Anti SWI/SNF-related Matrix-associated Actin-dependent Regulator of Chromatin Subfamily B Member 1 (SMARCB1/INI1/BAF47) mAb (Clone 2C2)

Cosmo Bio

SKU: CAC-CEC-037

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Background
SMARCB1/INI1/BAF47 is a core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal.

Application
Western blotting, 1/1,000 to 1/5,000
Immunocytochemistry, 1/500
Immunohistochemistry, 1/100 to 1/500

References
1) Hollmann and Hornick (2011) Am J Surg.

Product Specifications

• Application: ICC, IHC, WB, IF
• Reactivity: Mouse, Human
• Clonality: Monoclonal (Clone No.: 2C2)
• Host: Mouse