HLA-A*02:01 Mart-1 Tetramer-ELAGIGILTV-APC

MBL

Catalog No: MBL-TS-0009-2C

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The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.

Product Specifications

• Application: FC
• Reactivity: Human
• Conjugation: APC
• Peptide Sequence: ELAGIGILTV
• Class: Class I
• Sequence Location: 26-35
• MHC Allele: A*02:01

Citations for HLA-A*02:01 Mart-1 Tetramer-ELAGIGILTV-APC – 3 Found

Akiyama, Yasuto; Tanosaki, Ryuji; Inoue, Naoki; Shimada, Makiko; Hotate, Yukie; Yamamoto, Akifumi; Yamazaki, Naoya; Kawashima, Ichiro; Nukaya, Ikuei; Takesako, Kazutoh; Maruyama, Kouji; Takaue, Yoichi; Yamaguchi, Ken. Clinical response in Japanese metastatic melanoma patients treated with peptide cocktail-pulsed dendritic cells. Journal Of Translational Medicine. 2005;3(1):4. 

Takahara, Masashi; Miyai, Manami; Tomiyama, Mai; Mutou, Masato; Nicol, Andrew J; Nieda, Mie. Copulsing tumor antigen-pulsed dendritic cells with zoledronate efficiently enhance the expansion of tumor antigen-specific CD8+ T cells via Vgamma9gammadelta T cell activation. Journal Of Leukocyte Biology. 2008;83(3):742-54. 

Tomiyama, Mai; Takahara, Masashi; Egawa, Kohji; Nieda, Mie. Mature dendritic cells are superior to immature dendritic cells in expanding antigen-specific naive and memory CD8+ T cells. Anticancer Research. 2004;24(5C):3327-33.