Collagen AGEs Assay Kit, CMA-Specific, Glyoxal
Cosmo Bio
- SKU:
- CSR-AAS-AGE-K03
- Shipping:
- Calculated at Checkout
$672.00
N epsilon-carboxymethylarginine (CMA), an AGE component was identified in glycated collagen (1), it generates during the reaction of collagen with reducing sugars or glyoxal. AGEs accumulation in collagen induced dermal fibroblasts to undergo apoptosis (2). Because AGEs accumulate in collagen as a function of aging (3), CMA may be involved in aging of collagen-rich tissues such as skin. CML is detected in many proteins such as collagen and albumin, whereas CMA is generates specifically in collagen, suggesting that CMA may provide a marker for collagen glycation. An anti-CMA monoclonal antibody specificallyand sensitively detects CMA in collagen (4).
CML ELISA Assay Kit provides rapid detection of CMA formed by glycation with glyoxal on the collagen
coating plate. This kit is suitable to the research for functional foods and cosmetic materialswhich have anti-glycation activity.
Principle: Collagen coated on 96-well plate is glycated by glyoxal and CMA is formed onto collagen coating wells for 7days at 37 °C. The inhibitory effects of glycation by aminoguanidin (positive control) or samples are probed with an anti-CMA antibody, followed by an HRP conjugated secondary antibody. The inhibitory effect of glycation in unknown sample is determined by comparing with the inhibitory effect of glycation by aminoguanidin (positivecontrol).
“Collagen AGEs Assay Kit, CMA-Specific, Glyoxal” is suitable to the research for functional foods and cosmetic materials which have an anti-glycation activity.
Documents & Links for Collagen AGEs Assay Kit, CMA-Specific, Glyoxal | |
Datasheet | csr-aas-age-k03e_collagen-ages-assay-kit-cma-specific-glyoxal_datasheet.pdf |
Flyer | csr-aas-age-k03e_collagen-ages-assay-kit-cma-specific-glyoxal_flyer.pdf |
Vendor Page | Collagen AGEs Assay Kit, CMA-Specific, Glyoxal at Cosmo Bio |
Documents & Links for Collagen AGEs Assay Kit, CMA-Specific, Glyoxal | |
Datasheet | csr-aas-age-k03e_collagen-ages-assay-kit-cma-specific-glyoxal_datasheet.pdf |
Flyer | csr-aas-age-k03e_collagen-ages-assay-kit-cma-specific-glyoxal_flyer.pdf |
Vendor Page | Collagen AGEs Assay Kit, CMA-Specific, Glyoxal |