Application: IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: mitochondrial calcium uniporter dominant negative beta subunit
Gene Name: MCUB
Alternative Gene Name: CCDC109B, FLJ20647
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000027994: 75%, ENSRNOG00000009433: 74%
Entrez Gene ID: 55013
Uniprot ID: Q9NWR8
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: mitochondrial calcium uniporter dominant negative beta subunit
Gene Name: MCUB
Alternative Gene Name: CCDC109B, FLJ20647
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000027994: 75%, ENSRNOG00000009433: 74%
Entrez Gene ID: 55013
Uniprot ID: Q9NWR8
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti MCUB pAb (ATL-HPA048776 w/enhanced validation) | |
| Antigen | PrEST Antigen MCUB (ATL-APrEST85246) |
| Documents & Links for Anti MCUB pAb (ATL-HPA048776 w/enhanced validation) | |
| Datasheet | Anti MCUB pAb (ATL-HPA048776 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti MCUB pAb (ATL-HPA048776 w/enhanced validation) at Atlas |
| Documents & Links for Anti MCUB pAb (ATL-HPA048776 w/enhanced validation) | |
| Datasheet | Anti MCUB pAb (ATL-HPA048776 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti MCUB pAb (ATL-HPA048776 w/enhanced validation) |
| Citations for Anti MCUB pAb (ATL-HPA048776 w/enhanced validation) – 3 Found |
| Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function. J Biol Chem. 2018 May 25;293(21):8182-8195. doi: 10.1074/jbc.RA118.002066. Epub 2018 Apr 6. PubMed |
| Mild Traumatic Brain Injury Induces Mitochondrial Calcium Overload and Triggers the Upregulation of NCLX in the Hippocampus. Antioxidants (Basel). 2023 Feb 7;12(2):403. doi: 10.3390/antiox12020403. PubMed |
| MCU Upregulation Overactivates Mitophagy by Promoting VDAC1 Dimerization and Ubiquitination in the Hepatotoxicity of Cadmium. Adv Sci (Weinh). 2023 Mar;10(7):e2203869. doi: 10.1002/advs.202203869. Epub 2023 Jan 15. PubMed |