Application: IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
| Documents & Links for Anti HP mAb (Clone 5A5) | |
| Datasheet | Anti HP mAb (Clone 5A5) Datasheet |
| Vendor Page | Anti HP mAb (Clone 5A5) at CUSABIO |
| Documents & Links for Anti HP mAb (Clone 5A5) | |
| Datasheet | Anti HP mAb (Clone 5A5) Datasheet |
| Vendor Page | Anti HP mAb (Clone 5A5) |
