Anti GMNN pAb (ATL-HPA049977 w/enhanced validation)

Catalog No:
ATL-HPA049977-25
$390.00
Application: ICC, IHC 
Clonality: Polyclonal 
Host: Rabbit 
Reactivity: Human 
Protein Description: geminin, DNA replication inhibitor
Gene Name: GMNN
Alternative Gene Name: Gem
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000006715: 90%, ENSRNOG00000018782: 88%
Entrez Gene ID: 51053
Uniprot ID: O75496
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Cognate Antibody/Antigen for Anti GMNN pAb (ATL-HPA049977 w/enhanced validation)
Antigen PrEST Antigen GMNN (ATL-APrEST85402)
Documents & Links for Anti GMNN pAb (ATL-HPA049977 w/enhanced validation)
Datasheet Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) at Atlas

Documents & Links for Anti GMNN pAb (ATL-HPA049977 w/enhanced validation)
Datasheet Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti GMNN pAb (ATL-HPA049977 w/enhanced validation)

Citations for Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) – 4 Found
Irreversible APC(Cdh1) Inactivation Underlies the Point of No Return for Cell-Cycle Entry.
Cell. 2016 Jun 30;166(1):167-80. doi: 10.1016/j.cell.2016.05.077.  PubMed
EMI1 switches from being a substrate to an inhibitor of APC/C(CDH1) to start the cell cycle.
Nature. 2018 Jun;558(7709):313-317. doi: 10.1038/s41586-018-0199-7. Epub 2018 Jun 6.  PubMed
Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity.
Nat Commun. 2020 Oct 20;11(1):5305. doi: 10.1038/s41467-020-18966-9.  PubMed
CDC7-independent G1/S transition revealed by targeted protein degradation.
Nature. 2022 May;605(7909):357-365. doi: 10.1038/s41586-022-04698-x. Epub 2022 May 4.  PubMed