Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
| Product Specifications | |
| Application | WB, IHC, IP, ELISA |
| Reactivity | Human |
| Clonality | Monoclonal (Clone No.: 1.0E+9) |
| Documents & Links for Anti NFKBIA mAb (Clone 1E9) | |
| Datasheet | Anti NFKBIA mAb (Clone 1E9) Datasheet |
| Vendor Page | Anti NFKBIA mAb (Clone 1E9) at CUSABIO |
| Documents & Links for Anti NFKBIA mAb (Clone 1E9) | |
| Datasheet | Anti NFKBIA mAb (Clone 1E9) Datasheet |
| Vendor Page | Anti NFKBIA mAb (Clone 1E9) |