Application: WB, IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Documents & Links for Anti ACVRL1 mAb (Clone 8B6) | |
Datasheet | Anti ACVRL1 mAb (Clone 8B6) Datasheet |
Vendor Page | Anti ACVRL1 mAb (Clone 8B6) at CUSABIO |
Documents & Links for Anti ACVRL1 mAb (Clone 8B6) | |
Datasheet | Anti ACVRL1 mAb (Clone 8B6) Datasheet |
Vendor Page | Anti ACVRL1 mAb (Clone 8B6) |