H-2Kb Negative Tetramer-SIYRYYGL-PE

MBL

Catalog No: MBL-TS-M008-1

Anti-mouse CD8 clone choice is critical when mouse MHC I tetramers, as some clones, including 53-6.7, lead to high background staining of all CD8+ T cells, rather than the antigen-specific ones. For best results, clone KT15, available from MBL International in FITC (K0227-4)is recommended. Additional information can be found in the datasheet that accompanies mouse class I tetramers, as well as the following reference containing a protocol for performing a cross titration series for optimization: Current Protocols in Immunology, MHC-Peptide tetramers to Visualize Antigen-Specific T Cells, Section 17.3.23-24, Supplement 146

Citations for H-2Kb Negative Tetramer-SIYRYYGL-PE – 5 Found

Wakita, Daiko; Chamoto, Kenji; Zhang, Yue; Narita, Yoshinori; Noguchi, Daisuke; Ohnishi, Hideaki; Iguchi, Takeshi; Sakai, Tomoaki; Ikeda, Hiroaki; Nishimura, Takashi. An indispensable role of type-1 IFNs for inducing CTL-mediated complete eradication of established tumor tissue by CpG-liposome co-encapsulated with model tumor antigen. International Immunology. 2006;18(3):425-34. 

Chamoto, Kenji; Wakita, Daiko; Narita, Yoshinori; Zhang, Yue; Noguchi, Daisuke; Ohnishi, Hideaki; Iguchi, Takeshi; Sakai, Tomoaki; Ikeda, Hiroaki; Nishimura, Takashi. An essential role of antigen-presenting cell/T-helper type 1 cell-cell interactions in draining lymph node during complete eradication of class II-negative tumor tissue by T-helper type 1 cell therapy. Cancer Research. 2006;66(3):1809-17. 

Asano, Jumpei; Tada, Hiroyuki; Onai, Nobuyuki; Sato, Taku; Horie, Yasuo; Fujimoto, Yukari; Fukase, Koichi; Suzuki, Akira; Mak, Tak W; Ohteki, Toshiaki. Nucleotide oligomerization binding domain-like receptor signaling enhances dendritic cell-mediated cross-priming in vivo. Journal Of Immunology (Baltimore, Md. : 1950). 2010;184(2):736-45. 

Du, Xuexiang; Tang, Fei; Liu, Mingyue; Su, Juanjuan; Zhang, Yan; Wu, Wei; Devenport, Martin; Lazarski, Christopher A; Zhang, Peng; Wang, Xu; Ye, Peiying; Wang, Changyu; Hwang, Eugene; Zhu, Tinghui; Xu, Ting; Zheng, Pan; Liu, Yang. A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy. Cell Research. 2018;28(4):416-432. 

Sivick, Kelsey E; Desbien, Anthony L; Glickman, Laura Hix; Reiner, Gabrielle L; Corrales, Leticia; Surh, Natalie H; Hudson, Thomas E; Vu, Uyen T; Francica, Brian J; Banda, Tamara; Katibah, George E; Kanne, David B; Leong, Justin J; Metchette, Ken; Bruml, Jacob R; Ndubaku, Chudi O; McKenna, Jeffrey M; Feng, Yan; Zheng, Lianxing; Bender, Steven L; Cho, Charles Y; Leong, Meredith L; van Elsas, Andrea; Dubensky, Thomas W Jr; McWhirter, Sarah M. Magnitude of Therapeutic STING Activation Determines CD8(+) T Cell-Mediated Anti-tumor Immunity. Cell Reports. 2018;25(11):3074-3085.e5.