Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
| Product Specifications |
| Application |
WB, IHC, ELISA |
| Reactivity |
Human |
| Clonality |
Monoclonal (Clone No.: 8B6) |
