Anti-SOD1 (Human) mAb (Clone: 1G2)

MBL

Catalog No: MBL-M062-3

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Monoclonal Antibody of 100 μg targeting SOD1 for WB.

Product Specifications

• Application: WB
• Reactivity: Human
• Clonality: Monoclonal IgG1
• Host: Mouse
• Immunogen: Full-length recombinant human SOD1
• Gene ID - Human:

  6647

• Gene ID - Mouse:

  20655

• Formulation: This antibody is lyophilized form. Prepare a stock solution by dissolving the lyophilized antibody with 100 mL of distilled water. After reconstitution, IgG concentration should be 1 mg/mL in PBS (pH 7.2)/1% Sucrose. No preservative is contained.

Citations for Anti-SOD1 (Human) mAb (Clone: 1G2) – 11 Found

Hashimoto, Y; Niikura, T; Tajima, H; Yasukawa, T; Sudo, H; Ito, Y; Kita, Y; Kawasumi, M; Kouyama, K; Doyu, M; Sobue, G; Koide, T; Tsuji, S; Lang, J; Kurokawa, K; Nishimoto, I. A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2001;98(11):6336-41. 
- Comments: Used in: WB

Hashimoto, Yuichi; Tsuji, Osahiko; Kanekura, Kohsuke; Aiso, Sadakazu; Niikura, Takako; Matsuoka, Masaaki; Nishimoto, Ikuo. The Gtx homeodomain transcription factor exerts neuroprotection using its homeodomain. The Journal Of Biological Chemistry. 2004;279(16):16767-77. 
- Comments: Used in: WB

Kanekura, Kohsuke; Hashimoto, Yuichi; Niikura, Takako; Aiso, Sadakazu; Matsuoka, Masaaki; Nishimoto, Ikuo. Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants. The Journal Of Biological Chemistry. 2004;279(18):19247-56. 
- Comments: Used in: WB

Schonhoff, Christopher M; Matsuoka, Masaaki; Tummala, Hemachand; Johnson, Michael A; Estevéz, Alvaro G; Wu, Rui; Kamaid, Andrés; Ricart, Karina C; Hashimoto, Yuichi; Gaston, Benjamin; Macdonald, Timothy L; Xu, Zuoshang; Mannick, Joan B. S-nitrosothiol depletion in amyotrophic lateral sclerosis. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2006;103(7):2404-9. 
- Comments: Used in: WB

Nawa, Mikiro; Kanekura, Kohsuke; Hashimoto, Yuichi; Aiso, Sadakazu; Matsuoka, Masaaki. A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB. Cellular Signalling. 2008;20(3):493-505. 
- Comments: Used in: WB

Doi, Koji; Nakano, Toshiya; Kitayama, Michio; Watanabe, Yasuhiro; Yasui, Kenichi; Fukada, Yasuyo; Morino, Shinichi; Kaidoh, Toshiyuki; Nakashima, Kenji; Inoué, Takao. Mitochondrial changes in motor neurons of homozygotes of leucine 126 TT deletion SOD1 transgenic mice. Neuropathology : Official Journal Of The Japanese Society Of Neuropathology. 2008;28(3):269-76. 
- Comments: Used in: WB

Ren, Guijie; Ma, Zhongcai; Hui, Maria; Kudo, Lili C; Hui, Koon-Sea; Karsten, Stanislav L. Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis. Molecular Neurodegeneration. 2011;6:29. 
- Comments: Used in: WB

Hineno, Akiyo; Nakamura, Akinori; Shimojima, Yoshio; Yoshida, Kunihiro; Oyanagai, Kiyomitsu; Ikeda, Shu-ichi. Distinctive clinicopathological features of 2 large families with amyotrophic lateral sclerosis having L106V mutation in SOD1 gene. Journal Of The Neurological Sciences. 2012;319(1-2):63-74. 
- Comments: Used in: WB

Morisaki, Yuta; Niikura, Mamiko; Watanabe, Mizuho; Onishi, Kosuke; Tanabe, Shogo; Moriwaki, Yasuhiro; Okuda, Takashi; Ohara, Shinji; Murayama, Shigeo; Takao, Masaki; Uchida, Sae; Yamanaka, Koji; Misawa, Hidemi. Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9. Scientific Reports. 2016;6:27354. 
- Comments: Used in: IHC

Tokuda, Eiichi; Anzai, Itsuki; Nomura, Takao; Toichi, Keisuke; Watanabe, Masahiko; Ohara, Shinji; Watanabe, Seiji; Yamanaka, Koji; Morisaki, Yuta; Misawa, Hidemi; Furukawa, Yoshiaki. Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis. Molecular Neurodegeneration. 2017;12(1):2. 
- Comments: Used in: IHC

Komine, Okiru; Yamashita, Hirofumi; Fujimori-Tonou, Noriko; Koike, Masato; Jin, Shijie; Moriwaki, Yasuhiro; Endo, Fumito; Watanabe, Seiji; Uematsu, Satoshi; Akira, Shizuo; Uchiyama, Yasuo; Takahashi, Ryosuke; Misawa, Hidemi; Yamanaka, Koji. Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes. Cell Death And Differentiation. 2018;25(12):2130-2146. 
- Comments: Used in: IHC