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Connecting in vitro experiments to in vivo experiments with 3D culture and oligonucleotides delivery technologies

NEW PRODUCTS

     FibColl® Atelocollagen Inserts 24
     3D Honeycomb Boosted
     3D Ready Atelocollagen


Atelocollagen / Native Collagen Acidic Solutions
Atelocollagen Neutral Solutions
Atelocollagen, Honeycomb Sponge
Atelocollagen Sponge, MIGHTY
Atelocollagen Coated B-TCP Scaffold
Atelocollagen Microspheres
Collagen Sponge for 35 mm Culture Dish
Atelocollagen, Permeable Membrane for 50 mm Culture Dish
Atelocollagen, Permeable Membrane for 6-well, 24-well Culture Plate
Type II Collagen
Atelocollagen Powder, Membrane, Sponge

All Products 

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3D Ready Atelocollagen

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 3D Culture  Culture on collagen gel Co-culture 
  • Ready-to-use atelocollagen solution for 3D culture.
  • Premixed with DMEM, low glucose or high glucose.
  • Easy operation: simply mix with the cells and warm to form a gel.
  • Reduces cell sedimentation during gel formation achieves a stable 3D culture. Learn More

 

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Atelocollagen / Native Collagen Acidic Solutions

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Collagen coating  3D Culture  Culture on collagen gel Co-culture 
  • Atelocollagen/Native collagen acidic solutions form a gel (fibrillisation) under physiological conditions.
  • Collagen concentrations of 3 mg/mL and 5 mg/mL are available and are suitable for coating and preparing gel as a scaffold for 3D culture applications, respectively.
  • In contrast to cell-derived soluble basement membrane preparations, collagen solutions are free from bioactive compounds, nucleic acids, matrix metalloprotease (MMP), etc., allowing experimental results to be evaluated more clearly.  Learn More

 

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Atelocollagen Neutral Solutions

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 Culture on collagen gel
  • Atelocollagen neutral solutions are adjusted to neutral pH and form a gel when they are warmed to 37°C. Learn More

 

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3D Honeycomb Boosted

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 3D Culture Cell transplantation
  • The honeycomb structure facilitates the access of nutrients to the cultured cells and the removal of waste products from the sponge, allowing cells to proliferate within the sponge.
  • It has high resilience to return to its original shape even after compression.
  • Cells are easily harvested by collagenase treatment.
  • It is biodegradable and suitable for cell transplantation.
  • It is immersed in PBS, eliminating the need for static electricity countermeasures and defoaming.  Learn More

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Atelocollagen, Honeycomb Sponge

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 3D Culture  Cell transplantation Sustained release carrier 
  • The honeycomb structure facilitates the access of nutrients to the cultured cells and the removal of waste products from the sponge, allowing cells to proliferate within the sponge.
  • Cells are easily harvested by collagenase treatment.
  • It is biodegradable and suitable for cell transplantation Learn More
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Atelocollagen Sponge, MIGHTY

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 3D Culture Mechanical stress culture Cell transplantation Sustained release carrier
       
  • Retains structural rigidity during repeated compressive loadings of 40 kPa.
  • Sized for 96-well plates.
  • It is biodegradable and suitable for cell transplantation  Learn More
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Atelocollagen Coated B-TCP Scaffold

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 Cell Culture  Cell transplantation Administration of osteogenic factors
  • Suitable for in vitro and in vivo bone formation studies with osteogenic factors.
  • Contains two types of discs: honeycomb-shaped discs and flat discs. Learn More
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Atelocollagen Microspheres

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 Mass-Culture
  • Collagen microspheres create an in vitro-like environment because they are produced exclusively from fibril-forming type I atelocollagen.
  • Cells are easily harvested by collagenase treatment.  Learn More
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Collagen Sponge for 35 mm Culture Dish

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 Cell Culture
  • This porous cross-linked sponge shaped scaffold is prepared from insoluble type I collagen derived from bovine Achilles tendon and is suitable for culturing cells. Learn More
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FibColl® Atelocollagen Inserts 24

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Culture on  the membrane Co-culture Cell sheet transplantation
  • Membranes made from atelocollagen are permeable to molecules with molecular weight even higher than 600 kDa.
  • A barrier function assessment model can be developed by tight junction formation of epithelial cells.
  • FibColl® is an easy-to-use hanging cell culture insert considering medium exchange and membrane recovery after culture.
  • The membrane is biodegradable and therefore it can also be used for cell sheet transplantation.  Learn More
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Atelocollagen, Permeable Membrane for 50 mm Culture Dish

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Culture on membrane Co-culture Cell sheet transplantation
  • Since the collagen membrane is fully permeable to small molecules, cells cultured on this membrane will maintain their polarity and absorb nutrients/excrete metabolic waste products across the membrane.
  • Because the membrane is transparent, microscopic observation of the cells is possible during culture.
  • Two different cell types can be cultured, one on each side of the membrane, and this membrane is particularly useful for cell-cell interaction studies without direct cell-cell contact. Learn More
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Atelocollagen, Permeable Membrane for 6-well, 24-well Culture Plate

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Culture on membrane Co-culture Cell sheet transplantation
  • Since the collagen membrane is fully permeable to small molecules, cells cultured on this membrane will maintain their polarity and absorb nutrients/excrete metabolic waste products across the membrane.
  • Because the membrane is transparent, microscopic observation of the cells is possible during culture.
  • Two different cell types can be cultured, one on each side of the membrane, and this membrane is particularly useful for cell-cell interaction studies without direct cell-cell contact.
  • It is biodegradable and suitable for cell sheet transplantation Learn More
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Type II Collagen

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Collagen coating Collagen induced arthritis model
  • High purity type II atelocollagen solution. Learn More
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Atelocollagen Powder, Membrane, Sponge

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Preparing high concentration solution Processing permeable membrane Cross-linking
  • High purity bovine dermis-derived atelocollagen powder, permeable membrane, and sponge for various research purposes. Useful for scaffold research. Learn More