ryotaro; Shinoda, Tomoyasu; Hattori, Yuki; Nakagawa, Mami; Pham, Trung Quang; Tanaka, Yoshihiro; Sagou, Ken; Saito, Kanako; Katsuki, Satoru; Kotani, Tomomi; Sano, Akihito; Fujimori, Toshihiko; Miyata, Takaki. Two-photon microscopic observation of cell-production dynamics in the developing mammalian neocortex in utero. Development, Growth & Differentiation. 2020;62(2):118-128.  PubMed
Comments: IAC 3D culture
Kojima, Chie; Nishio, Misaki; Nakajima, Yusuke; Kawano, Takeshi; Takatsuka, Kenji; Matsumoto, Akikazu. Rapid Photoinduced Single Cell Detachment from Gold Nanoparticle-Embedded Collagen Gels with Low Denaturation Temperature. Polymers. 2020;12(1)  PubMed
Comments: IAC 3D culture
Tien, Joe; Dance, Yoseph W; Ghani, Usman; Seibel, Alex J; Nelson, Celeste M. Interstitial Hypertension Suppresses Escape of Human Breast Tumor Cells Via Convection of Interstitial Fluid. Cellular And Molecular Bioengineering. 2021;14(2):147-159.  PubMed
Comments: IAC 3D culture
Yoshino, Daisuke; Funamoto, Kenichi; Sato, Kakeru; Kenry; Sato, Masaaki; Lim, Chwee Teck. Hydrostatic pressure promotes endothelial tube formation through aquaporin 1 and Ras-ERK signaling. Communications Biology. 2020;3(1):152.  PubMed
Comments: IAC 3D culture
Kinoshita-Kawada, Mariko; Hasegawa, Hiroshi; Hongu, Tsunaki; Yanagi, Shigeru; Kanaho, Yasunori; Masai, Ichiro; Mishima, Takayasu; Chen, Xiaoping; Tsuboi, Yoshio; Rao, Yi; Yuasa-Kawada, Junichi; Wu, Jane Y. A crucial role for Arf6 in the response of commissural axons to Slit. Development (Cambridge, England). 2019;146(3)  PubMed
Comments: IAC 3D culture
Kinoshita, Sho; Mera, Katsumi; Ichikawa, Hiroko; Shimasaki, Satoko; Nagai, Mime; Taga, Yuki; Iijima, Katsumasa; Hattori, Shunji; Fujiwara, Yukio; Shirakawa, Jun-Ichi; Nagai, Ryoji. N(ω) -(Carboxymethyl)arginine Is One of the Dominant Advanced Glycation End Products in Glycated Collagens and Mouse Tissues. Oxidative Medicine And Cellular Longevity. 2019( 31583049):9073451.  PubMed
Comments: IAC 3D culture
Morikura, Takashi; Miyata, Shogo. Effect of Mechanical Compression on Invasion Process of Malignant Melanoma Using In Vitro Three-Dimensional Cell Culture Device. Micromachines. 2019;10(10)  PubMed
Comments: IAC 3D culture
Noda, Sonoko; Kawashima, Nobuyuki; Yamamoto, Mioko; Hashimoto, Kentaro; Nara, Keisuke; Sekiya, Ichiro; Okiji, Takashi. Effect of cell culture density on dental pulp-derived mesenchymal stem cells with reference to osteogenic differentiation. Scientific Reports. 2019;9(1):5430.  PubMed
Comments: IAC 3D culture
Nagai, Nao; Ohguchi, Hiroto; Nakaki, Ryo; Matsumura, Yoshihiro; Kanki, Yasuharu; Sakai, Juro; Aburatani, Hiroyuki; Minami, Takashi. Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition. Plos Genetics. 2018;14(11):e1007826.  PubMed
Comments: IAC 3D culture
Shinoda, Tomoyasu; Nagasaka, Arata; Inoue, Yasuhiro; Higuchi, Ryo; Minami, Yoshiaki; Kato, Kagayaki; Suzuki, Makoto; Kondo, Takefumi; Kawaue, Takumi; Saito, Kanako; Ueno, Naoto; Fukazawa, Yugo; Nagayama, Masaharu; Miura, Takashi; Adachi, Taiji; Miyata, Takaki. Elasticity-based boosting of neuroepithelial nucleokinesis via indirect energy transfer from mother to daughter. Plos Biology. 2018;16(4):e2004426.  PubMed
Comments: IAC 3D culture
Watanabe, Yuto; Kawaue, Takumi; Miyata, Takaki. Differentiating cells mechanically limit the interkinetic nuclear migration of progenitor cells to secure apical cytogenesis. Development (Cambridge, England). 2018;145(14)  PubMed
Comments: IAC 3D culture
Ahn, Mok-Ryeon; Bae, Ji-Yeon; Jeong, Da-Hye; Takahashi, Hideaki; Uto, Yoshihiro; Maruta, Hiroshi. Both triazolyl ester of ketorolac (15K) and YM155 inhibit the embryonic angiogenesis in ovo (fertilized eggs) via their common PAK1-survivin/VEGF signaling pathway. Drug Discoveries & Therapeutics. 11(6):300-306.  PubMed
Comments: IAC 3D culture
Giménez, Alícia; Duch, Paula; Puig, Marta; Gabasa, Marta; Xaubet, Antoni; Alcaraz, Jordi. Dysregulated Collagen Homeostasis by Matrix Stiffening and TGF-β1 in Fibroblasts from Idiopathic Pulmonary Fibrosis Patients: Role of FAK/Akt. International Journal Of Molecular Sciences. 2017;18(11)  PubMed
Comments: IAC 3D culture
Piotrowski-Daspit, Alexandra S; Nerger, Bryan A; Wolf, Abraham E; Sundaresan, Sankaran; Nelson, Celeste M. Dynamics of Tissue-Induced Alignment of Fibrous Extracellular Matrix. Biophysical Journal. 2017;113(3):702-713.  PubMed
Comments: IAC 3D culture
Caiazzo, Massimiliano; Okawa, Yuya; Ranga, Adrian; Piersigilli, Alessandra; Tabata, Yoji; Lutolf, Matthias P. Defined three-dimensional microenvironments boost induction of pluripotency. Nature Materials. 2016;15(3):344-52.  PubMed
Comments: IAC 3D culture
Lee, Michelle H; Goralczyk, Anna G; Kriszt, Rókus; Ang, Xiu Min; Badowski, Cedric; Li, Ying; Summers, Scott A; Toh, Sue-Anne; Yassin, M Shabeer; Shabbir, Asim; Sheppard, Allan; Raghunath, Michael. ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs. Scientific Reports. 2016;6( 26883894):21173.  PubMed
Comments: IAC 3D culture
Machahua, Carlos; Montes-Worboys, Ana; Llatjos, Roger; Escobar, Ignacio; Dorca, Jordi; Molina-Molina, Maria; Vicens-Zygmunt, Vanesa. Increased AGE-RAGE ratio in idiopathic pulmonary fibrosis. Respiratory Research. 2016;17(1):144.  PubMed
Comments: IAC 3D culture
Piotrowski-Daspit, Alexandra S; Tien, Joe; Nelson, Celeste M. Interstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin. Integrative Biology : Quantitative Biosciences From Nano To Macro. 2016;8(3):319-31.  PubMed
Comments: IAC 3D culture
Gomes, Angélica Maciel; Bhat, Ramray; Correia, Ana Luísa; Mott, Joni D; Ilan, Neta; Vlodavsky, Israel; Pavão, Mauro S G; Bissell, Mina. Mammary Branching Morphogenesis Requires Reciprocal Signaling by Heparanase and MMP-14. Journal Of Cellular Biochemistry. 2015;116(8):1668-79.  PubMed
Comments: IAC 3D culture
Vicens-Zygmunt, Vanesa; Estany, Susanna; Colom, Adai; Montes-Worboys, Ana; Machahua, Carlos; Sanabria, Andrea Juliana; Llatjos, Roger; Escobar, Ignacio; Manresa, Frederic; Dorca, Jordi; Navajas, Daniel; Alcaraz, Jordi; Molina-Molina, Maria. Fibroblast viability and phenotypic changes within glycated stiffened three-dimensional collagen matrices. Respiratory Research. 2015;16(1):82.  PubMed
Comments: IAC 3D culture
Piotrowski, Alexandra S; Varner, Victor D; Gjorevski, Nikolce; Nelson, Celeste M. Three-dimensional traction force microscopy of engineered epithelial tissues. Methods In Molecular Biology (Clifton, N.j.). 1189( 25245695):191-206.  PubMed
Comments: IAC 3D culture
Colom, Adai; Galgoczy, Roland; Almendros, Isaac; Xaubet, Antonio; Farré, Ramon; Alcaraz, Jordi. Oxygen diffusion and consumption in extracellular matrix gels: implications for designing three-dimensional cultures. Journal Of Biomedical Materials Research. Part A. 2014;102(8):2776-84.  PubMed
Comments: IAC 3D culture
Galgoczy, Roland; Pastor, Isabel; Colom, Adai; Giménez, Alicia; Mas, Francesc; Alcaraz, Jordi. A spectrophotometer-based diffusivity assay reveals that diffusion hindrance of small molecules in extracellular matrix gels used in 3D cultures is dominated by viscous effects. Colloids And Surfaces. B, Biointerfaces. 2014;120( 24916283):200-7.  PubMed
Comments: IAC 3D culture
Okugawa, Yoji; Hirai, Yohei. A novel three-dimensional cell culture method to analyze epidermal cell differentiation in vitro. Methods In Molecular Biology (Clifton, N.j.). 1195( 24281867):183-90.  PubMed
Comments: IAC 3D culture
Pampaloni, Francesco; Berge, Ulrich; Marmaras, Anastasios; Horvath, Peter; Kroschewski, Ruth; Stelzer, Ernst H K. Tissue-culture light sheet fluorescence microscopy (TC-LSFM) allows long-term imaging of three-dimensional cell cultures under controlled conditions. Integrative Biology : Quantitative Biosciences From Nano To Macro. 2014;6(10):988-98.  PubMed
Comments: IAC 3D culture
Tashiro, Kanae; Shishido, Mayumi; Fujimoto, Keiko; Hirota, Yuko; Yo, Kazuyuki; Gomi, Takamasa; Tanaka, Yoshitaka. Age-related disruption of autophagy in dermal fibroblasts modulates extracellular matrix components. Biochemical And Biophysical Research Communications. 2014;443(1):167-72.  PubMed
Comments: IAC 3D culture
Correia, Ana Luísa; Mori, Hidetoshi; Chen, Emily I; Schmitt, Fernando C; Bissell, Mina J. The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90β. Genes & Development. 2013;27(7):805-17.  PubMed
Comments: IAC 3D culture
Mori, Hidetoshi; Lo, Alvin T; Inman, Jamie L; Alcaraz, Jordi; Ghajar, Cyrus M; Mott, Joni D; Nelson, Celeste M; Chen, Connie S; Zhang, Hui; Bascom, Jamie L; Seiki, Motoharu; Bissell, Mina J. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1. Development (Cambridge, England). 2013;140(2):343-52.  PubMed
Comments: IAC 3D culture
Okugawa, Yoji; Hirai, Yohei. Extracellular epimorphin modulates epidermal differentiation signals mediated by epidermal growth factor receptor. Journal Of Dermatological Science. 2013;69(3):236-42.  PubMed
Comments: IAC 3D culture
Hirokawa, Shigenari; Shimanuki, Tomomasa; Kitajima, Hiroyuki; Nishimori, Yasutomo; Shimosaka, Makoto. Knockdown of electron transfer flavoprotein β subunit reduced TGF-β-induced α-SMA mRNA expression but not COL1A1 in fibroblast-populated three-dimensional collagen gel cultures. Journal Of Dermatological Science. 2012;68(3):179-86.  PubMed
Comments: IAC 3D culture
Tien, Joe; Truslow, James G; Nelson, Celeste M. Modulation of invasive phenotype by interstitial pressure-driven convection in aggregates of human breast cancer cells. Plos One. 7(9):e45191.  PubMed
Comments: IAC 3D culture
Alcaraz, Jordi; Mori, Hidetoshi; Ghajar, Cyrus M; Brownfield, Doug; Galgoczy, Roland; Bissell, Mina J. Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening. Integrative Biology : Quantitative Biosciences From Nano To Macro. 2011;3(12):1153-66.  PubMed
Comments: IAC 3D culture
Andersen, Kristin; Mori, Hidetoshi; Fata, Jimmie; Bascom, Jamie; Oyjord, Tove; Mælandsmo, Gunhild M; Bissell, Mina. The metastasis-promoting protein S100A4 regulates mammary branching morphogenesis. Developmental Biology. 2011;352(2):181-90.  PubMed
Comments: IAC 3D culture
Hata, Yasuaki; Nakao, Shintaro; Kohno, Ri-Ichiro; Oba, Kumiyo; Kita, Takeshi; Miura, Muneki; Sassa, Yukio; Schering, Alexander; Ishibashi, Tatsuro. Role of tumour necrosis factor-α (TNFα) in the functional properties of hyalocytes. The British Journal Of Ophthalmology. 2011;95(2):261-5.  PubMed
Comments: IAC 3D culture
Hirokawa, Shigenari; Shimanuki, Tomomasa; Kitajima, Hiroyuki; Nishimori, Yasutomo; Shimosaka, Makoto. Identification of ETFB as a candidate protein that participates in the mechanoregulation of fibroblast cell number in collagen gel culture. Journal Of Dermatological Science. 2011;64(2):119-26.  PubMed
Comments: IAC 3D culture
Kawakami, Minoru; Umeda, Masafumi; Nakagata, Naomi; Takeo, Toru; Yamamura, Ken-Ichi. Novel migrating mouse neural crest cell assay system utilizing P0-Cre/EGFP fluorescent time-lapse imaging. Bmc Developmental Biology. 2011;11( 22070366):68.  PubMed
Comments: IAC 3D culture
Lee, Kangae; Gjorevski, Nikolce; Boghaert, Eline; Radisky, Derek C; Nelson, Celeste M. Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis. The Embo Journal. 2011;30(13):2662-74.  PubMed
Comments: IAC 3D culture
Pavlovich, Amira L; Boghaert, Eline; Nelson, Celeste M. Mammary branch initiation and extension are inhibited by separate pathways downstream of TGFβ in culture. Experimental Cell Research. 2011;317(13):1872-84.  PubMed
Comments: IAC 3D culture
Gjorevski, Nikolce; Nelson, Celeste M. Endogenous patterns of mechanical stress are required for branching morphogenesis. Integrative Biology : Quantitative Biosciences From Nano To Macro. 2010;2(9):424-34.  PubMed
Comments: IAC 3D culture
Okugawa, Yoji; Bascom, J Jamie; Hirai, Yohei. Epimorphin-derived peptide antagonists remedy epidermal parakeratosis triggered by unsaturated fatty acid. Journal Of Dermatological Science. 2010;59(3):176-83.  PubMed
Comments: IAC 3D culture
Pampaloni, Francesco; Stelzer, Ernst H K; Leicht, Stefan; Marcello, Marco. Madin-Darby canine kidney cells are increased in aerobic glycolysis when cultured on flat and stiff collagen-coated surfaces rather than in physiological 3-D cultures. Proteomics. 2010;10(19):3394-413.  PubMed
Comments: IAC 3D culture
Pavlovich, Amira L; Manivannan, Sriram; Nelson, Celeste M. Adipose stroma induces branching morphogenesis of engineered epithelial tubules. Tissue Engineering. Part A. 2010;16(12):3719-26.  PubMed
Comments: IAC 3D culture
Kanaho, Yoh-Ichiro; Enomoto, Masahiro; Endo, Daisuke; Maehiro, Sayaka; Park, Min Kyun; Murakami, Shizuko. Neurotrophic effect of gonadotropin-releasing hormone on neurite extension and neuronal migration of embryonic gonadotropin-releasing hormone neurons in chick olfactory nerve bundle culture. Journal Of Neuroscience Research. 2009;87(10):2237-44.  PubMed
Comments: IAC 3D culture
Kawahara, Shuhei; Hata, Yasuaki; Kita, Takeshi; Arita, Ryoichi; Miura, Muneki; Nakao, Shintaro; Mochizuki, Yasutaka; Enaida, Hiroshi; Kagimoto, Tadahisa; Goto, Yoshinobu; Hafezi-Moghadam, Ali; Ishibashi, Tatsuro. Potent inhibition of cicatricial contraction in proliferative vitreoretinal diseases by statins. Diabetes. 2008;57(10):2784-93.  PubMed
Comments: IAC 3D culture
Kim-Kaneyama, Joo-ri; Wachi, Nanae; Sata, Masataka; Enomoto, Soichiro; Fukabori, Kiyoko; Koh, Keitatsu; Shibanuma, Motoko; Nose, Kiyoshi. Hic-5, an adaptor protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo. Biochemical And Biophysical Research Communications. 2008;376(4):682-7.  PubMed
Comments: IAC 3D culture
Kita, Takeshi; Hata, Yasuaki; Arita, Ryoichi; Kawahara, Shuhei; Miura, Muneki; Nakao, Shintaro; Mochizuki, Yasutaka; Enaida, Hiroshi; Goto, Yoshinobu; Shimokawa, Hiroaki; Hafezi-Moghadam, Ali; Ishibashi, Tatsuro. Role of TGF-beta in proliferative vitreoretinal diseases and ROCK as a therapeutic target. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2008;105(45):17504-9.  PubMed
Comments: IAC 3D culture
Okugawa, Yoji; Hirai, Yohei. Overexpression of extracellular epimorphin leads to impaired epidermal differentiation in HaCaT keratinocytes. The Journal Of Investigative Dermatology. 2008;128(8):1884-93.  PubMed
Comments: IAC 3D culture
Hirai, Yohei; Nelson, Celeste M; Yamazaki, Kyoko; Takebe, Kyoko; Przybylo, Jennifer; Madden, Benjamin; Radisky, Derek C. Non-classical export of epimorphin and its adhesion to alphav-integrin in regulation of epithelial morphogenesis. Journal Of Cell Science. 2007;120(Pt 12):2032-43.  PubMed
Comments: IAC 3D culture
Kita, Takeshi; Hata, Yasuaki; Miura, Muneki; Kawahara, Shuhei; Nakao, Shintaro; Ishibashi, Tatsuro. Functional characteristics of connective tissue growth factor on vitreoretinal cells. Diabetes. 2007;56(5):1421-8.  PubMed
Comments: IAC 3D culture
Miura, Muneki; Hata, Yasuaki; Hirayama, Kumiko; Kita, Takeshi; Noda, Yoshihiro; Fujisawa, Kimihiko; Shimokawa, Hiroaki; Ishibashi, Tatsuro. Critical role of the Rho-kinase pathway in TGF-beta2-dependent collagen gel contraction by retinal pigment epithelial cells. Experimental Eye Research. 2006;82(5):849-59.  PubMed
Comments: IAC 3D culture
Yamanaka, Tomoyuki; Horikoshi, Yosuke; Izumi, Natsuko; Suzuki, Atsushi; Mizuno, Keiko; Ohno, Shigeo. Lgl mediates apical domain disassembly by suppressing the PAR-3-aPKC-PAR-6 complex to orient apical membrane polarity. Journal Of Cell Science. 2006;119(Pt 10):2107-18.  PubMed
Comments: IAC 3D culture
Abe, Masashi; Takahashi, Masaaki; Nagano, Akira. The effect of hyaluronic acid with different molecular weights on collagen crosslink synthesis in cultured chondrocytes embedded in collagen gels. Journal Of Biomedical Materials Research. Part A. 2005;75(2):494-9.  PubMed
Comments: IAC 3D culture
Fujita, Naoko; Nagata, Saburo. Repulsive guidance of axons of spinal sensory neurons in Xenopus laevis embryos: roles of Contactin and notochord-derived chondroitin sulfate proteoglycans. Development, Growth & Differentiation. 2005;47(7):445-56.  PubMed
Comments: IAC 3D culture
Hishikawa, Keiichi; Marumo, Takeshi; Miura, Shigeki; Nakanishi, Asato; Matsuzaki, Yumi; Shibata, Katsunori; Kohike, Hiroko; Komori, Takuya; Hayashi, Matsuhiko; Nakaki, Toshio; Nakauchi, Hiromitsu; Okano, Hideyuki; Fujita, Toshiro. Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16. Biochemical And Biophysical Research Communications. 2005;328(1):288-91.  PubMed
Comments: IAC 3D culture
Kagiyama, Yuka; Gotouda, Nanaka; Sakagami, Kiyo; Yasuda, Kunio; Mochii, Makoto; Araki, Masasuke. Extraocular dorsal signal affects the developmental fate of the optic vesicle and patterns the optic neuroepithelium. Development, Growth & Differentiation. 2005;47(8):523-36.  PubMed
Comments: IAC 3D culture
Kim-Kaneyama, Joo-ri; Suzuki, Wataru; Ichikawa, Kiyoko; Ohki, Takahiro; Kohno, Yoko; Sata, Masataka; Nose, Kiyoshi; Shibanuma, Motoko. Uni-axial stretching regulates intracellular localization of Hic-5 expressed in smooth-muscle cells in vivo. Journal Of Cell Science. 2005;118(Pt 5):937-49.  PubMed
Comments: IAC 3D culture
Kino-Oka, Masahiro; Yashiki, Shino; Ota, Yuka; Mushiaki, Yuko; Sugawara, Katsura; Yamamoto, Takeyuki; Takezawa, Toshiaki; Taya, Masahito. Subculture of chondrocytes on a collagen type I-coated substrate with suppressed cellular dedifferentiation. Tissue Engineering. 2005;11(3-4):597-608.  PubMed
Comments: IAC 3D culture
Yokoo, Naoki; Saito, Tomoyuki; Uesugi, Masaaki; Kobayashi, Naomi; Xin, Ke-Qin; Okuda, Kenji; Mizukami, Hiroaki; Ozawa, Keiya; Koshino, Tomihisa. Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector. Arthritis And Rheumatism. 2005;52(1):164-70.  PubMed
Comments: IAC 3D culture
Endo, Daisuke; Kogure, Kimitaka; Hasegawa, Yoshihisa; Maku-uchi, Masatoshi; Kojima, Itaru. Activin A augments vascular endothelial growth factor activity in promoting branching tubulogenesis in hepatic sinusoidal endothelial cells. Journal Of Hepatology. 2004;40(3):399-404.  PubMed
Comments: IAC 3D culture
Hirayama, Kumiko; Hata, Yasuaki; Noda, Yoshihiro; Miura, Muneki; Yamanaka, Ichiro; Shimokawa, Hiroaki; Ishibashi, Tatsuro. The involvement of the rho-kinase pathway and its regulation in cytokine-induced collagen gel contraction by hyalocytes. Investigative Ophthalmology & Visual Science. 2004;45(11):3896-903.  PubMed
Comments: IAC 3D culture
Fujitani, Masashi; Yamagishi, Satoru; Che, Yong Ho; Hata, Katsuhiko; Kubo, Tateki; Ino, Hidetoshi; Tohyama, Masaya; Yamashita, Toshihide. P311 accelerates nerve regeneration of the axotomized facial nerve. Journal Of Neurochemistry. 2004;91(3):737-44.  PubMed
Comments: IAC 3D culture
Minami, Takashi; Horiuchi, Keiko; Miura, Mai; Abid, Md Ruhul; Takabe, Wakako; Noguchi, Noriko; Kohro, Takahide; Ge, Xijin; Aburatani, Hiroyuki; Hamakubo, Takao; Kodama, Tatsuhiko; Aird, William C. Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis. The Journal Of Biological Chemistry. 2004;279(48):50537-54.  PubMed
Comments: IAC 3D culture
Kikuchi, Hiroshi; Suzuki, Keiko; Sakai, Nobuhiro; Yamada, Shoji. Odontoblasts induced from mesenchymal cells of murine dental papillae in three-dimensional cell culture. Cell And Tissue Research. 2004;317(2):173-85.  PubMed
Comments: IAC 3D culture
Minami, Takashi; Horiuchi, Keiko; Miura, Mai; Abid, Md Ruhul; Takabe, Wakako; Noguchi, Noriko; Kohro, Takahide; Ge, Xijin; Aburatani, Hiroyuki; Hamakubo, Takao; Kodama, Tatsuhiko; Aird, William C. Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis. The Journal Of Biological Chemistry. 2004;279(48):50537-54.  PubMed
Comments: IAC 3D culture
Minami, Takashi; Murakami, Takeshi; Horiuchi, Keiko; Miura, Mai; Noguchi, Tamio; Miyazaki, Jun-ichi; Hamakubo, Takao; Aird, William C; Kodama, Tatsuhiko. Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling. The Journal Of Biological Chemistry. 2004;279(20):20626-35.  PubMed
Comments: IAC 3D culture
Orban, Janine M; Wilson, Lorri B; Kofroth, Jessica A; El-Kurdi, Mohammed S; Maul, Timothy M; Vorp, David A. Crosslinking of collagen gels by transglutaminase. Journal Of Biomedical Materials Research. Part A. 2004;68(4):756-62.  PubMed
Comments: IAC 3D culture
Hecht, Iris; Cahalon, Liora; Hershkoviz, Rami; Lahat, Adi; Franitza, Suzanne; Lider, Ofer. Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: inhibition of cellular signaling, adhesion and chemotaxis. International Immunology. 2003;15(1):29-38.  PubMed
Comments: IAC 3D culture
Suzuki, Yasuhiro; Nakagomi, Saya; Namikawa, Kazuhiko; Kiryu-Seo, Sumiko; Inagaki, Naoyuki; Kaibuchi, Kozo; Aizawa, Hitoshi; Kikuchi, Kenjiro; Kiyama, Hiroshi. Collapsin response mediator protein-2 accelerates axon regeneration of nerve-injured motor neurons of rat. Journal Of Neurochemistry. 2003;86(4):1042-50.  PubMed
Comments: IAC 3D culture
Chaipinyo, Kanda; Oakes, Barry W; van Damme, Marie-Paule I. Effects of growth factors on cell proliferation and matrix synthesis of low-density, primary bovine chondrocytes cultured in collagen I gels. Journal Of Orthopaedic Research : Official Publication Of The Orthopaedic Research Society. 2002;20(5):1070-8.  PubMed
Comments: IAC 3D culture
Itoh, Takehiro; Kacchi, Masayuki; Abe, Hiroyuki; Sendai, Yutaka; Hoshi, Hiroyoshi. Growth, antrum formation, and estradiol production of bovine preantral follicles cultured in a serum-free medium. Biology Of Reproduction. 2002;67(4):1099-105.  PubMed
Comments: IAC 3D culture
Kondo, Takako; Ohta, Toshiro; Igura, Koichi; Hara, Yukihiko; Kaji, Kazuhiko. Tea catechins inhibit angiogenesis in vitro, measured by human endothelial cell growth, migration and tube formation, through inhibition of VEGF receptor binding. Cancer Letters. 2002;180(2):139-44.  PubMed
Comments: IAC 3D culture
Weaver, Valerie M; Lelièvre, Sophie; Lakins, Johnathon N; Chrenek, Micah A; Jones, Jonathan C R; Giancotti, Filippo; Werb, Zena; Bissell, Mina J. beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell. 2002;2(3):205-16.  PubMed
Comments: IAC 3D culture
Igura, K; Ohta, T; Kuroda, Y; Kaji, K. Resveratrol and quercetin inhibit angiogenesis in vitro. Cancer Letters. 2001;171(1):11-6.  PubMed
Comments: IAC 3D culture
Simian, M; Hirai, Y; Navre, M; Werb, Z; Lochter, A; Bissell, M J. The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells. Development (Cambridge, England). 2001;128(16):3117-31.  PubMed
Comments: IAC 3D culture
Takezawa, T; Inoue, M; Aoki, S; Sekiguchi, M; Wada, K; Anazawa, H; Hanai, N. Concept for organ engineering: a reconstruction method of rat liver for in vitro culture. Tissue Engineering. 2000;6(6):641-50.  PubMed
Comments: IAC 3D culture
Tanabe, K; Tachibana, T; Yamashita, T; Che, Y H; Yoneda, Y; Ochi, T; Tohyama, M; Yoshikawa, H; Kiyama, H. The small GTP-binding protein TC10 promotes nerve elongation in neuronal cells, and its expression is induced during nerve regeneration in rats. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience. 2000;20(11):4138-44.  PubMed
Comments: IAC 3D culture
Hirai, Y; Lochter, A; Galosy, S; Koshida, S; Niwa, S; Bissell, M J. Epimorphin functions as a key morphoregulator for mammary epithelial cells. The Journal Of Cell Biology. 1998;140(1):159-69.  PubMed
Comments: IAC 3D culture
Lelièvre, S A; Weaver, V M; Nickerson, J A; Larabell, C A; Bhaumik, A; Petersen, O W; Bissell, M J. Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus. Proceedings Of The National Academy Of Sciences Of The United States Of America. 1998;95(25):14711-6.  PubMed
Comments: IAC 3D culture
Matsusaki, M; Ochi, M; Uchio, Y; Shu, N; Kurioka, H; Kawasaki, K; Adachi, N. Effects of basic fibroblast growth factor on proliferation and phenotype expression of chondrocytes embedded in collagen gel. General Pharmacology. 1998;31(5):759-64.  PubMed
Comments: IAC 3D culture
Hirota, H; Kiyama, H; Kishimoto, T; Taga, T. Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma. The Journal Of Experimental Medicine. 1996;183(6):2627-34.  PubMed
Comments: IAC 3D culture
Laoide, B M; Courty, Y; Gastinne, I; Thibaut, C; Kellermann, O; Rougeon, F. Immortalised mouse submandibular epithelial cell lines retain polarised structural and functional properties. Journal Of Cell Science. 1996;109 ( Pt 12)( 9013327):2789-800.  PubMed
Comments: IAC 3D culture
Kobayashi, S; Miyamoto, T; Kimura, I; Kimura, M. Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro. Biological & Pharmaceutical Bulletin. 1995;18(10):1382-6.  PubMed
Comments: IAC 3D culture
Song, Xiaoyu; Nihashi, Yuma; Imai, Yukiko; Mori, Nobuhito; Kagaya, Noritaka; Suenaga, Hikaru; Shin-Ya, Kazuo; Yamamoto, Masamichi; Setoyama, Daiki; Kunisaki, Yuya; Kida, Yasuyuki S. Collagen Lattice Model, Populated with Heterogeneous Cancer-Associated Fibroblasts, Facilitates Advanced Reconstruction of Pancreatic Cancer Microenvironment. International Journal Of Molecular Sciences. 2024;25(7)  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Inagaki, Satoshi; Morimoto, Yuya; Suzuki, Ikuo K; Emoto, Kazuo; Takeuchi, Shoji. Co-culture system of human skin equivalents with mouse neural spheroids. Journal Of Bioscience And Bioengineering. 2023;136(3):239-245.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Kasahara, Keitaro; Muramatsu, Jumpei; Kurashina, Yuta; Miura, Shigenori; Miyata, Shogo; Onoe, Hiroaki. Spatiotemporal single-cell tracking analysis in 3D tissues to reveal heterogeneous cellular response to mechanical stimuli. Science Advances. 2023;9(41):eadf9917.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Dance, Yoseph W; Obenreder, Mackenzie C; Seibel, Alex J; Meshulam, Tova; Ogony, Joshua W; Lahiri, Nikhil; Pacheco-Spann, Laura; Radisky, Derek C; Layne, Matthew D; Farmer, Stephen R; Nelson, Celeste M; Tien, Joe. Adipose Cells Induce Escape from an Engineered Human Breast Microtumor Independently of their Obesity Status. Cellular And Molecular Bioengineering. 2023;16(1):23-39.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Machahua, Carlos; Vicens-Zygmunt, Vanesa; Ríos-Martín, Jesús; Llatjós, Roger; Escobar-Campuzano, Ignacio; Molina-Molina, María; Montes-Worboys, Ana. Collagen 3D matrices as a model for the study of cell behavior in pulmonary fibrosis. Experimental Lung Research. 2022;48(3):126-136.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Seibel, Alex J; Kelly, Owen M; Dance, Yoseph W; Nelson, Celeste M; Tien, Joe. Role of Lymphatic Endothelium in Vascular Escape of Engineered Human Breast Microtumors. Cellular And Molecular Bioengineering. 2022;15(6):553-569.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Mori, Nobuhito; Kida, Yasuyuki S. Applicability of Artificial Vascularized Liver Tissue to Proteomic Analysis. Micromachines. 2021;12(4)  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Ota, Yukiko; Yoshida, Hiroyuki; Endo, Yoko; Sayo, Tetsuya; Takahashi, Yoshito. A Connecting Link between Hyaluronan Synthase 3-Mediated Hyaluronan Production and Epidermal Function. International Journal Of Molecular Sciences. 2022;23(5)  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Dance, Yoseph W; Meshulam, Tova; Seibel, Alex J; Obenreder, Mackenzie C; Layne, Matthew D; Nelson, Celeste M; Tien, Joe. Adipose Stroma Accelerates the Invasion and Escape of Human Breast Cancer Cells from an Engineered Microtumor. Cellular And Molecular Bioengineering. 2022;15(1):15-29.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Endo, Yoko; Yoshida, Hiroyuki; Ota, Yukiko; Akazawa, Yumiko; Sayo, Tetsuya; Hanai, Ushio; Imagawa, Kotaro; Sasaki, Masashi; Takahashi, Yoshito. Accelerated human epidermal turnover driven by increased hyaluronan production. Journal Of Dermatological Science. 2021;101(2):123-133.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Morikura, Takashi; Miyata, Shogo. Mechanical Intermittent Compression Affects the Progression Rate of Malignant Melanoma Cells in a Cycle Period-Dependent Manner. Diagnostics (Basel, Switzerland). 2021;11(6)  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Uetsuki, Ryo; Higashikawa, Koichiro; Okuda, Satoshi; Yamakado, Nao; Ishida, Fumi; Rizqiawan, Andra; Ono, Shigehiro; Takechi, Masaaki; Mizuta, Kuniko; Shigeishi, Hideo; Kamata, Nobuyuki; Tobiume, Kei. The squamous cell carcinoma cell line OM-1 retains both p75-dependent stratified epithelial progenitor potential and cancer stem cell properties. Biochemistry And Biophysics Reports. 2021;26( 34041369):101003.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Sharma, Kunal; Thacker, Vivek V; Dhar, Neeraj; Clapés Cabrer, Maria; Dubois, Anaëlle; Signorino-Gelo, François; Mullenders, Jasper; Knott, Graham W; Clevers, Hans; McKinney, John D. Early invasion of the bladder wall by solitary bacteria protects UPEC from antibiotics and neutrophil swarms in an organoid model. Cell Reports. 2021;36(3):109351.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Kimura, Shun; Tsuchiya, Ayako; Ogawa, Miho; Ono, Miki; Suda, Nao; Sekimoto, Kaori; Takeo, Makoto; Tsuji, Takashi. Tissue-scale tensional homeostasis in skin regulates structure and physiological function. Communications Biology. 2020;3(1):637.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Miyazaki, Kaoru; Togo, Shinsaku; Okamoto, Reiko; Idiris, Alimjan; Kumagai, Hiromichi; Miyagi, Yohei. Collective cancer cell invasion in contact with fibroblasts through integrin-α5β1/fibronectin interaction in collagen matrix. Cancer Science. 2020;111(12):4381-4392.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Mori, Nobuhito; Kida, Yasuyuki S. Expression of genes involved in drug metabolism differs between perfusable 3D liver tissue and conventional 2D-cultured hepatocellular carcinoma cells. Febs Open Bio. 2020;10(10):1985-2002.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Mori, Nobuhito; Akagi, Yuka; Imai, Yukiko; Takayama, Yuzo; Kida, Yasuyuki S. Fabrication of Perfusable Vascular Channels and Capillaries in 3D Liver-like Tissue. Scientific Reports. 2020;10(1):5646.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Miyazaki, Kaoru; Oyanagi, Jun; Hoshino, Daisuke; Togo, Shinsaku; Kumagai, Hiromichi; Miyagi, Yohei. Cancer cell migration on elongate protrusions of fibroblasts in collagen matrix. Scientific Reports. 2019;9(1):292.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Muraguchi, Taichi; Nanba, Daisuke; Nishimura, Emi K; Tashiro, Tomoko. IGF-1R deficiency in human keratinocytes disrupts epidermal homeostasis and stem cell maintenance. Journal Of Dermatological Science. 2019;94(2):298-305.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Akimoto, Naonari; Nakamura, Kodai; Hijioka, Hiroshi; Kume, Kenichi; Matsumura, Yoshiaki; Sugiura, Tsuyoshi. Transfection of T-Box Transcription Factor BRACHYURY and SOX2 Synergistically Promote Self-Renewal and Invasive Phenotype in Oral Cancer Cells. International Journal Of Molecular Sciences. 2018;19(11)  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Matsuura-Hachiya, Yuko; Arai, Koji Y; Muraguchi, Taichi; Sasaki, Tasuku; Nishiyama, Toshio. Type IV collagen aggregates promote keratinocyte proliferation and formation of epidermal layer in human skin equivalents. Experimental Dermatology. 2018;27(5):443-448.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Mori, Nobuhito; Morimoto, Yuya; Takeuchi, Shoji. Perfusable and stretchable 3D culture system for skin-equivalent. Biofabrication. 2018;11(1):011001.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Pham, Trung Quang; Kawaue, Takumi; Hoshi, Takayuki; Tanaka, Yoshihiro; Miyata, Takaki; Sano, Akihito. Role of extrinsic mechanical force in the development of the RA-I tactile mechanoreceptor. Scientific Reports. 2018;8(1):11085.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Sakamoto, Naoya; Ueki, Yosuke; Oi, Masaki; Kiuchi, Takuya; Sato, Masaaki. Fluid shear stress suppresses ICAM-1-mediated transendothelial migration of leukocytes in coculture model. Biochemical And Biophysical Research Communications. 2018;502(3):403-408.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Mori, Nobuhito; Morimoto, Yuya; Takeuchi, Shoji. Skin integrated with perfusable vascular channels on a chip. Biomaterials. 2017;116( 27914266):48-56.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Uehara, Kazuki; Hara, Masao; Matsuo, Toshiki; Namiki, Go; Watanabe, Mutsuto; Nomura, Yoshihiro. Hyaluronic acid secretion by synoviocytes alters under cyclic compressive load in contracted collagen gels. Cytotechnology. 2015;67(1):19-26.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Arai, Koji Y; Fujioka, Atsuko; Okamura, Ryoko; Nishiyama, Toshio. Stimulatory effect of fibroblast-derived prostaglandin E₂ on keratinocyte stratification in the skin equivalent. Wound Repair And Regeneration : Official Publication Of The Wound Healing Society [And] The European Tissue Repair Society. 2014;22(6):701-11.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Arai, Koji Y; Sugimoto, Mami; Ito, Kanako; Ogura, Yuki; Akutsu, Nobuko; Amano, Satoshi; Adachi, Eijiro; Nishiyama, Toshio. Repeated folding stress-induced morphological changes in the dermal equivalent. Skin Research And Technology : Official Journal Of International Society For Bioengineering And The Skin (Isbs) [And] International Society For Digital Imaging Of Skin (Isdis) [And] International Society For Skin Imaging (Issi). 2014;20(4):399-408.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Hara, Masao; Nakashima, Masahiro; Fujii, Takahiro; Uehara, Kazuki; Yokono, Chisako; Hashizume, Ron; Nomura, Yoshihiro. Construction of collagen gel scaffolds for mechanical stress analysis. Bioscience, Biotechnology, And Biochemistry. 78(3):458-61.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Rizqiawan, Andra; Tobiume, Kei; Okui, Gaku; Yamamoto, Kazuhiro; Shigeishi, Hideo; Ono, Shigehiro; Shimasue, Hiroshi; Takechi, Masaaki; Higashikawa, Koichiro; Kamata, Nobuyuki. Autocrine galectin-1 promotes collective cell migration of squamous cell carcinoma cells through up-regulation of distinct integrins. Biochemical And Biophysical Research Communications. 2013;441(4):904-10.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Shimizu, Kazuya; Chiba, Sachie; Hori, Yuichi. Identification of a novel subpopulation of tumor-initiating cells from gemcitabine-resistant pancreatic ductal adenocarcinoma patients. Plos One. 8(11):e81283.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Arai, Koji Y; Ono, Mariko; Kudo, Chikako; Fujioka, Atsuko; Okamura, Ryoko; Nomura, Yoshihiro; Nishiyama, Toshio. IL-1beta stimulates activin betaA mRNA expression in human skin fibroblasts through the MAPK pathways, the nuclear factor-kappaB pathway, and prostaglandin E2. Endocrinology. 2011;152(10):3779-90.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Murakami, Shizuko; Ohki-Hamazaki, Hiroko; Watanabe, Keisuke; Ikenaka, Kazuhiro; Ono, Katsuhiko. Netrin 1 provides a chemoattractive cue for the ventral migration of GnRH neurons in the chick forebrain. The Journal Of Comparative Neurology. 2010;518(11):2019-34.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Higashikawa, Koichiro; Yoneda, Shingo; Tobiume, Kei; Saitoh, Masao; Taki, Masayuki; Mitani, Yoshitsugu; Shigeishi, Hideo; Ono, Shigehiro; Kamata, Nobuyuki. DeltaNp63alpha-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma. International Journal Of Cancer. 2009;124(12):2837-44.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Sharp, T; Kingston, J; Grahame-Smith, D G. Repeated ECS enhances dopamine D-1 but not D-2 agonist-induced behavioural responses in rats. Psychopharmacology. 100(1):110-4.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Azuma, Chinatsu; Tohyama, Harukazu; Nakamura, Hideki; Kanaya, Fuminori; Yasuda, Kazunori. Antibody neutralization of TGF-beta enhances the deterioration of collagen fascicles in a tissue-cultured tendon matrix with ex vivo fibroblast infiltration. Journal Of Biomechanics. 40(10):2184-90.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Higashikawa, Koichiro; Yoneda, Shingo; Tobiume, Kei; Taki, Masayuki; Shigeishi, Hideo; Kamata, Nobuyuki. Snail-induced down-regulation of DeltaNp63alpha acquires invasive phenotype of human squamous cell carcinoma. Cancer Research. 2007;67(19):9207-13.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Ikema, Yasunari; Tohyama, Harukazu; Yamamoto, Ei; Kanaya, Fuminori; Yasuda, Kazunori. Ex vivo infiltration of fibroblasts into the tendon deteriorates the mechanical properties of tendon fascicles but not those of tendon bundles. Clinical Biomechanics (Bristol, Avon). 2007;22(1):120-6.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Noguchi, Chika; Umino, Takeshi; Miyazaki, Yasunari; Jinta, Torahiko; Usui, Yutaka; Yoshizawa, Yasuyuki. TGF-beta and glutathione promote tissue repair in cigarette smoke induced injury. Journal Of Medical And Dental Sciences. 2007;54(1):109-16.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Yaguchi, Yuichiro; Wada, Kota; Uchimizu, Hirotaka; Tanaka, Yasuhiro; Kojima, Hiromi; Moriyama, Hiroshi. Middle ear mucosa regeneration by grafting of artificial mucosa. Acta Oto-Laryngologica. 2007;127(10):1038-44.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Hirai, Kazuya; Kikuchi, Shiro; Kurita, Astushi; Ohashi, Shihoka; Adachi, Eijiro; Matsuoka, Yasuhiro; Nagata, Kazuhiro; Watanabe, Masahiko. Immunohistochemical distribution of heat shock protein 47 (HSP47) in scirrhous carcinoma of the stomach. Anticancer Research. 2006;26(1A):71-8.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Wada, Kota; Tanaka, Yasuhiro; Kojima, Hiromi; Inamatsu, Mutsumi; Yoshizato, Katsutoshi; Moriyama, Hiroshi. In vitro reconstruction of a three-dimensional middle ear mucosal organ and its in vivo transplantation. Acta Oto-Laryngologica. 2006;126(8):801-10.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Ikema, Y; Tohyama, H; Nakamura, H; Kanaya, F; Yasuda, K. Growth kinetics and integrin expression of fibroblasts infiltrating devitalised patellar tendons are different from those of intrinsic fibroblasts. The Journal Of Bone And Joint Surgery. British Volume. 2005;87(12):1689-93.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Tanaka, Yasuhiro; Yaguchi, Yuichiro; Wada, Kota; Kojima, Hiromi; Moriyama, Hiroshi. Creation of a cholesteatoma model using three-dimensional cultured skin equivalents. The Laryngoscope. 2005;115(8):1421-7.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Miyashita, H; Hakamata, Y; Kobayashi, E; Kobayashi, K. Characterization of hair follicles induced in implanted, cultured rat keratinocyte sheets. Experimental Dermatology. 2004;13(8):491-8.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Berry, Catherine C; Shelton, Julia C; Bader, Dan L; Lee, David A. Influence of external uniaxial cyclic strain on oriented fibroblast-seeded collagen gels. Tissue Engineering. 2003;9(4):613-24.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Kikuchi, Kaoru; Kishino, Akiyoshi; Konishi, Osamu; Kumagai, Kazuo; Hosotani, Nobuo; Saji, Ikutaro; Nakayama, Chikao; Kimura, Toru. In vitro and in vivo characterization of a novel semaphorin 3A inhibitor, SM-216289 or xanthofulvin. The Journal Of Biological Chemistry. 2003;278(44):42985-91.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Hubert, P; van den Brüle, F; Giannini, S L; Franzen-Detrooz, E; Boniver, J; Delvenne, P. Colonization of in vitro-formed cervical human papillomavirus- associated (pre)neoplastic lesions with dendritic cells: role of granulocyte/macrophage colony-stimulating factor. The American Journal Of Pathology. 1999;154(3):775-84.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Sato, A; Hamazaki, T; Oomura, T; Osada, H; Kakeya, M; Watanabe, M; Nakamura, T; Nakamura, Y; Koshikawa, N; Yoshizaki, I; Aizawa, S; Yoda, S; Ogiso, A; Takaoki, M; Kohno, Y; Tanaka, H. Effects of microgravity on c-fos gene expression in osteoblast-like MC3T3-E1 cells. Advances In Space Research : The Official Journal Of The Committee On Space Research (Cospar). 24(6):807-13.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Furuyama, A; Kimata, K; Mochitate, K. Assembly of basement membrane in vitro by cooperation between alveolar epithelial cells and pulmonary fibroblasts. Cell Structure And Function. 1997;22(6):603-14.  PubMed
Comments: I-AC co-culture, Mechanical stress culture
Ashimori, Atsushige; Higashijima, Fumiaki; Ogata, Tadahiko; Sakuma, Ayano; Hamada, Waka; Sunada, Junki; Aoki, Ren; Mikuni, Masanori; Hayashi, Ken'ichiro; Wakuta, Makiko; Yoshimoto, Takuya; Minamoto, Akira; Ko, Ji-Ae; Kimura, Kazuhiro. HIF-1α-dependent upregulation of angiogenic factors by mechanical stimulation in retinal pigment epithelial cells. Disease Models & Mechanisms. 2024;17(4)  PubMed
Comments: I-AC coating
Hirukawa, Kazuya; Yagi, Hiroshi; Kuroda, Kohei; Watanabe, Masafumi; Nishi, Kotaro; Nagata, Shogo; Abe, Yuta; Kitago, Minoru; Adachi, Shungo; Sudo, Ryo; Kitagawa, Yuko. Novel approach for reconstruction of the three-dimensional biliary system in decellularized liver scaffold using hepatocyte progenitors. Plos One. 19(2):e0297285.  PubMed
Comments: I-AC coating
Hori, Takeshi; Okae, Hiroaki; Shibata, Shun; Kobayashi, Norio; Kobayashi, Eri H; Oike, Akira; Sekiya, Asato; Arima, Takahiro; Kaji, Hirokazu. Trophoblast stem cell-based organoid models of the human placental barrier. Nature Communications. 2024;15(1):962.  PubMed
Comments: I-AC coating
Ogawa, Shuhei; Ishii, Takashi; Otani, Takahito; Inai, Yuko; Matsuura, Takashi; Inai, Tetsuichiro. JNK inhibition enhances cell-cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes. Histochemistry And Cell Biology. 2024;161(4):345-357.  PubMed
Comments: I-AC coating
Tatsuno, Rikito; Ichikawa, Jiro; Komohara, Yoshihiro; Pan, Cheng; Kawasaki, Tomonori; Enomoto, Atsushi; Aoki, Kaoru; Hayakawa, Keiko; Iwata, Shintaro; Jubashi, Takahiro; Haro, Hirotaka. Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway. Cell Death & Disease. 2024;15(2):108.  PubMed
Comments: I-AC coating
Karanfil, Aslı Sena; Louis, Fiona; Sowa, Yoshihiro; Matsusaki, Michiya. ECM proteins and cationic polymers coating promote dedifferentiation of patient-derived mature adipocytes to stem cells. Biomaterials Science. 2023;11(23):7623-7638.  PubMed
Comments: I-AC coating
Kim, Mee-Hae; Tan, Shao Ying; Yamahara, Kenichi; Kino-Oka, Masahiro. An in vitro culture platform to study the extracellular matrix remodeling potential of human mesenchymal stem cells. Acta Biomaterialia. 2023;170( 37619896):376-388.  PubMed
Comments: I-AC coating
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Itoh, Kohji; Satoh, Yurie; Kadota, Yoshito; Oheda, Yukako; Kuwahara, Jun; Shimmoto, Michie; Sakuraba, Hitoshi. Expression of lysosomal protective protein/cathepsin A in a stably transformed human neuroblastoma cell line during bi-directional differentiation into neuronal and Schwannian cells. Neurochemistry International. 2004;44(6):447-57.  PubMed
Comments: I-AC coating
Gotoh, Yohko; Niimi, Shingo; Hayakawa, Takao; Miyashita, Tokuji. Preparation of lactose-silk fibroin conjugates and their application as a scaffold for hepatocyte attachment. Biomaterials. 2004;25(6):1131-40.  PubMed
Comments: I-AC coating
Kariya, Yoshinobu; Miyazaki, Kaoru. The basement membrane protein laminin-5 acts as a soluble cell motility factor. Experimental Cell Research. 2004;297(2):508-20.  PubMed
Comments: I-AC coating
Kawamura, Kazuhiro; Takano, Kazunori; Suetsugu, Shiro; Kurisu, Shusaku; Yamazaki, Daisuke; Miki, Hiroaki; Takenawa, Tadaomi; Endo, Takeshi. N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factor. The Journal Of Biological Chemistry. 2004;279(52):54862-71.  PubMed
Comments: I-AC coating
Kim, Sang-Heon; Hoshiba, Takashi; Akaike, Toshihiro. Hepatocyte behavior on synthetic glycopolymer matrix: inhibitory effect of receptor-ligand binding on hepatocyte spreading. Biomaterials. 2004;25(10):1813-23.  PubMed
Comments: I-AC coating
Satoh, Yurie; Kadota, Yoshito; Oheda, Yukako; Kuwahara, Jun; Aikawa, Seiichi; Matsuzawa, Fumiko; Doi, Hirofumi; Aoyagi, Takaaki; Sakuraba, Hitoshi; Itoh, Kohji. Microbial serine carboxypeptidase inhibitors--comparative analysis of actions on homologous enzymes derived from man, yeast and wheat. The Journal Of Antibiotics. 2004;57(5):316-25.  PubMed
Comments: I-AC coating
Takashima, Seiji; Ise, Hirohiko; Zhao, Peng; Akaike, Toshihiro; Nikaido, Toshio. Human amniotic epithelial cells possess hepatocyte-like characteristics and functions. Cell Structure And Function. 2004;29(3):73-84.  PubMed
Comments: I-AC coating
Pang, Tianxiang; Wakabayashi, Shigeo; Shigekawa, Munekazu. Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger. The Journal Of Biological Chemistry. 2002;277(46):43771-7.  PubMed
Comments: I-AC coating
Ito, T; Yasui, K; Mukaigawa, J; Katsume, A; Kohara, M; Mitamura, K. Acquisition of susceptibility to hepatitis C virus replication in HepG2 cells by fusion with primary human hepatocytes: establishment of a quantitative assay for hepatitis C virus infectivity in a cell culture system. Hepatology (Baltimore, Md.). 2001;34(3):566-72.  PubMed
Comments: I-AC coating
Imaizumi, K; Tsuda, M; Imai, Y; Wanaka, A; Takagi, T; Tohyama, M. Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death. The Journal Of Biological Chemistry. 1997;272(30):18842-8.  PubMed
Comments: I-AC coating
Saito, Y; Tsubuki, S; Ito, H; Kawashima, S. Possible involvement of a novel protease in neurite outgrowth of PC12 cells. Neuroscience Research. Supplement : The Official Journal Of The Japan Neuroscience Society. 13( 2088345):S97-101.  PubMed
Comments: I-AC coating
Hamilton, Nick J I; Tait, Angela; Weil, Ben; Daniels, Julie. The Use of a Dehydrated Cellularized Collagen Matrix to Replace Fibrotic Vocal Fold Mucosa. The Laryngoscope. 2024;134(2):882-893.  PubMed
Comments: I-AC fabricating/coating scaffold
Mashiyama, Shota; Hemmi, Runa; Sato, Takeru; Kato, Atsuya; Taniguchi, Tatsuo; Yamada, Masumi. Pushing the limits of microfluidic droplet production efficiency: engineering microchannels with seamlessly implemented 3D inverse colloidal crystals. Lab On A Chip. 2024;24(2):171-181.  PubMed
Comments: I-AC fabricating/coating scaffold
Song, Young Woo; Maekawa, Shogo; Sasaki, Keito; Yoshida, Daichi; Nagai, Masazumi; Ishikawa-Nagai, Shigemi; Da Silva, John; Kim, David Minjoon; Chen, Chia-Yu. Microscopic in-situ analysis of the mucosal healing around implants treated by protease activated receptor 4-agonist peptide or perpendicularly protruded type I collagen in rats. Journal Of Biomedical Materials Research. Part B, Applied Biomaterials. 2024;112(1):e35330.  PubMed
Comments: I-AC fabricating/coating scaffold
Kurashina, Yuta; Fukada, Keisuke; Itai, Shun; Akizuki, Shuichi; Sato, Ryo; Masuda, Akari; Tani, Hidenori; Fujita, Jun; Fukuda, Keiichi; Tohyama, Shugo; Onoe, Hiroaki. Hydrogel-Sheathed hiPSC-Derived Heart Microtissue Enables Anchor-Free Contractile Force Measurement. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 2023;10(35):e2301831.  PubMed
Comments: I-AC fabricating/coating scaffold
Takeya, Hiroaki; Itai, Shun; Kimura, Hiroo; Kurashina, Yuta; Amemiya, Tsuyoshi; Nagoshi, Narihito; Iwamoto, Takuji; Sato, Kazuki; Shibata, Shinsuke; Matsumoto, Morio; Onoe, Hiroaki; Nakamura, Masaya. Schwann cell-encapsulated chitosan-collagen hydrogel nerve conduit promotes peripheral nerve regeneration in rodent sciatic nerve defect models. Scientific Reports. 2023;13(1):11932.  PubMed
Comments: I-AC fabricating/coating scaffold
Hiroshima, Yuya; Oyama, Yuki; Sawasaki, Kaoru; Nakamura, Masanori; Kimura, Naoyuki; Kawahito, Koji; Fujie, Hiromichi; Sakamoto, Naoya. A Compressed Collagen Construct for Studying Endothelial-Smooth Muscle Cell Interaction Under High Shear Stress. Annals Of Biomedical Engineering. 2022;50(8):951-963.  PubMed
Comments: I-AC fabricating/coating scaffold
Itai, Shun; Onoe, Hiroaki. Flexibly Deformable Collagen Hydrogel Tube Reproducing Immunological Tissue Deformation of Blood Vessels as a Pharmacokinetic Testing Model. Advanced Healthcare Materials. 2022;11(1):e2101509.  PubMed
Comments: I-AC fabricating/coating scaffold
Jo, Byeongwook; Morimoto, Yuya; Takeuchi, Shoji. Skeletal muscle-adipose cocultured tissue fabricated using cell-laden microfibers and a hydrogel sheet. Biotechnology And Bioengineering. 2022;119(2):636-643.  PubMed
Comments: I-AC fabricating/coating scaffold
Kalaimani, Lavanya; Devarajan, Bharanidharan; Namperumalsamy, Venkatesh Prajna; Veerappan, Muthukkaruppan; Daniels, Julie T; Chidambaranathan, Gowri Priya. Hsa-miR-150-5p inhibits Wnt-β-catenin signaling in human corneal epithelial stem cells. Molecular Vision. 28( 36274818):178-191.  PubMed
Comments: I-AC fabricating/coating scaffold
Kalaimani, Lavanya; Devarajan, Bharanidharan; Namperumalsamy, Venkatesh Prajna; Veerappan, Muthukkaruppan; Daniels, Julie T; Chidambaranathan, Gowri Priya. Hsa-miR-143-3p inhibits Wnt-β-catenin and MAPK signaling in human corneal epithelial stem cells. Scientific Reports. 2022;12(1):11432.  PubMed
Comments: I-AC fabricating/coating scaffold
Maeda, Eijiro; Kawamura, Ryota; Suzuki, Takashi; Matsumoto, Takeo. Rapid fabrication of tendon-like collagen gel via simultaneous fibre alignment and intermolecular cross-linking under mechanical loading. Biomedical Materials (Bristol, England). 2022;17(4)  PubMed
Comments: I-AC fabricating/coating scaffold
Mazari-Arrighi, Elsa; Okitsu, Teru; Teramae, Hiroki; Aoyagi, Hoshimi; Kiyosawa, Mahiro; Yano, Mariko; Chatelain, François; Fuchs, Alexandra; Takeuchi, Shoji. In vitro proliferation and long-term preservation of functional primary rat hepatocytes in cell fibers. Scientific Reports. 2022;12(1):8813.  PubMed
Comments: I-AC fabricating/coating scaffold
Morita, Akihiro; Yamada, Masumi; Utoh, Rie; Momiyama, Kanta; Iwadate, Hideki; Seki, Minoru. Formation of 3D tissues of primary hepatocytes using fibrillized collagen microparticles as intercellular binders. Journal Of Bioscience And Bioengineering. 2022;133(3):265-272.  PubMed
Comments: I-AC fabricating/coating scaffold
Wang, Yue; Kanie, Kei; Takezawa, Toshiaki; Horikawa, Miki; Kaneko, Kyoshiro; Sugimoto, Ayako; Yamawaki-Ogata, Aika; Narita, Yuji; Kato, Ryuji. Bi-layered carboxymethyl cellulose-collagen vitrigel dual-surface adhesion-prevention membrane. Carbohydrate Polymers. 2022;285( 35287853):119223.  PubMed
Comments: I-AC fabricating/coating scaffold
Yamada, Masahiro; Kimura, Tsuyoshi; Nakamura, Naoko; Watanabe, Jun; Kartikasari, Nadia; He, Xindie; Tiskratok, Watcharaphol; Yoshioka, Hayato; Shinno, Hidenori; Egusa, Hiroshi. Titanium Nanosurface with a Biomimetic Physical Microenvironment to Induce Endogenous Regeneration of the Periodontium. Acs Applied Materials & Interfaces. 2022;14(24):27703-27719.  PubMed
Comments: I-AC fabricating/coating scaffold
Nagayama, Kazuaki. A Loss of Nuclear-Cytoskeletal Interactions in Vascular Smooth Muscle Cell Differentiation Induced by a Micro-Grooved Collagen Substrate Enabling the Modeling of an In Vivo Cell Arrangement. Bioengineering (Basel, Switzerland). 2021;8(9)  PubMed
Comments: I-AC fabricating/coating scaffold
Nie, Minghao; Shima, Ai; Fukushima, Kenta; Morimoto, Yuya; Takeuchi, Shoji. A Cylindrical Molding Method for the Biofabrication of Plane-Shaped Skeletal Muscle Tissue. Micromachines. 2021;12(11)  PubMed
Comments: I-AC fabricating/coating scaffold
Song, Qin; Iku, Shouhei; Sammons, Rachel; Yagami, Kimitoshi; Furusawa, Toshitake; Morimoto, Koichi; Rahaman, Md Shiblur; Kurasaki, Masaaki; Tokura, Seiichi; Kuboki, Yoshinori. Binding of collagen gene products with titanium oxide. Journal Of Biochemistry. 2021;169(5):565-573.  PubMed
Comments: I-AC fabricating/coating scaffold
Utoh, Rie; Enomoto, Sakiko; Yamada, Masumi; Yamanaka, Keigo; Yajima, Yuya; Furusawa, Kazuya; Seki, Minoru. Polyanion-induced, microfluidic engineering of fragmented collagen microfibers for reconstituting extracellular environments of 3D hepatocyte culture. Materials Science & Engineering. C, Materials For Biological Applications. 2021;129( 34579926):112417.  PubMed
Comments: I-AC fabricating/coating scaffold
Varma, Ratna; Marin-Araujo, Alba E; Rostami, Sara; Waddell, Thomas K; Karoubi, Golnaz; Haykal, Siba. Short-Term Preclinical Application of Functional Human Induced Pluripotent Stem Cell-Derived Airway Epithelial Patches. Advanced Healthcare Materials. 2021;10(21):e2100957.  PubMed
Comments: I-AC fabricating/coating scaffold
Zemmyo, Daiki; Yamamoto, Masashi; Miyata, Shogo. Efficient Decellularization by Application of Moderate High Hydrostatic Pressure with Supercooling Pretreatment. Micromachines. 2021;12(12)  PubMed
Comments: I-AC fabricating/coating scaffold
Chen, Yazhou; Lee, Kyubae; Yang, Yingnan; Kawazoe, Naoki; Chen, Guoping. PLGA-collagen-ECM hybrid meshes mimicking stepwise osteogenesis and their influence on the osteogenic differentiation of hMSCs. Biofabrication. 2020;12(2):025027.  PubMed
Comments: I-AC fabricating/coating scaffold
Itai, Shun; Suzuki, Karin; Kurashina, Yuta; Kimura, Hiroo; Amemiya, Tsuyoshi; Sato, Kazuki; Nakamura, Masaya; Onoe, Hiroaki. Cell-encapsulated chitosan-collagen hydrogel hybrid nerve guidance conduit for peripheral nerve regeneration. Biomedical Microdevices. 2020;22(4):81.  PubMed
Comments: I-AC fabricating/coating scaffold
Nikolaev, Mikhail; Mitrofanova, Olga; Broguiere, Nicolas; Geraldo, Sara; Dutta, Devanjali; Tabata, Yoji; Elci, Bilge; Brandenberg, Nathalie; Kolotuev, Irina; Gjorevski, Nikolce; Clevers, Hans; Lutolf, Matthias P. Homeostatic mini-intestines through scaffold-guided organoid morphogenesis. Nature. 2020;585(7826):574-578.  PubMed
Comments: I-AC fabricating/coating scaffold
Duong, Van Thuy; Dang, Thi Thao; Hwang, Chang Ho; Back, Sung Hoon; Koo, Kyo-In. Coaxial printing of double-layered and free-standing blood vessel analogues without ultraviolet illumination for high-volume vascularised tissue. Biofabrication. 2020;12(4):045033.  PubMed
Comments: I-AC fabricating/coating scaffold
Nie, Minghao; Nagata, Shogo; Aoyagi, Hoshimi; Itou, Akane; Shima, Ai; Takeuchi, Shoji. Cell-laden microfibers fabricated using μl cell-suspension. Biofabrication. 2020;12(4):045021.  PubMed
Comments: I-AC fabricating/coating scaffold
Shima, Ai; Itou, Akane; Takeuchi, Shoji. Cell fibers promote proliferation of co-cultured cells on a dish. Scientific Reports. 2020;10(1):288.  PubMed
Comments: I-AC fabricating/coating scaffold
Uzu, Miaki; Takezawa, Toshiaki. Novel microvascular endothelial model utilizing a collagen vitrigel membrane and its advantages for predicting histamine-induced microvascular hyperpermeability. Journal Of Pharmacological And Toxicological Methods. 2020;106( 32890732):106916.  PubMed
Comments: I-AC fabricating/coating scaffold
Watanabe, Takaichi; Okitsu, Teru; Ozawa, Fumisato; Nagata, Shogo; Matsunari, Hitomi; Nagashima, Hiroshi; Nagaya, Masaki; Teramae, Hiroki; Takeuchi, Shoji. Millimeter-thick xenoislet-laden fibers as retrievable transplants mitigate foreign body reactions for long-term glycemic control in diabetic mice. Biomaterials. 2020;255( 32562943):120162.  PubMed
Comments: I-AC fabricating/coating scaffold
Ikeda, Kazuhiro; Takeuchi, Shoji. Anchorage-dependent cell expansion in fiber-shaped microcarrier aggregates. Biotechnology Progress. 2019;35(2):e2755.  PubMed
Comments: I-AC fabricating/coating scaffold
Kurashina, Yuta; Sato, Ryo; Onoe, Hiroaki. Microfiber-shaped building-block tissues with endothelial networks for constructing macroscopic tissue assembly. Apl Bioengineering. 2019;3(4):046101.  PubMed
Comments: I-AC fabricating/coating scaffold