The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.
| Product Specifications | |
| Application | FC |
| Reactivity | Human |
| Conjugation | APC |
| Peptide Sequence | Tax 301-309 |
| Citations for HLA-A*24:02 HTLV-1 Tax 301-309 Tetramer-SFHSLHLLF-APC – 2 Found |
| Kozako, Tomohiro; Akimoto, Masaki; Toji, Shingo; White, Yohann; Suzuki, Susumu; Arima, Takehiro; Suruga, Yukio; Matsushita, Kakushi; Shimeno, Hiroshi; Soeda, Shinji; Kubota, Ryuji; Izumo, Shuji; Uozumi, Kimiharu; Arima, Naomichi. Target epitopes of HTLV-1 recognized by class I MHC-restricted cytotoxic T lymphocytes in patients with myelopathy and spastic paraparesis and infected patients with autoimmune disorders. Journal Of Medical Virology. 2011;83(3):501-9. PubMed |
| Jo, Tatsuro; Kaneko, Yohei; Oishi, Takayuki; Matsuzaka, Kaori; Shioya, Haruna; Sakai, Takahiro; Tomoinaga, Hiroo; Hayashi, Shizuka; Matsuo, Masatoshi; Taguchi, Jun. Elevation of Memory Cytotoxic T Lymphocytes, Including Human T Lymphotropic Virus Type 1 Tax-Specific and Hepatitis Virus Type C-Specific Cytotoxic T Lymphocytes, in a Patient with Adult T-Cell Leukemia/Lymphoma and Hepatocellular Carcinoma. Case Reports In Oncology. 2020;13(2):802-806. PubMed - Comments: Used in: FCM |