Anti CLK2 pAb (ATL-HPA055366)

Atlas Antibodies

SKU: ATL-HPA055366-100

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Protein Description: CDC-like kinase 2
Gene Name: CLK2
Alternative Gene Name: clk2
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000068917: 95%, ENSRNOG00000020500: 95%
Entrez Gene ID: 1196
Uniprot ID: P49760
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: HPRRYHSSERGSRGSYREHYRSRKHKRRRSRSWSSSSDRTRRRRREDSYHVRSRSSYDDRSSDR
• Gene Sequence: HPRRYHSSERGSRGSYREHYRSRKHKRRRSRSWSSSSDRTRRRRREDSYHVRSRSSYDDRSSDR
• Gene ID - Mouse: ENSMUSG00000068917
• Gene ID - Rat: ENSRNOG00000020500
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti CLK2 pAb (ATL-HPA055366) – 3 Found

Tiek, Deanna M; Erdogdu, Beril; Razaghi, Roham; Jin, Lu; Sadowski, Norah; Alamillo-Ferrer, Carla; Hogg, J Robert; Haddad, Bassem R; Drewry, David H; Wells, Carrow I; Pickett, Julie E; Song, Xiao; Goenka, Anshika; Hu, Bo; Goldlust, Samuel A; Zuercher, William J; Pertea, Mihaela; Timp, Winston; Cheng, Shi-Yuan; Riggins, Rebecca B. Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas. Science Advances. 2022;8(25):eabn3471. 

Park, Soon Young; Piao, Yuji; Thomas, Craig; Fuller, Gregory N; de Groot, John F. Cdc2-like kinase 2 is a key regulator of the cell cycle via FOXO3a/p27 in glioblastoma. Oncotarget. 2016;7(18):26793-805. 

Park, Soon Young; Mittal, Sandeep; Dong, Jianwen; Jeong, Kangjin; Martinez-Ledesma, Emmanuel; Piao, Yuji; Khan, Sabbir; Henry, Verlene; Verhaak, Roel Gw; Majd, Nazanin; Balasubramaniyan, Veerakumar; de Groot, John F. Depletion of CLK2 sensitizes glioma stem-like cells to PI3K/mTOR and FGFR inhibitors. American Journal Of Cancer Research. 10(11):3765-3783.