Application: WB, IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
| Documents & Links for Anti FAS mAb (Clone 2B6) | |
| Datasheet | Anti FAS mAb (Clone 2B6) Datasheet |
| Vendor Page | Anti FAS mAb (Clone 2B6) at CUSABIO |
| Documents & Links for Anti FAS mAb (Clone 2B6) | |
| Datasheet | Anti FAS mAb (Clone 2B6) Datasheet |
| Vendor Page | Anti FAS mAb (Clone 2B6) |
