Anti MPST pAb (ATL-HPA001240 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA001240-100
  • Immunohistochemical staining of human liver shows strong granular cytoplasmic positivity in hepatocytes.
  • Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.
  • Western blot analysis in human cell lines HEK293 and U-251MG using Anti-MPST antibody. Corresponding MPST RNA-seq data are presented for the same cell lines. Loading control: Anti-PFN1.
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Protein Description: mercaptopyruvate sulfurtransferase
Gene Name: MPST
Alternative Gene Name: MST, TST2
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000071711: 81%, ENSRNOG00000000185: 82%
Entrez Gene ID: 4357
Uniprot ID: P25325
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen AVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPD
Gene Sequence AVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCGSGVTACHVALGAYLCGKPD
Gene ID - Mouse ENSMUSG00000071711
Gene ID - Rat ENSRNOG00000000185
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti MPST pAb (ATL-HPA001240 w/enhanced validation)
Datasheet Anti MPST pAb (ATL-HPA001240 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti MPST pAb (ATL-HPA001240 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti MPST pAb (ATL-HPA001240 w/enhanced validation)
Datasheet Anti MPST pAb (ATL-HPA001240 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti MPST pAb (ATL-HPA001240 w/enhanced validation)



Citations for Anti MPST pAb (ATL-HPA001240 w/enhanced validation) – 18 Found
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Ahmad, Akbar; Gerö, Domokos; Olah, Gabor; Szabo, Csaba. Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase. International Journal Of Molecular Medicine. 2016;38(6):1683-1692.  PubMed
Hine, Christopher; Kim, Hyo-Jeong; Zhu, Yan; Harputlugil, Eylul; Longchamp, Alban; Matos, Marina Souza; Ramadoss, Preeti; Bauerle, Kevin; Brace, Lear; Asara, John M; Ozaki, C Keith; Cheng, Sheue-Yann; Singha, Subhankar; Ahn, Kyo Han; Kimmelman, Alec; Fisher, Ffolliott M; Pissios, Pavlos; Withers, Dominic J; Selman, Colin; Wang, Rui; Yen, Kelvin; Longo, Valter D; Cohen, Pinchas; Bartke, Andrzej; Kopchick, John J; Miller, Richard; Hollenberg, Anthony N; Mitchell, James R. Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production. Cell Metabolism. 2017;25(6):1320-1333.e5.  PubMed
Abdollahi Govar, Armita; Törő, Gábor; Szaniszlo, Peter; Pavlidou, Athanasia; Bibli, Sofia-Iris; Thanki, Ketan; Resto, Vicente A; Chao, Celia; Hellmich, Mark R; Szabo, Csaba; Papapetropoulos, Andreas; Módis, Katalin. 3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics. British Journal Of Pharmacology. 2020;177(4):866-883.  PubMed
Yuan, Chao; Hou, Hai-Tao; Chen, Huan-Xin; Wang, Jun; Wang, Zheng-Qing; Chen, Tie-Nan; Novakovic, Aleksandra; Marinko, Marija; Yang, Qin; Liu, Zhi-Gang; He, Guo-Wei. Hydrogen sulfide-mediated endothelial function and the interaction with eNOS and PDE5A activity in human internal mammary arteries. The Journal Of International Medical Research. 2019;47(8):3778-3791.  PubMed
Morales-Loredo, Humberto; Barrera, Adelaeda; Garcia, Joshua M; Pace, Carolyn E; Naik, Jay S; Gonzalez Bosc, Laura V; Kanagy, Nancy L. Hydrogen sulfide regulation of renal and mesenteric blood flow. American Journal Of Physiology. Heart And Circulatory Physiology. 2019;317(5):H1157-H1165.  PubMed
Katsouda, Antonia; Peleli, Maria; Asimakopoulou, Antonia; Papapetropoulos, Andreas; Beis, Dimitris. Generation and Characterization of a CRISPR/Cas9 -Induced 3-mst Deficient Zebrafish. Biomolecules. 2020;10(2)  PubMed
González-García, Pilar; Hidalgo-Gutiérrez, Agustín; Mascaraque, Cristina; Barriocanal-Casado, Eliana; Bakkali, Mohammed; Ziosi, Marcello; Abdihankyzy, Ussipbek Botagoz; Sánchez-Hernández, Sabina; Escames, Germaine; Prokisch, Holger; Martín, Francisco; Quinzii, Catarina M; López, Luis C. Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism. Human Molecular Genetics. 2020;29(19):3296-3311.  PubMed
Trautwein, Britta; Merz, Tamara; Denoix, Nicole; Szabo, Csaba; Calzia, Enrico; Radermacher, Peter; McCook, Oscar. ΔMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage. Antioxidants (Basel, Switzerland). 2021;10(2)  PubMed
Katsouda, Antonia; Valakos, Dimitrios; Dionellis, Vasilios S; Bibli, Sofia-Iris; Akoumianakis, Ioannis; Karaliota, Sevasti; Zuhra, Karim; Fleming, Ingrid; Nagahara, Noriyuki; Havaki, Sophia; Gorgoulis, Vassilis G; Thanos, Dimitris; Antoniades, Charalambos; Szabo, Csaba; Papapetropoulos, Andreas. MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity. The Journal Of Experimental Medicine. 2022;219(7)  PubMed
Jiang, Xiaofeng; MacArthur, Michael R; Treviño-Villarreal, J Humberto; Kip, Peter; Ozaki, C Keith; Mitchell, Sarah J; Mitchell, James R. Intracellular H(2)S production is an autophagy-dependent adaptive response to DNA damage. Cell Chemical Biology. 2021;28(12):1669-1678.e5.  PubMed
Zivanovic, Jasmina; Kouroussis, Emilia; Kohl, Joshua B; Adhikari, Bikash; Bursac, Biljana; Schott-Roux, Sonia; Petrovic, Dunja; Miljkovic, Jan Lj; Thomas-Lopez, Daniel; Jung, Youngeun; Miler, Marko; Mitchell, Sarah; Milosevic, Verica; Gomes, Jose Eduardo; Benhar, Moran; Gonzalez-Zorn, Bruno; Ivanovic-Burmazovic, Ivana; Torregrossa, Roberta; Mitchell, James R; Whiteman, Matthew; Schwarz, Guenter; Snyder, Solomon H; Paul, Bindu D; Carroll, Kate S; Filipovic, Milos R. Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration. Cell Metabolism. 2019;30(6):1152-1170.e13.  PubMed
Katsouda, Antonia; Markou, Maria; Zampas, Paraskevas; Varela, Aimilia; Davos, Constantinos H; Vellecco, Valentina; Cirino, Giuseppe; Bucci, Mariarosaria; Papapetropoulos, Andreas. CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway. Frontiers In Pharmacology. 14( 36860295):1090654.  PubMed