Application: WB, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: preferentially expressed antigen in melanoma
Gene Name: PRAME
Alternative Gene Name: CT130, MAPE
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000028591: 55%, ENSRNOG00000037035: 55%
Entrez Gene ID: 23532
Uniprot ID: P78395
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: preferentially expressed antigen in melanoma
Gene Name: PRAME
Alternative Gene Name: CT130, MAPE
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000028591: 55%, ENSRNOG00000037035: 55%
Entrez Gene ID: 23532
Uniprot ID: P78395
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti PRAME pAb (ATL-HPA045153 w/enhanced validation) | |
| Antigen | PrEST Antigen PRAME (ATL-APrEST70289) |
| Documents & Links for Anti PRAME pAb (ATL-HPA045153 w/enhanced validation) | |
| Datasheet | Anti PRAME pAb (ATL-HPA045153 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti PRAME pAb (ATL-HPA045153 w/enhanced validation) at Atlas |
| Documents & Links for Anti PRAME pAb (ATL-HPA045153 w/enhanced validation) | |
| Datasheet | Anti PRAME pAb (ATL-HPA045153 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti PRAME pAb (ATL-HPA045153 w/enhanced validation) |
| Citations for Anti PRAME pAb (ATL-HPA045153 w/enhanced validation) – 5 Found |
| PRAME as an Independent Biomarker for Metastasis in Uveal Melanoma. Clin Cancer Res. 2016 Mar 1;22(5):1234-42. doi: 10.1158/1078-0432.CCR-15-2071. PubMed |
| PRAME expression and promoter hypomethylation in epithelial ovarian cancer. Oncotarget. 2016 Jul 19;7(29):45352-45369. doi: 10.18632/oncotarget.9977. PubMed |
| Impact of Preferentially Expressed Antigen of Melanoma on the Prognosis of Hepatocellular Carcinoma. Gastrointest Tumors. 2017 Mar;3(3-4):128-135. doi: 10.1159/000448137. Epub 2016 Aug 3. PubMed |
| A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens. J Clin Invest. 2017 Jun 30;127(7):2705-2718. doi: 10.1172/JCI92335. Epub 2017 Jun 19. PubMed |
| Preferentially expressed antigen in melanoma as a novel diagnostic marker differentiating thymic squamous cell carcinoma from thymoma. Sci Rep. 2020 Jul 23;10(1):12286. doi: 10.1038/s41598-020-69260-z. PubMed |