Application: IF, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.
| Documents & Links for Anti ADAM17 mAb (Clone 5A1) | |
| Datasheet | Anti ADAM17 mAb (Clone 5A1) Datasheet |
| Vendor Page | Anti ADAM17 mAb (Clone 5A1) at CUSABIO |
| Documents & Links for Anti ADAM17 mAb (Clone 5A1) | |
| Datasheet | Anti ADAM17 mAb (Clone 5A1) Datasheet |
| Vendor Page | Anti ADAM17 mAb (Clone 5A1) |
