Custom MHC tetramer services - MHC Class II custom Tetramer

We can manufacture a custom MHC tetramer of your interest.

Available alleles

Human Class II

DRB1*01:01

DRB1*04:01
DRB1*04:10
DRB1*04:05
DRB1*07:01
DRB1*08:02
DRB1*08:03
DRB1*09:01

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DRB1*14:06
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DRB1*15:02
DRB4*01:01

Steps for manufacturing MHC class II tetramer

Folding test

When we conduct Folding tests, we set a standard for ability to form MHC-peptide complex. The standard point is when the difference in retention time (the time at which the target protein peak appears by HPLC) between the control peptide and the specified peptide is 0.1 min or more.

Human HLA class II Tetramer custom order

We require a minimum of 20 mgs. Peptide purity must be greater than or equal to 90%. Please ship freeze-dried peptide.
If we cannot obtain enough monomer for tetramerization, we have no use to quit the task. In this case, we will send you a work report instead of the product.

If you have any interest in our custom-made tetramers or monomers, please do not hesitate to contact our support desk.