Hepatitis B virus (HBV) expresses three types of surface antigens, i.e. S-, M-, and L-protein. L-protein is composed of S-, Pre-S2, and Pre-S1 region. The deletion of Pre-S1 region forms M-protein and further deletion of Pre-S2 region results in S-protein. So calledHBsAg is composed of either S-protein alone or a mixture of S-and M-proteins. The Pre-S1 region is known to be the hepatic cell recognition site and to be important in the HBV infection and Pre-S2 isreportedly known to related HBV entry or carcinogenesis. Pre-S2 region is known to have variation of amino acid sequence depending on genotypes.
Product Specifications
Application
WB, ELISA
Clonality
Monoclonal (Clone No.: 88F3)
Host
Mouse
Documents & Links for Anti-HBs, Pre-S2 mAb (Clone 88F3)
