This vector is designed for expression of MT-mKeima-Red (CoralHue TM Mitochondria-targeted monomeric Keima-Red) gene in mammalian cells. Keima-Red has been cloned from Monitpara sp. A monomeric version of CoralHue TM Keima-Red displays a bimodal excitation spectrum with peaks at 400 and 586nm in neutral and acidic solutions, respectively, and an emission maximum at 620 nm. Mitochondrial targeting of mKeima-Red is achieved by introducing a mitochondrial signal sequence at the N-terminus of mKeima-Red
| Citations for CoralHue Mitochondria-targeted monomeric Keima-Red (Hyg) – 2 Found |
| Safiulina, Dzhamilja; Kuum, Malle; Choubey, Vinay; Gogichaishvili, Nana; Liiv, Joanna; Hickey, Miriam A; Cagalinec, Michal; Mandel, Merle; Zeb, Akbar; Liiv, Mailis; Kaasik, Allen. Miro proteins prime mitochondria for Parkin translocation and mitophagy. The Embo Journal. 2019;38(2) PubMed |
| Puri, Rajat; Cheng, Xiu-Tang; Lin, Mei-Yao; Huang, Ning; Sheng, Zu-Hang. Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts. Nature Communications. 2019;10(1):3645. PubMed |