Anti RBP-Jk mAb (Clone T6709)

Catalog No:
IIM-2ARBP2
$426.00
Application: ELISA, IHC, WB 
Clonality: Monoclonal 
Host: Rat 
Purification: Supernatant 
Reactivity: Mouse 
Citations for Anti RBP-Jk mAb (Clone T6709) – 8 Found
Intrahepatic bile duct regeneration in mice does not require Hnf6 or Notch signaling through Rbpj.
Am J Pathol. 2014 May;184(5):1479-88. doi: 10.1016/j.ajpath.2014.01.030. Epub 2014 Mar 13.  PubMed
The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.
Dev Biol. 2010 Jan 15;337(2):386-95. doi: 10.1016/j.ydbio.2009.11.017. Epub 2009 Nov 13.  PubMed
Epstein-Barr virus nuclear protein 3C domains necessary for lymphoblastoid cell growth: interaction with RBP-Jkappa regulates TCL1.
J Virol. 2009 Dec;83(23):12368-77. doi: 10.1128/JVI.01403-09. Epub 2009 Sep 23.  PubMed
Reduced Notch signaling leads to renal cysts and papillary microadenomas.
J Am Soc Nephrol. 2010 May;21(5):819-32. doi: 10.1681/ASN.2009090925. Epub 2010 Apr 8.  PubMed
Epstein-Barr virus nuclear protein 3C binds to the N-terminal (NTD) and beta trefoil domains (BTD) of RBP/CSL; only the NTD interaction is essential for lymphoblastoid cell growth.
Virology. 2011 May 25;414(1):19-25. doi: 10.1016/j.virol.2011.02.018. Epub 2011 Mar 26.  PubMed
Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response.
Sci Signal. 2015 Mar 24;8(369):ra30. doi: 10.1126/scisignal.2005892.  PubMed
Notch signaling is necessary to maintain quiescence in adult muscle stem cells.
Stem Cells. 2012 Feb;30(2):232-42. doi: 10.1002/stem.773.  PubMed
Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation.
J Immunol. 2009 Jun 15;182(12):7381-8. doi: 10.4049/jimmunol.0804322.  PubMed