IHC image of CSB-RA013003A0HU diluted at 1:115 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Anti LMNA mAb (Clone 4H7)

Catalog No:
CSB-RA013003A0HU-50
$210.00

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Application: IHC, IF, IP, FC, ELISA 
Clonality: Monoclonal 
Purification: Purified - Affinity 
Reactivity: Human 
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation (PubMed:10080180, PubMed:22431096, PubMed:10814726, PubMed:11799477, PubMed:18551513). Required for osteoblastogenesis and bone formation (PubMed:12075506, PubMed:15317753, PubMed:18611980). Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone (PubMed:10587585). Required for cardiac homeostasis (PubMed:10580070, PubMed:12927431, PubMed:18611980, PubMed:23666920).
Documents & Links for Anti LMNA mAb (Clone 4H7)
Datasheet Anti LMNA mAb (Clone 4H7) Datasheet
Vendor Page Anti LMNA mAb (Clone 4H7) at CUSABIO

Documents & Links for Anti LMNA mAb (Clone 4H7)
Datasheet Anti LMNA mAb (Clone 4H7) Datasheet
Vendor Page Anti LMNA mAb (Clone 4H7)