Background
CAP-H2 is regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture.INI1/BAF47/SNF5 is a core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal.
Application
Western blotting, 1/1,000 to 1/5,000
Immunocytochemistry, 1/500
Immunohistochemistry, 1/100 to 1/500
Antigen/Source
CAP-H2 (Condensin II subunit)
Host
Rat
Immunogen
Human
Reacts with
Human/Monkey
Clone
5F2G4
Isotype
IgG2a
Applications
Western Blot/Immunocytochemistry (cell)/Immunoprecipitation
Preservative
0.05% NaN3 in LIQ
Storage
-70C
References
1) Wood et al. (2010) Nat. Rev. Genet. 11:391-404.
Product Specifications
Application
IP, ICC, WB, IF
Reactivity
Mouse, Human
Clonality
Monoclonal (Clone No.: 5F2G4)
Host
Rat
Documents & Links for Anti Condensin-2 Complex Subunit H2 (CAP-H2) mAb (Clone 5F2G4)
