IHC image of CSB-RA787345A0HU diluted at 1:100 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Anti FBP1 mAb (Clone 4G3)

Catalog No:
CSB-RA787345A0HU-50
$210.00
Application: IHC, ELISA 
Clonality: Monoclonal 
Purification: Purified - Affinity 
Reactivity: Human 
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Documents & Links for Anti FBP1 mAb (Clone 4G3)
DatasheetAnti FBP1 mAb (Clone 4G3) Datasheet
Vendor PageAnti FBP1 mAb (Clone 4G3) at CUSABIO

Documents & Links for Anti FBP1 mAb (Clone 4G3)
DatasheetAnti FBP1 mAb (Clone 4G3) Datasheet
Vendor PageAnti FBP1 mAb (Clone 4G3)