Anti HLA Class I-A, B, C mAb (Clone EMR8-5, Biotin Labeled)

Cosmo Bio LTD

Catalog No: HKD-AB-46-B

Application: IHC, WB 
Clonality: Monoclonal 
Conjugation: Biotin 
Host: Mouse 
Reactivity: Human 

Quantity: 100 µL/vial (1 mg/mL) Clone: EMR8-5 Isotype: IgG1
Buffer: Phosphate buffered saline pH7.4, 0.05% Sodium Azide
Immunogen: recombinant HLA-A*2402 extracellular domain Specificity: Heavy chains of HLA-A, HLA-B, HLA-C
Applications: Immunohistochemistry (formalin-fixed tissue) Western blotting Optimal dilutions/concentrations should be determined by the user.
Storage: Store at 2 ~ 8°C. Do not freeze.

References:
1. Torigoe T, Asanuma H, Shimozawa K, et al. Immunohistochemical analysis of HLA class I expression in tumor tissues revealed unusually high frequency of down-regulation in breast cancer tissues. submitted
2. Tsukahara T, Kawaguchi S, Torigoe T, et al Prognostic significance of HLA class I expression in osteosarcoma defined by anti-pan HLA class I monoclonal antibody, EMR8-5. Cancer Sci 97: 1374-1380, 2006
3. Kitamura H, Torigoe T, Honma I, et al Effect of human leukocyte antigen class I expression of tumor cells on outcome of intravesical instillation of bacillus calmette-guerin immunotherapy for bladder cancer. Clin Cancer Res 12: 4641-4644, 2006
4. Komori H, Nakatsura T, Senju S, et al Identification of HLA-A2- or HLA-A24-restricted CTL epitopes possibly useful for glypican-3-specific immunotherapy of hepatocellular carcinoma. Clin Cancer Res 12: 2689-2697, 2006.
5. Kitamura H, Torigoe T, Honma I, et al Expression and antigenicity of survivin, an inhibitor of apoptosis family member, in bladder cancer: implications for specific immunotherapy. Urology 67: 955-959, 2006