Product Specifications | |
Application | FC, ICC, IP, WB, IHC |
Reactivity | Human, Mouse, Rat, Hamster, Zebrafish |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Recombinant human LC3 (MAP1LC3B :1-120 a.a.) |
Formulation | PBS/50% glycerol, pH 7.2 |
Storage |
Documents & Links for Anti-LC3 pAb | |
Datasheet | Anti-LC3 pAb Datasheet |
Documents & Links for Anti-LC3 pAb | |
Datasheet | Anti-LC3 pAb Datasheet |
Citations for Anti-LC3 pAb – 152 Found |
Saitoh, Tatsuya; Fujita, Naonobu; Jang, Myoung Ho; Uematsu, Satoshi; Yang, Bo-Gie; Satoh, Takashi; Omori, Hiroko; Noda, Takeshi; Yamamoto, Naoki; Komatsu, Masaaki; Tanaka, Keiji; Kawai, Taro; Tsujimura, Tohru; Takeuchi, Osamu; Yoshimori, Tamotsu; Akira, Shizuo. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature. 2008;456(7219):264-8. PubMed - Comments: Used in: WB |
Katona, Istvan; Zhang, Xuebao; Bai, Yunhong; Shy, Michael E; Guo, Jiasong; Yan, Qing; Hatfield, James; Kupsky, William J; Li, Jun. Distinct pathogenic processes between Fig4-deficient motor and sensory neurons. The European Journal Of Neuroscience. 2011;33(8):1401-10. PubMed - Comments: Used in: WB |
Wu, Ya-Na; Yang, Li-Xing; Shi, Xuan-Yu; Li, I-Chen; Biazik, Joanna M; Ratinac, Kyle R; Chen, Dong-Hwang; Thordarson, Pall; Shieh, Dar-Bin; Braet, Filip. The selective growth inhibition of oral cancer by iron core-gold shell nanoparticles through mitochondria-mediated autophagy. Biomaterials. 2011;32(20):4565-73. PubMed - Comments: Used in: ICC |
Lee, Eun-Ju; Tournier, Cathy. The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy. Autophagy. 2011;7(7):689-95. PubMed - Comments: Used in: WB |
Pan, Ji-An; Ullman, Erica; Dou, Zhixun; Zong, Wei-Xing. Inhibition of protein degradation induces apoptosis through a microtubule-associated protein 1 light chain 3-mediated activation of caspase-8 at intracellular membranes. Molecular And Cellular Biology. 2011;31(15):3158-70. PubMed - Comments: Used in: WB |
Huang, Ying; Hou, Jia-Kai; Chen, Ting-Ting; Zhao, Xu-Yun; Yan, Zhao-Wen; Zhang, Jing; Yang, Jie; Kogan, Scott C; Chen, Guo-Qiang. PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway. Autophagy. 2011;7(10):1132-44. PubMed - Comments: Used in: WB |
Hasui, Kazuhisa; Wang, Jia; Jia, Xinshan; Tanaka, Masashi; Nagai, Taku; Matsuyama, Takami; Eizuru, Yoshito. Enhanced Autophagy and Reduced Expression of Cathepsin D Are Related to Autophagic Cell Death in Epstein-Barr Virus-Associated Nasal Natural Killer/T-Cell Lymphomas: An Immunohistochemical Analysis of Beclin-1, LC3, Mitochondria (AE-1), and Cathepsin D in Nasopharyngeal Lymphomas. Acta Histochemica Et Cytochemica. 2011;44(3):119-31. PubMed - Comments: Used in: IHC |
Miranda, Soledad; González-Rodríguez, Águeda; García-Ramírez, Marta; Revuelta-Cervantes, Jesús; Hernández, Cristina; Simó, Rafael; Valverde, Ángela M. Beneficial effects of fenofibrate in retinal pigment epithelium by the modulation of stress and survival signaling under diabetic conditions. Journal Of Cellular Physiology. 2012;227(6):2352-62. PubMed - Comments: Used in: WB |
Otomo, Takanobu; Higaki, Katsumi; Nanba, Eiji; Ozono, Keiichi; Sakai, Norio. Lysosomal storage causes cellular dysfunction in mucolipidosis II skin fibroblasts. The Journal Of Biological Chemistry. 2011;286(40):35283-90. PubMed - Comments: Used in: WB |
Yan, Jun; Li, Qing-Fang; Wang, Li-Sheng; Wang, Hua; Xiao, Feng-Jun; Yang, Yue-Feng; Wu, Chu-Tse. Methyl-β-cyclodextrin induces programmed cell death in chronic myeloid leukemia cells and, combined with imatinib, produces a synergistic downregulation of ERK/SPK1 signaling. Anti-Cancer Drugs. 2012;23(1):22-31. PubMed - Comments: Used in: WB |
Yan, Jun; Li, Qing-Fang; Wang, Li-Sheng; Wang, Hua; Xiao, Feng-Jun; Yang, Yue-Feng; Wu, Chu-Tse. Methyl-β-cyclodextrin induces programmed cell death in chronic myeloid leukemia cells and, combined with imatinib, produces a synergistic downregulation of ERK/SPK1 signaling. Anti-Cancer Drugs. 2012;23(1):22-31. PubMed - Comments: Used in: ICC |
Takaesu, Giichi; Kobayashi, Takashi; Yoshimura, Akihiko. TGFβ-activated kinase 1 (TAK1)-binding proteins (TAB) 2 and 3 negatively regulate autophagy. Journal Of Biochemistry. 2012;151(2):157-66. PubMed - Comments: Used in: WB |
Taguwa, Shuhei; Kambara, Hiroto; Fujita, Naonobu; Noda, Takeshi; Yoshimori, Tamotsu; Koike, Kazuhiko; Moriishi, Kohji; Matsuura, Yoshiharu. Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus. Journal Of Virology. 2011;85(24):13185-94. PubMed - Comments: Used in: WB |
Taguwa, Shuhei; Kambara, Hiroto; Fujita, Naonobu; Noda, Takeshi; Yoshimori, Tamotsu; Koike, Kazuhiko; Moriishi, Kohji; Matsuura, Yoshiharu. Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus. Journal Of Virology. 2011;85(24):13185-94. PubMed - Comments: Used in: ICC |
Xu, Teng; Su, Hang; Ganapathy, Suthakar; Yuan, Zhi-Min. Modulation of autophagic activity by extracellular pH. Autophagy. 2011;7(11):1316-22. PubMed - Comments: Used in: WB |
Rasmussen, Simon B; Horan, Kristy A; Holm, Christian K; Stranks, Amanda J; Mettenleiter, Thomas C; Simon, A Katharina; Jensen, Søren B; Rixon, Frazer J; He, Bin; Paludan, Søren R. Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes. Journal Of Immunology (Baltimore, Md. : 1950). 2011;187(10):5268-76. PubMed - Comments: Used in: WB |
Rasmussen, Simon B; Horan, Kristy A; Holm, Christian K; Stranks, Amanda J; Mettenleiter, Thomas C; Simon, A Katharina; Jensen, Søren B; Rixon, Frazer J; He, Bin; Paludan, Søren R. Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes. Journal Of Immunology (Baltimore, Md. : 1950). 2011;187(10):5268-76. PubMed - Comments: Used in: ICC |
Wu, Shan-Ying; Lan, Sheng-Hui; Cheng, Da-En; Chen, Wei-Kai; Shen, Cheng-Huang; Lee, Ying-Ray; Zuchini, Roberto; Liu, Hsiao-Sheng. Ras-related tumorigenesis is suppressed by BNIP3-mediated autophagy through inhibition of cell proliferation. Neoplasia (New York, N.y.). 2011;13(12):1171-82. PubMed - Comments: Used in: WB |
Starr, Tregei; Child, Robert; Wehrly, Tara D; Hansen, Bryan; Hwang, Seungmin; López-Otin, Carlos; Virgin, Herbert W; Celli, Jean. Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle. Cell Host & Microbe. 2012;11(1):33-45. PubMed - Comments: Used in: WB |
Starr, Tregei; Child, Robert; Wehrly, Tara D; Hansen, Bryan; Hwang, Seungmin; López-Otin, Carlos; Virgin, Herbert W; Celli, Jean. Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle. Cell Host & Microbe. 2012;11(1):33-45. PubMed - Comments: Used in: ICC |
Kaini, Ramesh R; Sillerud, Laurel O; Zhaorigetu, Siqin; Hu, Chien-An A. Autophagy regulates lipolysis and cell survival through lipid droplet degradation in androgen-sensitive prostate cancer cells. The Prostate. 2012;72(13):1412-22. PubMed - Comments: Used in: WB |
Yu, Xin; Ajayi, Abiodun; Boga, Narasimha Rao; Ström, Anna-Lena. Differential degradation of full-length and cleaved ataxin-7 fragments in a novel stable inducible SCA7 model. Journal Of Molecular Neuroscience : Mn. 2012;47(2):219-33. PubMed - Comments: Used in: WB |
Niizuma, Shinichiro; Inuzuka, Yasutaka; Okuda, Junji; Kato, Takao; Kawashima, Tsuneaki; Tamaki, Yodo; Iwanaga, Yoshitaka; Yoshida, Yuki; Kosugi, Rie; Watanabe-Maeda, Kayo; Machida, Yoji; Tsuji, Shingo; Aburatani, Hiroyuki; Izumi, Tohru; Kita, Toru; Kimura, Takeshi; Shioi, Tetsuo. Effect of persistent activation of phosphoinositide 3-kinase on heart. Life Sciences. 2012;90(15-16):619-28. PubMed - Comments: Used in: WB |
Seillier, M; Peuget, S; Gayet, O; Gauthier, C; N'Guessan, P; Monte, M; Carrier, A; Iovanna, J L; Dusetti, N J. TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death. Cell Death And Differentiation. 2012;19(9):1525-35. PubMed - Comments: Used in: ICC |
Kaminskyy, Vitaliy O; Piskunova, Tatiana; Zborovskaya, Irina B; Tchevkina, Elena M; Zhivotovsky, Boris. Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation. Autophagy. 2012;8(7):1032-44. PubMed - Comments: Used in: WB |
Kaminskyy, Vitaliy O; Piskunova, Tatiana; Zborovskaya, Irina B; Tchevkina, Elena M; Zhivotovsky, Boris. Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation. Autophagy. 2012;8(7):1032-44. PubMed - Comments: Used in: ICC |
Botbol, Yair; Patel, Bindi; Macian, Fernando. Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation. Autophagy. 11(10):1864-77. PubMed - Comments: Used in: WB |
Botbol, Yair; Patel, Bindi; Macian, Fernando. Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation. Autophagy. 11(10):1864-77. PubMed - Comments: Used in: IP |
Botbol, Yair; Patel, Bindi; Macian, Fernando. Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation. Autophagy. 11(10):1864-77. PubMed - Comments: Used in: ICC |
Botbol, Yair; Macian, Fernando. Assays for Monitoring Macroautophagy Activity in T cells. Methods In Molecular Biology (Clifton, N.j.). 1343:143-53. PubMed - Comments: Used in: WB |
Botbol, Yair; Macian, Fernando. Assays for Monitoring Macroautophagy Activity in T cells. Methods In Molecular Biology (Clifton, N.j.). 1343:143-53. PubMed - Comments: Used in: ICC |
Cherepkova, M Y; Sineva, G S; Pospelov, V A. Leukemia inhibitory factor (LIF) withdrawal activates mTOR signaling pathway in mouse embryonic stem cells through the MEK/ERK/TSC2 pathway. Cell Death & Disease. 2016;7(1):e2050. PubMed - Comments: Used in: ICC |
Guo, Jing L; Buist, Arjan; Soares, Alberto; Callaerts, Kathleen; Calafate, Sara; Stevenaert, Frederik; Daniels, Joshua P; Zoll, Bryan E; Crowe, Alex; Brunden, Kurt R; Moechars, Diederik; Lee, Virginia M Y. The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES. The Journal Of Biological Chemistry. 2016;291(25):13175-93. PubMed - Comments: Used in: WB |
Guo, Jing L; Buist, Arjan; Soares, Alberto; Callaerts, Kathleen; Calafate, Sara; Stevenaert, Frederik; Daniels, Joshua P; Zoll, Bryan E; Crowe, Alex; Brunden, Kurt R; Moechars, Diederik; Lee, Virginia M Y. The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES. The Journal Of Biological Chemistry. 2016;291(25):13175-93. PubMed - Comments: Used in: ICC |
Sano, Osamu; Kazetani, Kenichi; Funata, Masaaki; Fukuda, Yasunori; Matsui, Junji; Iwata, Hidehisa. Vacuolin-1 inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition. Febs Letters. 2016;590(11):1576-85. PubMed - Comments: Used in: WB |
Fujita, Naonobu; Huang, Wilson; Lin, Tzu-Han; Groulx, Jean-Francois; Jean, Steve; Nguyen, Jen; Kuchitsu, Yoshihiko; Koyama-Honda, Ikuko; Mizushima, Noboru; Fukuda, Mitsunori; Kiger, Amy A. Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. Elife. 2017;6 PubMed |
Fujita, Naonobu; Huang, Wilson; Lin, Tzu-Han; Groulx, Jean-Francois; Jean, Steve; Nguyen, Jen; Kuchitsu, Yoshihiko; Koyama-Honda, Ikuko; Mizushima, Noboru; Fukuda, Mitsunori; Kiger, Amy A. Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. Elife. 2017;6 PubMed - Comments: Used in: WB |
Fujita, Naonobu; Huang, Wilson; Lin, Tzu-Han; Groulx, Jean-Francois; Jean, Steve; Nguyen, Jen; Kuchitsu, Yoshihiko; Koyama-Honda, Ikuko; Mizushima, Noboru; Fukuda, Mitsunori; Kiger, Amy A. Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. Elife. 2017;6 PubMed - Comments: Used in: ICC |
Girault, Virginie; Gilard, Vianney; Marguet, Florent; Lesueur, Céline; Hauchecorne, Michelle; Ramdani, Yasmina; Laquerrière, Annie; Marret, Stéphane; Jégou, Sylvie; Gonzalez, Bruno Jose; Brasse-Lagnel, Carole; Bekri, Soumeya. Prenatal alcohol exposure impairs autophagy in neonatal brain cortical microvessels. Cell Death & Disease. 2017;8(2):e2610. PubMed - Comments: Used in: ICC |
Girault, Virginie; Gilard, Vianney; Marguet, Florent; Lesueur, Céline; Hauchecorne, Michelle; Ramdani, Yasmina; Laquerrière, Annie; Marret, Stéphane; Jégou, Sylvie; Gonzalez, Bruno Jose; Brasse-Lagnel, Carole; Bekri, Soumeya. Prenatal alcohol exposure impairs autophagy in neonatal brain cortical microvessels. Cell Death & Disease. 2017;8(2):e2610. PubMed - Comments: Used in: IHC |
Cao, Mian; Wu, Yumei; Ashrafi, Ghazaleh; McCartney, Amber J; Wheeler, Heather; Bushong, Eric A; Boassa, Daniela; Ellisman, Mark H; Ryan, Timothy A; De Camilli, Pietro. Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons. Neuron. 2017;93(4):882-896.e5. PubMed - Comments: Used in: WB |
Taguchi, Yuki; Horiuchi, Yuta; Kano, Fumi; Murata, Masayuki. Novel prosurvival function of Yip1A in human cervical cancer cells: constitutive activation of the IRE1 and PERK pathways of the unfolded protein response. Cell Death & Disease. 2017;8(3):e2718. PubMed - Comments: Used in: WB |
Chen, Liqun; Wang, Ke; Long, Aijun; Jia, Liangjie; Zhang, Yuanyuan; Deng, Haiteng; Li, Yu; Han, Jinbo; Wang, Yiguo. Fasting-induced hormonal regulation of lysosomal function. Cell Research. 2017;27(6):748-763. PubMed - Comments: Used in: WB |
Sakamoto, Shuichiro; Miyara, Masatsugu; Sanoh, Seigo; Ohta, Shigeru; Kotake, Yaichiro. Mild MPP(+) exposure-induced glucose starvation enhances autophagosome synthesis and impairs its degradation. Scientific Reports. 2017;7:46668. PubMed - Comments: Used in: WB |
Arasaki, Kohei; Mikami, Yumi; Shames, Stephanie R; Inoue, Hiroki; Wakana, Yuichi; Tagaya, Mitsuo. Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17. Nature Communications. 2017;8:15406. PubMed - Comments: Used in: WB |
Takahashi, Kenichi; Mashima, Hirosato; Miura, Kouichi; Maeda, Daichi; Goto, Akiteru; Goto, Takashi; Sun-Wada, Ge-Hong; Wada, Yoh; Ohnishi, Hirohide. Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models. Scientific Reports. 2017;7(1):2817. PubMed - Comments: Used in: WB |
Kim, Tae Sung; Shin, Yern-Hyerk; Lee, Hye-Mi; Kim, Jin Kyung; Choe, Jin Ho; Jang, Ji-Chan; Um, Soohyun; Jin, Hyo Sun; Komatsu, Masaaki; Cha, Guang-Ho; Chae, Han-Jung; Oh, Dong-Chan; Jo, Eun-Kyeong. Ohmyungsamycins promote antimicrobial responses through autophagy activation via AMP-activated protein kinase pathway. Scientific Reports. 2017;7(1):3431. PubMed - Comments: Used in: ICC |
Hori, Ikumi; Otomo, Takanobu; Nakashima, Mitsuko; Miya, Fuyuki; Negishi, Yutaka; Shiraishi, Hideaki; Nonoda, Yutaka; Magara, Shinichi; Tohyama, Jun; Okamoto, Nobuhiko; Kumagai, Takeshi; Shimoda, Konomi; Yukitake, Yoshiya; Kajikawa, Daigo; Morio, Tomohiro; Hattori, Ayako; Nakagawa, Motoo; Ando, Naoki; Nishino, Ichizo; Kato, Mitsuhiro; Tsunoda, Tatsuhiko; Saitsu, Hirotomo; Kanemura, Yonehiro; Yamasaki, Mami; Kosaki, Kenjiro; Matsumoto, Naomichi; Yoshimori, Tamotsu; Saitoh, Shinji. Defects in autophagosome-lysosome fusion underlie Vici syndrome, a neurodevelopmental disorder with multisystem involvement. Scientific Reports. 2017;7(1):3552. PubMed - Comments: Used in: WB |
Hori, Ikumi; Otomo, Takanobu; Nakashima, Mitsuko; Miya, Fuyuki; Negishi, Yutaka; Shiraishi, Hideaki; Nonoda, Yutaka; Magara, Shinichi; Tohyama, Jun; Okamoto, Nobuhiko; Kumagai, Takeshi; Shimoda, Konomi; Yukitake, Yoshiya; Kajikawa, Daigo; Morio, Tomohiro; Hattori, Ayako; Nakagawa, Motoo; Ando, Naoki; Nishino, Ichizo; Kato, Mitsuhiro; Tsunoda, Tatsuhiko; Saitsu, Hirotomo; Kanemura, Yonehiro; Yamasaki, Mami; Kosaki, Kenjiro; Matsumoto, Naomichi; Yoshimori, Tamotsu; Saitoh, Shinji. Defects in autophagosome-lysosome fusion underlie Vici syndrome, a neurodevelopmental disorder with multisystem involvement. Scientific Reports. 2017;7(1):3552. PubMed - Comments: Used in: ICC |
Lu, Shiou-Ling; Kawabata, Tsuyoshi; Cheng, Yi-Lin; Omori, Hiroko; Hamasaki, Maho; Kusaba, Tatsuya; Iwamoto, Ryo; Arimoto, Hirokazu; Noda, Takeshi; Lin, Yee-Shin; Yoshimori, Tamotsu. Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes. Plos Pathogens. 2017;13(7):e1006444. PubMed - Comments: Used in: WB |
Lu, Shiou-Ling; Kawabata, Tsuyoshi; Cheng, Yi-Lin; Omori, Hiroko; Hamasaki, Maho; Kusaba, Tatsuya; Iwamoto, Ryo; Arimoto, Hirokazu; Noda, Takeshi; Lin, Yee-Shin; Yoshimori, Tamotsu. Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes. Plos Pathogens. 2017;13(7):e1006444. PubMed - Comments: Used in: ICC |
Ono, Akito; Sano, Osamu; Kazetani, Ken-Ichi; Muraki, Takamichi; Imamura, Keisuke; Sumi, Hiroyuki; Matsui, Junji; Iwata, Hidehisa. Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition. Plos One. 12(7):e0181243. PubMed - Comments: Used in: WB |
Ono, Akito; Sano, Osamu; Kazetani, Ken-Ichi; Muraki, Takamichi; Imamura, Keisuke; Sumi, Hiroyuki; Matsui, Junji; Iwata, Hidehisa. Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition. Plos One. 12(7):e0181243. PubMed - Comments: Used in: ICC |
Chen, Ying-Da; Fang, Yi-Ting; Cheng, Yi-Lin; Lin, Chiou-Feng; Hsu, Li-Jin; Wang, Shu-Ying; Anderson, Robert; Chang, Chih-Peng; Lin, Yee-Shin. Exophagy of annexin A2 via RAB11, RAB8A and RAB27A in IFN-γ-stimulated lung epithelial cells. Scientific Reports. 2017;7(1):5676. PubMed - Comments: Used in: ICC |
Cheng, Yi-Lin; Wu, Yan-Wei; Kuo, Chih-Feng; Lu, Shiou-Ling; Liu, Fu-Tong; Anderson, Robert; Lin, Chiou-Feng; Liu, Yi-Ling; Wang, Wan-Yu; Chen, Ying-Da; Zheng, Po-Xing; Wu, Jiunn-Jong; Lin, Yee-Shin. Galectin-3 Inhibits Galectin-8/Parkin-Mediated Ubiquitination of Group A Streptococcus. Mbio. 2017;8(4) PubMed - Comments: Used in: ICC |
Kjos, Ingrid; Borg Distefano, Marita; Sætre, Frank; Repnik, Urska; Holland, Petter; Jones, Arwyn T; Engedal, Nikolai; Simonsen, Anne; Bakke, Oddmund; Progida, Cinzia. Rab7b modulates autophagic flux by interacting with Atg4B. Embo Reports. 2017;18(10):1727-1739. PubMed - Comments: Used in: ICC |
Anzai, Erina; Hirata, Kensuke; Shibazaki, Misato; Yamada, Chiaki; Morii, Mariko; Honda, Takuya; Yamaguchi, Naoto; Yamaguchi, Noritaka. FOXA1 Induces E-Cadherin Expression at the Protein Level via Suppression of Slug in Epithelial Breast Cancer Cells. Biological & Pharmaceutical Bulletin. 40(9):1483-1489. PubMed - Comments: Used in: WB |
Zhao, Qiong; Hu, Zhan-Ying; Zhang, Jing-Pu; Jiang, Jian-Dong; Ma, Yuan-Yuan; Li, Jian-Rui; Peng, Zong-Gen; Chen, Jin-Hua. Dual Roles of Two Isoforms of Autophagy-related Gene ATG10 in HCV-Subgenomic replicon Mediated Autophagy Flux and Innate Immunity. Scientific Reports. 2017;7(1):11250. PubMed - Comments: Used in: WB |
Meng, Xiang-Hui; Chen, Bo; Zhang, Jing-Pu. Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes. International Journal Of Biological Sciences. 13(8):985-995. PubMed - Comments: Used in: WB |
Meng, Xiang-Hui; Chen, Bo; Zhang, Jing-Pu. Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes. International Journal Of Biological Sciences. 13(8):985-995. PubMed - Comments: Used in: ICC |
Wang, Ying; Subramanian, Manikandan; Yurdagul, Arif Jr; Barbosa-Lorenzi, Valéria C; Cai, Bishuang; de Juan-Sanz, Jaime; Ryan, Timothy A; Nomura, Masatoshi; Maxfield, Frederick R; Tabas, Ira. Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages. Cell. 2017;171(2):331-345.e22. PubMed - Comments: Used in: ICC |
Sato, Yusuke; Ohtsubo, Hideaki; Nihei, Naohiro; Kaneko, Takane; Sato, Yoriko; Adachi, Shin-Ichi; Kondo, Shinji; Nakamura, Mako; Mizunoya, Wataru; Iida, Hiroshi; Tatsumi, Ryuichi; Rada, Cristina; Yoshizawa, Fumiaki. Apobec2 deficiency causes mitochondrial defects and mitophagy in skeletal muscle. Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology. 2018;32(3):1428-1439. PubMed - Comments: Used in: WB |
Lee, Pamela P; Lobato-Márquez, Damián; Pramanik, Nayani; Sirianni, Andrea; Daza-Cajigal, Vanessa; Rivers, Elizabeth; Cavazza, Alessia; Bouma, Gerben; Moulding, Dale; Hultenby, Kjell; Westerberg, Lisa S; Hollinshead, Michael; Lau, Yu-Lung; Burns, Siobhan O; Mostowy, Serge; Bajaj-Elliott, Mona; Thrasher, Adrian J. Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells. Nature Communications. 2017;8(1):1576. PubMed - Comments: Used in: WB |
Lee, Pamela P; Lobato-Márquez, Damián; Pramanik, Nayani; Sirianni, Andrea; Daza-Cajigal, Vanessa; Rivers, Elizabeth; Cavazza, Alessia; Bouma, Gerben; Moulding, Dale; Hultenby, Kjell; Westerberg, Lisa S; Hollinshead, Michael; Lau, Yu-Lung; Burns, Siobhan O; Mostowy, Serge; Bajaj-Elliott, Mona; Thrasher, Adrian J. Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells. Nature Communications. 2017;8(1):1576. PubMed - Comments: Used in: ICC |
Yanagisawa, Hiroko; Ishii, Tomohiro; Endo, Kentaro; Kawakami, Emiko; Nagao, Kazuaki; Miyashita, Toshiyuki; Akiyama, Keiko; Watabe, Kazuhiko; Komatsu, Masaaki; Yamamoto, Daisuke; Eto, Yoshikatsu. L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease. Scientific Reports. 2017;7(1):15944. PubMed - Comments: Used in: WB |
Yanagisawa, Hiroko; Ishii, Tomohiro; Endo, Kentaro; Kawakami, Emiko; Nagao, Kazuaki; Miyashita, Toshiyuki; Akiyama, Keiko; Watabe, Kazuhiko; Komatsu, Masaaki; Yamamoto, Daisuke; Eto, Yoshikatsu. L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease. Scientific Reports. 2017;7(1):15944. PubMed - Comments: Used in: ICC |
Hsieh, Chang-Heng; Wang, Jing-Ping; Chiu, Chien-Chih; Liu, Chun-Yen; Yao, Ching-Fa; Fang, Kang. A triazole-conjugated benzoxazone induces reactive oxygen species and promotes autophagic apoptosis in human lung cancer cells. Apoptosis : An International Journal On Programmed Cell Death. 2018;23(1):1-15. PubMed - Comments: Used in: WB |
Prieto-Domínguez, Néstor; Méndez-Blanco, Carolina; Carbajo-Pescador, Sara; Fondevila, Flavia; García-Palomo, Andrés; González-Gallego, Javier; Mauriz, José L. Melatonin enhances sorafenib actions in human hepatocarcinoma cells by inhibiting mTORC1/p70S6K/HIF-1α and hypoxia-mediated mitophagy. Oncotarget. 2017;8(53):91402-91414. PubMed - Comments: Used in: WB |
Mizunoe, Yuhei; Kobayashi, Masaki; Sudo, Yuka; Watanabe, Shukoh; Yasukawa, Hiromine; Natori, Daiki; Hoshino, Ayana; Negishi, Arisa; Okita, Naoyuki; Komatsu, Masaaki; Higami, Yoshikazu. Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways. Redox Biology. 2018;15:115-124. PubMed - Comments: Used in: WB |
Festa, Beatrice Paola; Chen, Zhiyong; Berquez, Marine; Debaix, Huguette; Tokonami, Natsuko; Prange, Jenny Ann; Hoek, Glenn van de; Alessio, Cremonesi; Raimondi, Andrea; Nevo, Nathalie; Giles, Rachel H; Devuyst, Olivier; Luciani, Alessandro. Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney. Nature Communications. 2018;9(1):161. PubMed - Comments: Used in: WB |
Hsu, Cynthia L; Lee, Elian X; Gordon, Kara L; Paz, Edwin A; Shen, Wen-Chuan; Ohnishi, Kohta; Meisenhelder, Jill; Hunter, Tony; La Spada, Albert R. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nature Communications. 2018;9(1):942. PubMed - Comments: Used in: ICC |
Chu, Jiaqi; Fu, Yuanyuan; Xu, Jiecheng; Zheng, Xueping; Gu, Qianqian; Luo, Xia; Dai, Qi; Zhang, Shuxian; Liu, Peiqing; Hong, Liang; Li, Min. ATG4B inhibitor FMK-9a induces autophagy independent on its enzyme inhibition. Archives Of Biochemistry And Biophysics. 2018;644:29-36. PubMed - Comments: Used in: WB |
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Qi, Mengfan; Tian, Ye; Li, Wang; Li, Dan; Zhao, Tian; Yang, Yuxin; Li, Qiwen; Chen, Sujun; Yang, Yan; Zhang, Zhixiong; Tang, Liang; Liu, Zhonghua; Su, Bo; Li, Fei; Feng, Yonghong; Fei, Ke; Zhang, Peng; Zhang, Fan; Zhang, Lei. ERK inhibition represses gefitinib resistance in non-small cell lung cancer cells. Oncotarget. 2018;9(15):12020-12034. PubMed - Comments: Used in: IHC |
Sun, Yan; Huang, Yong-Hao; Huang, Feng-Ying; Mei, Wen-Li; Liu, Quan; Wang, Cai-Chun; Lin, Ying-Ying; Huang, Canhua; Li, Yue-Nan; Dai, Hao-Fu; Tan, Guang-Hong. 3'-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells. Theranostics. 8(7):2044-2060. PubMed - Comments: Used in: WB |
Sun, Yan; Huang, Yong-Hao; Huang, Feng-Ying; Mei, Wen-Li; Liu, Quan; Wang, Cai-Chun; Lin, Ying-Ying; Huang, Canhua; Li, Yue-Nan; Dai, Hao-Fu; Tan, Guang-Hong. 3'-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells. Theranostics. 8(7):2044-2060. PubMed - Comments: Used in: ICC |
El-Darawish, Yosif; Li, Wen; Yamanishi, Kyosuke; Pencheva, Magdalena; Oka, Naoto; Yamanishi, Hiromichi; Matsuyama, Tomohiro; Tanaka, Yoshimasa; Minato, Nagahiro; Okamura, Haruki. Frontline Science: IL-18 primes murine NK cells for proliferation by promoting protein synthesis, survival, and autophagy. Journal Of Leukocyte Biology. 2018;104(2):253-264. PubMed - Comments: Used in: WB |
El-Darawish, Yosif; Li, Wen; Yamanishi, Kyosuke; Pencheva, Magdalena; Oka, Naoto; Yamanishi, Hiromichi; Matsuyama, Tomohiro; Tanaka, Yoshimasa; Minato, Nagahiro; Okamura, Haruki. Frontline Science: IL-18 primes murine NK cells for proliferation by promoting protein synthesis, survival, and autophagy. Journal Of Leukocyte Biology. 2018;104(2):253-264. PubMed - Comments: Used in: ICC |
Ko, Po-Yen; Yang, Cheng-Chang; Kuo, Yao-Lung; Su, Fong-Chin; Hsu, Tai-I; Tu, Yuan-Kun; Jou, I-Ming. Schwann-Cell Autophagy, Functional Recovery, and Scar Reduction After Peripheral Nerve Repair. Journal Of Molecular Neuroscience : Mn. 2018;64(4):601-610. PubMed - Comments: Used in: IHC |
Raulien, Nora; Friedrich, Kathleen; Strobel, Sarah; Rubner, Stefan; Baumann, Sven; von Bergen, Martin; Körner, Antje; Krueger, Martin; Rossol, Manuela; Wagner, Ulf. Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes. Frontiers In Immunology. 8:609. PubMed - Comments: Used in: ICC |
Chen, Bo; Zheng, Yang-Min; Zhang, Jing-Pu. Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish. Frontiers In Endocrinology. 9:366. PubMed - Comments: Used in: WB |
Härtlova, Anetta; Herbst, Susanne; Peltier, Julien; Rodgers, Angela; Bilkei-Gorzo, Orsolya; Fearns, Antony; Dill, Brian D; Lee, Heyne; Flynn, Rowan; Cowley, Sally A; Davies, Paul; Lewis, Patrick A; Ganley, Ian G; Martinez, Jennifer; Alessi, Dario R; Reith, Alastair D; Trost, Matthias; Gutierrez, Maximiliano G. LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. The Embo Journal. 2018;37(12) PubMed - Comments: Used in: ICC |
Phadwal, Kanchan; Kurian, Dominic; Salamat, Muhammad Khalid F; MacRae, Vicky E; Diack, Abigail B; Manson, Jean C. Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates. Scientific Reports. 2018;8(1):10004. PubMed - Comments: Used in: WB |
Phadwal, Kanchan; Kurian, Dominic; Salamat, Muhammad Khalid F; MacRae, Vicky E; Diack, Abigail B; Manson, Jean C. Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates. Scientific Reports. 2018;8(1):10004. PubMed - Comments: Used in: ICC |
Alvarez-Garcia, Oscar; Matsuzaki, Tokio; Olmer, Merissa; Miyata, Kohei; Mokuda, Sho; Sakai, Daisuke; Masuda, Koichi; Asahara, Hiroshi; Lotz, Martin K. FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration. Aging Cell. 2018;17(5):e12800. PubMed - Comments: Used in: IHC |
Sun, Yameng; Zhang, Ting; Zhang, Yan; Li, Jinfeng; Jin, Lei; Sun, Yinyi; Shi, Nan; Liu, Kangyong; Sun, Xiaojiang. Ischemic Postconditioning Alleviates Cerebral Ischemia-Reperfusion Injury Through Activating Autophagy During Early Reperfusion in Rats. Neurochemical Research. 2018;43(9):1826-1840. PubMed - Comments: Used in: WB |
Skah, Seham; Richartz, Nina; Duthil, Eva; Gilljam, Karin M; Bindesbøll, Christian; Naderi, Elin Hallan; Eriksen, Agnete B; Ruud, Ellen; Dirdal, Marta M; Simonsen, Anne; Blomhoff, Heidi Kiil. cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53. Oncotarget. 2018;9(54):30434-30449. PubMed - Comments: Used in: ICC |
Bak, Dong-Ho; Na, Jungtae; Choi, Mi Ji; Lee, Byung Chul; Oh, Chang Taek; Kim, Jeom-Yong; Han, Hae Jung; Kim, Moo Joong; Kim, Tae Ho; Kim, Beom Joon. Anti‑apoptotic effects of human placental hydrolysate against hepatocyte toxicity in vivo and in vitro. International Journal Of Molecular Medicine. 2018;42(5):2569-2583. PubMed - Comments: Used in: WB |
Mohamud, Yasir; Qu, Junyan; Xue, Yuan Chao; Liu, Huitao; Deng, Haoyu; Luo, Honglin. CALCOCO2/NDP52 and SQSTM1/p62 differentially regulate coxsackievirus B3 propagation. Cell Death And Differentiation. 2019;26(6):1062-1076. PubMed - Comments: Used in: WB |
Hagio-Izaki, Kanako; Yasunaga, Madoka; Yamaguchi, Masahiro; Kajiya, Hiroshi; Morita, Hiromitsu; Yoneda, Masahiro; Hirofuji, Takao; Ohno, Jun. Lipopolysaccharide induces bacterial autophagy in epithelial keratinocytes of the gingival sulcus. Bmc Cell Biology. 2018;19(1):18. PubMed - Comments: Used in: WB |
Hagio-Izaki, Kanako; Yasunaga, Madoka; Yamaguchi, Masahiro; Kajiya, Hiroshi; Morita, Hiromitsu; Yoneda, Masahiro; Hirofuji, Takao; Ohno, Jun. Lipopolysaccharide induces bacterial autophagy in epithelial keratinocytes of the gingival sulcus. Bmc Cell Biology. 2018;19(1):18. PubMed - Comments: Used in: ICC |
Ashraf, Naila S; Duarte-Silva, Sara; Shaw, Emily D; Maciel, Patrícia; Paulson, Henry L; Teixeira-Castro, Andreia; Costa, Maria do Carmo. Citalopram Reduces Aggregation of ATXN3 in a YAC Transgenic Mouse Model of Machado-Joseph Disease. Molecular Neurobiology. 2019;56(5):3690-3701. PubMed - Comments: Used in: WB |
Jiao, Yan-Na; Wu, Li-Na; Xue, Dong; Liu, Xi-Juan; Tian, Zhi-Hua; Jiang, Shan-Tong; Han, Shu-Yan; Li, Ping-Ping. Marsdenia tenacissima extract induces apoptosis and suppresses autophagy through ERK activation in lung cancer cells. Cancer Cell International. 18:149. PubMed - Comments: Used in: ICC |
Kim, Jin Kyung; Kim, Yi Sak; Lee, Hye-Mi; Jin, Hyo Sun; Neupane, Chiranjivi; Kim, Sup; Lee, Sang-Hee; Min, Jung-Joon; Sasai, Miwa; Jeong, Jae-Ho; Choe, Seong-Kyu; Kim, Jin-Man; Yamamoto, Masahiro; Choy, Hyon E; Park, Jin Bong; Jo, Eun-Kyeong. GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections. Nature Communications. 2018;9(1):4184. PubMed - Comments: Used in: ICC |
Mori, Hiroyuki; Fukuhara, Takasuke; Ono, Chikako; Tamura, Tomokazu; Sato, Asuka; Fauzyah, Yuzy; Wada, Masami; Okamoto, Toru; Noda, Takeshi; Yoshimori, Tamotsu; Matsuura, Yoshiharu. Induction of selective autophagy in cells replicating hepatitis C virus genome. The Journal Of General Virology. 2018;99(12):1643-1657. PubMed - Comments: Used in: ICC |
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Horibe, Akio; Eid, Nabil; Ito, Yuko; Otsuki, Yoshinori; Kondo, Yoichi. Ethanol-Induced Autophagy in Sertoli Cells Is Specifically Marked at Androgen-Dependent Stages of the Spermatogenic Cycle: Potential Mechanisms and Implications. International Journal Of Molecular Sciences. 2019;20(1) PubMed - Comments: Used in: IHC |
Lu, Shen-Zhao; Guo, Yong-Shun; Liang, Pei-Zhou; Zhang, Shu-Zhen; Yin, Shu; Yin, Yan-Qing; Wang, Xiao-Min; Ding, Fei; Gu, Xiao-Song; Zhou, Jia-Wei. Suppression of astrocytic autophagy by αB-crystallin contributes to α-synuclein inclusion formation. Translational Neurodegeneration. 8:3. PubMed - Comments: Used in: WB |
Lu, Shen-Zhao; Guo, Yong-Shun; Liang, Pei-Zhou; Zhang, Shu-Zhen; Yin, Shu; Yin, Yan-Qing; Wang, Xiao-Min; Ding, Fei; Gu, Xiao-Song; Zhou, Jia-Wei. Suppression of astrocytic autophagy by αB-crystallin contributes to α-synuclein inclusion formation. Translational Neurodegeneration. 8:3. PubMed - Comments: Used in: IHC |
Schulthess, Julie; Pandey, Sumeet; Capitani, Melania; Rue-Albrecht, Kevin C; Arnold, Isabelle; Franchini, Fanny; Chomka, Agnieszka; Ilott, Nicholas E; Johnston, Daniel G W; Pires, Elisabete; McCullagh, James; Sansom, Stephen N; Arancibia-Cárcamo, Carolina V; Uhlig, Holm H; Powrie, Fiona. The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages. Immunity. 2019;50(2):432-445.e7. PubMed - Comments: Used in: ICC |
Ma, Biao; Cheng, Hongcheng; Mu, Chenglong; Geng, Guangfeng; Zhao, Tian; Luo, Qian; Ma, Kaili; Chang, Rui; Liu, Qiangqiang; Gao, Ruize; Nie, Junli; Xie, Jiaying; Han, Jinxue; Chen, Linbo; Ma, Gui; Zhu, Yushan; Chen, Quan. The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression. Nature Communications. 2019;10(1):1034. PubMed - Comments: Used in: WB |
Ma, Biao; Cheng, Hongcheng; Mu, Chenglong; Geng, Guangfeng; Zhao, Tian; Luo, Qian; Ma, Kaili; Chang, Rui; Liu, Qiangqiang; Gao, Ruize; Nie, Junli; Xie, Jiaying; Han, Jinxue; Chen, Linbo; Ma, Gui; Zhu, Yushan; Chen, Quan. The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression. Nature Communications. 2019;10(1):1034. PubMed - Comments: Used in: ICC |
Hsu, Yung-Ho; Chuang, Hsiao-Chi; Lee, Yu-Hsuan; Lin, Yuh-Feng; Chen, Yi-Jie; Hsiao, Ta-Chih; Wu, Mei-Yi; Chiu, Hui-Wen. Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo. Free Radical Biology & Medicine. 2019;135:235-244. PubMed - Comments: Used in: WB |
Hsu, Yung-Ho; Chuang, Hsiao-Chi; Lee, Yu-Hsuan; Lin, Yuh-Feng; Chen, Yi-Jie; Hsiao, Ta-Chih; Wu, Mei-Yi; Chiu, Hui-Wen. Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo. Free Radical Biology & Medicine. 2019;135:235-244. PubMed - Comments: Used in: IHC |
Nakajima, Shinsuke; Nishimoto, Yuki; Tateya, Sanshiro; Iwahashi, Yasuyuki; Okamatsu-Ogura, Yuko; Saito, Masayuki; Ogawa, Wataru; Tamori, Yoshikazu. Fat-specific protein 27α inhibits autophagy-dependent lipid droplet breakdown in white adipocytes. Journal Of Diabetes Investigation. 2019;10(6):1419-1429. PubMed - Comments: Used in: IF |
Eid, Nabil; Ito, Yuko; Horibe, Akio; Otsuki, Yoshinori; Kondo, Yoichi. Ethanol-Induced Mitochondrial Damage in Sertoli Cells is Associated with Parkin Overexpression and Activation of Mitophagy. Cells. 2019;8(3) PubMed - Comments: Used in: WB |
Eid, Nabil; Ito, Yuko; Horibe, Akio; Otsuki, Yoshinori; Kondo, Yoichi. Ethanol-Induced Mitochondrial Damage in Sertoli Cells is Associated with Parkin Overexpression and Activation of Mitophagy. Cells. 2019;8(3) PubMed - Comments: Used in: IHC |
Eid, Nabil; Ito, Yuko; Horibe, Akio; Otsuki, Yoshinori; Kondo, Yoichi. Ethanol-Induced Mitochondrial Damage in Sertoli Cells is Associated with Parkin Overexpression and Activation of Mitophagy. Cells. 2019;8(3) PubMed |
Ding, Xianming; Jiang, Xiao; Tian, Rui; Zhao, Pengwei; Li, Lin; Wang, Xinyi; Chen, She; Zhu, Yushan; Mei, Mei; Bao, Shilai; Liu, Wei; Tang, Zaiming; Sun, Qiming. RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells. Autophagy. 2019;15(10):1774-1786. PubMed - Comments: Used in: WB |
Ding, Xianming; Jiang, Xiao; Tian, Rui; Zhao, Pengwei; Li, Lin; Wang, Xinyi; Chen, She; Zhu, Yushan; Mei, Mei; Bao, Shilai; Liu, Wei; Tang, Zaiming; Sun, Qiming. RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells. Autophagy. 2019;15(10):1774-1786. PubMed - Comments: Used in: ICC |
Slowicka, Karolina; Serramito-Gómez, Inmaculada; Boada-Romero, Emilio; Martens, Arne; Sze, Mozes; Petta, Ioanna; Vikkula, Hanna K; De Rycke, Riet; Parthoens, Eef; Lippens, Saskia; Savvides, Savvas N; Wullaert, Andy; Vereecke, Lars; Pimentel-Muiños, Felipe X; van Loo, Geert. Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis. Nature Communications. 2019;10(1):1834. PubMed - Comments: Used in: WB |
Abdullah, Amar; Zhang, Moses; Frugier, Tony; Bedoui, Sammy; Taylor, Juliet M; Crack, Peter J. STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury. Journal Of Neuroinflammation. 2018;15(1):323. PubMed - Comments: Used in: WB |
Wei, Ran; Enaka, Mayu; Muragaki, Yasuteru. Activation of KEAP1/NRF2/P62 signaling alleviates high phosphate-induced calcification of vascular smooth muscle cells by suppressing reactive oxygen species production. Scientific Reports. 2019;9(1):10366. PubMed - Comments: Used in: WB |
Nakashima, Akitoshi; Cheng, Shi-Bin; Kusabiraki, Tae; Motomura, Kenichiro; Aoki, Aiko; Ushijima, Akemi; Ono, Yosuke; Tsuda, Sayaka; Shima, Tomoko; Yoshino, Osamu; Sago, Haruhiko; Matsumoto, Kenji; Sharma, Surendra; Saito, Shigeru. Endoplasmic reticulum stress disrupts lysosomal homeostasis and induces blockade of autophagic flux in human trophoblasts. Scientific Reports. 2019;9(1):11466. PubMed - Comments: Used in: ICC |
Nakashima, Akitoshi; Cheng, Shi-Bin; Kusabiraki, Tae; Motomura, Kenichiro; Aoki, Aiko; Ushijima, Akemi; Ono, Yosuke; Tsuda, Sayaka; Shima, Tomoko; Yoshino, Osamu; Sago, Haruhiko; Matsumoto, Kenji; Sharma, Surendra; Saito, Shigeru. Endoplasmic reticulum stress disrupts lysosomal homeostasis and induces blockade of autophagic flux in human trophoblasts. Scientific Reports. 2019;9(1):11466. PubMed - Comments: Used in: WB |
Gao, Likun; Wang, Zhi; Lu, Danhua; Huang, Jinling; Liu, Jin; Hong, Li. Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells. Cell Death & Disease. 2019;10(8):609. PubMed - Comments: Used in: WB |
Dai, Anbang; Yu, Li; Wang, Hong-Wei. WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes. Nature Communications. 2019;10(1):3699. PubMed - Comments: Used in: WB |
Zhou, Jiali; Kang, Xincong; Luo, Yushuang; Yuan, Yuju; Wu, Yanyang; Wang, Meijun; Liu, Dongbo. Glibenclamide-Induced Autophagy Inhibits Its Insulin Secretion-Improving Function in β Cells. International Journal Of Endocrinology. 2019:1265175. PubMed - Comments: Used in: WB |
Kozako, Tomohiro; Aikawa, Akiyoshi; Ohsugi, Takeo; Uchida, Yu-Ichiro; Kato, Naho; Sato, Keisuke; Ishitsuka, Kenji; Yoshimitsu, Makoto; Honda, Shin-Ichiro. High expression of NAMPT in adult T-cell leukemia/lymphoma and anti-tumor activity of a NAMPT inhibitor. European Journal Of Pharmacology. 2019;865:172738. PubMed - Comments: Used in: WB |
Kondo, Saki; Fukazawa, Ayumi; Karasawa, Takuya; Terada, Shin. Effects of long-term exercise training for different durations on pancreatic amylase activity and intestinal glucose transporter content in rats. Physiological Reports. 2019;7(20):e14255. PubMed - Comments: Used in: WB |
Sun, Xiaolei; Wu, Anguo; Kwan Law, Betty Yuen; Liu, Chaolin; Zeng, Wu; Ling Qiu, Alena Cong; Han, Yu; He, Yanzheng; Wai Wong, Vincent Kam. The active components derived from Penthorum chinensePursh protect against oxidative-stress-induced vascular injury via autophagy induction. Free Radical Biology & Medicine. 2020;146:160-180. PubMed - Comments: Used in: WB |
Nettesheim, April; Shim, Myoung Sup; Hirt, Josh; Liton, Paloma B. Transcriptome analysis reveals autophagy as regulator of TGFβ/Smad-induced fibrogenesis in trabecular meshwork cells. Scientific Reports. 2019;9(1):16092. PubMed - Comments: Used in: WB |
Scotto Rosato, A; Montefusco, S; Soldati, C; Di Paola, S; Capuozzo, A; Monfregola, J; Polishchuk, E; Amabile, A; Grimm, C; Lombardo, A; De Matteis, M A; Ballabio, A; Medina, D L. TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway. Nature Communications. 2019;10(1):5630. PubMed - Comments: Used in: IF |
Jang, Hanbit; Park, Seulki; Kim, Jaehoon; Kim, Jong Hwan; Kim, Seon-Young; Cho, Sayeon; Park, Sung Goo; Park, Byoung Chul; Kim, Sunhong; Kim, Jeong-Hoon. The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNAInduced Silencing of NF-κB-Inducing Kinase. Molecules And Cells. 2020;43(1):23-33. PubMed - Comments: Used in: WB |
Nakamura, Takemasa; Shimizu, Takashi; Uda, Akihiko; Watanabe, Kenta; Watarai, Masahisa. Soluble lytic transglycosylase SLT of Francisella novicida is involved in intracellular growth and immune suppression. Plos One. 14(12):e0226778. PubMed - Comments: Used in: ICC |
Omi, Jumpei; Watanabe-Takahashi, Miho; Igai, Katsura; Shimizu, Eiko; Tseng, Ching-Yi; Miyasaka, Tomohiro; Waku, Tsuyoshi; Hama, Shinichiro; Nakanishi, Rieka; Goto, Yuki; Nishino, Yuri; Miyazawa, Atsuo; Natori, Yasuhiro; Yamashita, Makoto; Nishikawa, Kiyotaka. The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection. Nature Communications. 2020;11(1):162. PubMed - Comments: Used in: ICC |
Ye, Xiaoxia; Zhu, Mingming; Che, Xiaohang; Wang, Huiyang; Liang, Xing-Jie; Wu, Chunfu; Xue, Xue; Yang, Jingyu. Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation. Journal Of Neuroinflammation. 2020;17(1):18. PubMed - Comments: Used in: WB |
Boukhalfa, Asma; Nascimbeni, Anna Chiara; Ramel, Damien; Dupont, Nicolas; Hirsch, Emilio; Gayral, Stephanie; Laffargue, Muriel; Codogno, Patrice; Morel, Etienne. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nature Communications. 2020;11(1):294. PubMed - Comments: Used in: IHC |
He, Xiu; Chen, Shi; Li, Chao; Ban, Jiaqi; Wei, Yungeng; He, Yangyang; Liu, Fangwei; Chen, Ying; Chen, Jie. Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages. Cells. 2020;9(1) PubMed - Comments: Used in: WB |
Ogawa-Akiyama, Ayu; Sugiyama, Hitoshi; Kitagawa, Masashi; Tanaka, Keiko; Kano, Yuzuki; Mise, Koki; Otaka, Nozomu; Tanabe, Katsuyuki; Morinaga, Hiroshi; Kinomura, Masaru; Uchida, Haruhito A; Wada, Jun. Podocyte autophagy is associated with foot process effacement and proteinuria in patients with minimal change nephrotic syndrome. Plos One. 15(1):e0228337. PubMed - Comments: Used in: IHC |
Dong, S; Aguirre-Hernandez, C; Scrivo, A; Eliscovich, C; Arias, E; Bravo-Cordero, J J; Cuervo, A M. Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo. Nature Communications. 2020;11(1):645. PubMed - Comments: Used in: ICC |
Siedlecka-Kroplewska, K; Wozniak, M; Kmiec, Z. The wine polyphenol resveratrol modulates autophagy and induces apoptosis in MOLT-4 and HL-60 human leukemia cells. Journal Of Physiology And Pharmacology : An Official Journal Of The Polish Physiological Society. 2019;70(6) PubMed - Comments: Used in: WB |
Siedlecka-Kroplewska, K; Wozniak, M; Kmiec, Z. The wine polyphenol resveratrol modulates autophagy and induces apoptosis in MOLT-4 and HL-60 human leukemia cells. Journal Of Physiology And Pharmacology : An Official Journal Of The Polish Physiological Society. 2019;70(6) PubMed - Comments: Used in: ICC |
Luciani, Alessandro; Schumann, Anke; Berquez, Marine; Chen, Zhiyong; Nieri, Daniela; Failli, Mario; Debaix, Huguette; Festa, Beatrice Paola; Tokonami, Natsuko; Raimondi, Andrea; Cremonesi, Alessio; Carrella, Diego; Forny, Patrick; Kölker, Stefan; Diomedi Camassei, Francesca; Diaz, Francisca; Moraes, Carlos T; Di Bernardo, Diego; Baumgartner, Matthias R; Devuyst, Olivier. Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nature Communications. 2020;11(1):970. PubMed - Comments: Used in: WB |
Luciani, Alessandro; Schumann, Anke; Berquez, Marine; Chen, Zhiyong; Nieri, Daniela; Failli, Mario; Debaix, Huguette; Festa, Beatrice Paola; Tokonami, Natsuko; Raimondi, Andrea; Cremonesi, Alessio; Carrella, Diego; Forny, Patrick; Kölker, Stefan; Diomedi Camassei, Francesca; Diaz, Francisca; Moraes, Carlos T; Di Bernardo, Diego; Baumgartner, Matthias R; Devuyst, Olivier. Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency. Nature Communications. 2020;11(1):970. PubMed - Comments: Used in: IF |
Marubashi, Soujiro; Fukuda, Mitsunori. Rab7B/42 Is Functionally Involved in Protein Degradation on Melanosomes in Keratinocytes. Cell Structure And Function. 2020;45(1):45-55. PubMed - Comments: Used in: WB |
Lee, Jina; Choi, Jae-Won; Han, Hye Young; Kim, Woo Sik; Song, Ha-Yeon; Byun, Eui-Baek; Byun, Eui-Hong; Lee, Young-Ha; Yuk, Jae-Min. 4-Hydroxybenzaldehyde Restricts the Intracellular Growth of Toxoplasma gondii by Inducing SIRT1-Mediated Autophagy in Macrophages. The Korean Journal Of Parasitology. 2020;58(1):7-14. PubMed - Comments: Used in: IF |
Nerome, Kuniaki; Ito-Kureha, Taku; Paganini, Tiziana; Fukuda, Takao; Igarashi, Yasuhiro; Ashitomi, Hiroto; Ikematsu, Shinya; Yamamoto, Tadashi. Potent and broad anticancer activities of leaf extracts from Melia azedarach L. of the subtropical Okinawa islands. American Journal Of Cancer Research. 10(2):581-594. PubMed - Comments: Used in: WB |
Kido, Kohki; Yamanaka, Satoshi; Nakano, Shogo; Motani, Kou; Shinohara, Souta; Nozawa, Akira; Kosako, Hidetaka; Ito, Sohei; Sawasaki, Tatsuya. AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions. Elife. 2020;9 PubMed - Comments: Used in: IP |
Kurashige, Tomomi; Nakajima, Yasuyo; Shimamura, Mika; Yamada, Masanobu; Nagayama, Yuji. Hormonal Regulation of Autophagy in Thyroid PCCL3 Cells and the Thyroids of Male Mice. Journal Of The Endocrine Society. 2020;4(7):bvaa054. PubMed - Comments: Used in: IF |
Kurashige, Tomomi; Nakajima, Yasuyo; Shimamura, Mika; Yamada, Masanobu; Nagayama, Yuji. Hormonal Regulation of Autophagy in Thyroid PCCL3 Cells and the Thyroids of Male Mice. Journal Of The Endocrine Society. 2020;4(7):bvaa054. PubMed - Comments: Used in: IHC |
Kurashige, Tomomi; Nakajima, Yasuyo; Shimamura, Mika; Yamada, Masanobu; Nagayama, Yuji. Hormonal Regulation of Autophagy in Thyroid PCCL3 Cells and the Thyroids of Male Mice. Journal Of The Endocrine Society. 2020;4(7):bvaa054. PubMed - Comments: Used in: WB |
Chen, Cheng; Liu, Li; Shu, Ya-Qiao; Jing, Ping; Lu, Yun; Zhang, Xiao-Xue; Zong, Xian-Gang; Guo, Lian-Jun; Li, Chang-Jun. Blockade of HCN2 Channels Provides Neuroprotection Against Ischemic Injury via Accelerating Autophagic Degradation in Hippocampal Neurons. Neuroscience Bulletin. 2020;36(8):875-894. PubMed - Comments: Used in: WB |
Chen, Cheng; Liu, Li; Shu, Ya-Qiao; Jing, Ping; Lu, Yun; Zhang, Xiao-Xue; Zong, Xian-Gang; Guo, Lian-Jun; Li, Chang-Jun. Blockade of HCN2 Channels Provides Neuroprotection Against Ischemic Injury via Accelerating Autophagic Degradation in Hippocampal Neurons. Neuroscience Bulletin. 2020;36(8):875-894. PubMed - Comments: Used in: IF |
Nettesheim, April; Dixon, Angela; Shim, Myoung Sup; Coyne, Aislyn; Walsh, Molly; Liton, Paloma B. Autophagy in the Aging and Experimental Ocular Hypertensive Mouse Model. Investigative Ophthalmology & Visual Science. 2020;61(10):31. PubMed - Comments: Used in: IF |
Lee, Ying-Ray; Wu, Shan-Ying; Chen, Ruei-Yi; Lin, Yee-Shin; Yeh, Trai-Ming; Liu, Hsiao-Sheng. Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection. The Kaohsiung Journal Of Medical Sciences. 2020;36(11):911-919. PubMed - Comments: Used in: WB |
Bosc, Claudie; Broin, Nicolas; Fanjul, Marjorie; Saland, Estelle; Farge, Thomas; Courdy, Charly; Batut, Aurélie; Masoud, Rawand; Larrue, Clément; Skuli, Sarah; Espagnolle, Nicolas; Pagès, Jean-Christophe; Carrier, Alice; Bost, Frédéric; Bertrand-Michel, Justine; Tamburini, Jérôme; Récher, Christian; Bertoli, Sarah; Mansat-De Mas, Véronique; Manenti, Stéphane; Sarry, Jean-Emmanuel; Joffre, Carine. Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites. Nature Communications. 2020;11(1):4056. PubMed - Comments: Used in: IF |
Yamamuro, Tadashi; Kawabata, Tsuyoshi; Fukuhara, Atsunori; Saita, Shotaro; Nakamura, Shuhei; Takeshita, Hikari; Fujiwara, Mari; Enokidani, Yusuke; Yoshida, Gota; Tabata, Keisuke; Hamasaki, Maho; Kuma, Akiko; Yamamoto, Koichi; Shimomura, Iichiro; Yoshimori, Tamotsu. Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. Nature Communications. 2020;11(1):4150. PubMed - Comments: Used in: WB |
Gentile, Debora; Berliocchi, Laura; Russo, Rossella; Bagetta, Giacinto; Corasaniti, Maria Tiziana. Effects of the autophagy modulators d-limonene and chloroquine on vimentin levels in SH-SY5Y cells. Biochemical And Biophysical Research Communications. 2020;533(4):764-769. PubMed - Comments: Used in: WB |
Sakane, Hiroshi; Urabe, Junna; Nakahira, Saki; Hino, Katsumi; Miyata, Nao; Akasaki, Kenji. Involvement of lysosomal integral membrane protein-2 in the activation of autophagy. Biochemical And Biophysical Research Communications. 2020;533(4):976-982. PubMed - Comments: Used in: WB |
Setua, Sonali; Enguita, Francisco J; Chora, Ângelo Ferreira; Ranga-Prasad, Harish; Lahree, Aparajita; Marques, Sofia; Sundaramurthy, Varadharajan; Mota, Maria M. Disrupting Plasmodium UIS3-host LC3 interaction with a small molecule causes parasite elimination from host cells. Communications Biology. 2020;3(1):688. PubMed - Comments: Used in: WB |
Nozaki, Masahisa; Otomo, Asako; Mitsui, Shun; Ono, Suzuka; Shirakawa, Ryohei; Chen, YongPing; Hama, Yutaro; Sato, Kai; Chen, XuePing; Suzuki, Toshiyasu; Shang, Hui-Fang; Hadano, Shinji. SQSTM1(L341V) variant that is linked to sporadic ALS exhibits impaired association with MAP1LC3 in cultured cells. Eneurologicalsci. 2021;22:100301. PubMed - Comments: Used in: ICC |