Anti FLNA mAb (Clone 1B2)

CUSABIO

Catalog No.:
CSB-RA548809A0HU-50
IHC image of CSB-RA548809A0HU diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
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Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).

Product Specifications
Application IHC, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 1B2)

Documents & Links for Anti FLNA mAb (Clone 1B2)
Datasheet Anti FLNA mAb (Clone 1B2) Datasheet

Documents & Links for Anti FLNA mAb (Clone 1B2)
Datasheet Anti FLNA mAb (Clone 1B2) Datasheet
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