Application: ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: geminin, DNA replication inhibitor
Gene Name: GMNN
Alternative Gene Name: Gem
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000006715: 90%, ENSRNOG00000018782: 88%
Entrez Gene ID: 51053
Uniprot ID: O75496
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: geminin, DNA replication inhibitor
Gene Name: GMNN
Alternative Gene Name: Gem
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000006715: 90%, ENSRNOG00000018782: 88%
Entrez Gene ID: 51053
Uniprot ID: O75496
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Cognate Antibody/Antigen for Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) | |
Antigen | PrEST Antigen GMNN (ATL-APrEST85402) |
Documents & Links for Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) | |
Datasheet | Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) Datasheet (External Link) |
Vendor Page | Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) at Atlas |
Documents & Links for Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) | |
Datasheet | Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) Datasheet (External Link) |
Vendor Page | Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) |
Citations for Anti GMNN pAb (ATL-HPA049977 w/enhanced validation) – 4 Found |
Irreversible APC(Cdh1) Inactivation Underlies the Point of No Return for Cell-Cycle Entry. Cell. 2016 Jun 30;166(1):167-80. doi: 10.1016/j.cell.2016.05.077. PubMed |
EMI1 switches from being a substrate to an inhibitor of APC/C(CDH1) to start the cell cycle. Nature. 2018 Jun;558(7709):313-317. doi: 10.1038/s41586-018-0199-7. Epub 2018 Jun 6. PubMed |
Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity. Nat Commun. 2020 Oct 20;11(1):5305. doi: 10.1038/s41467-020-18966-9. PubMed |
CDC7-independent G1/S transition revealed by targeted protein degradation. Nature. 2022 May;605(7909):357-365. doi: 10.1038/s41586-022-04698-x. Epub 2022 May 4. PubMed |