Human Panc-1 Pancreatic Cancer Cells
Human Panc-1 Pancreatic Cancer Cells are a well-established human pancreatic cancer cell line derived from a pancreatic ductal adenocarcinoma (PDAC) isolated from a 56-year-old male donor [i]. Moreover, these cells exhibit an epithelial morphology and adhere to standard cell culture surfaces. Thus, Panc-1 cells are widely utilized in cancer research due to their metastatic potential and resistance to differentiation, making them a robust model for studying pancreatic cancer progression, therapeutic interventions, and drug resistance mechanisms.
Panc-1 cells play a crucial role in research on tumor migration, keratin reorganization, and cytoskeletal changes. Therefore, studies have highlighted their involvement in calcium-mediated actin resetting, a key process in cellular adaptation to physiological stress [ii]. Their ability to grow in both 2D and 3D culture systems makes them valuable for cancer research, high-throughput screening, and assay development. These cells naturally form clumps in culture, but trypsin treatment prevents aggregation [iii].
Human Panc-1 cells provide a reliable and well-characterized model for pancreatic cancer research, offering insights into tumor progression, metastasis, and therapeutic targeting. Their adaptability for both traditional and advanced culture techniques makes them a valuable asset for preclinical and translational research.
Product Specifications
- Source: Pancreatic ductal adenocarcinoma from a 56-year-old male donor
- Cell Type: Human pancreatic cancer epithelial cell line
- Morphology: Adherent, epithelial-like with a tendency to form clumps
- Applications:
- Pancreatic cancer research and metastasis studies
- Drug screening and resistance modeling
- 3D culture and tumor microenvironment studies
- High-throughput assay development
- Growth Characteristics: Metastatic potential with poor differentiation capacity
Related Products for Human Panc-1 Cells
- Human Panc-1 Expansion Media (CET-MR1012)
- Human Panc-1 Research Starter Kit (CET-BR1002)
Shipping & Storage
- Vial Size: Approximately 500,000 cells
- Shipping Conditions: Shipped on dry ice to maintain viability
- Storage Recommendation: Store in liquid nitrogen vapor phase for long-term preservation
Documents & Links for Human Panc-1 Cells | |
Datasheet | Human Panc-1 Cells Datasheet |
Vendor Page | Human Panc-1 Cells at Cellular Engineering Technologies |
Documents & Links for Human Panc-1 Cells | |
Datasheet | Human Panc-1 Cells Datasheet |
Vendor Page | Human Panc-1 Cells |