Breast Milk Exosome
Recently, exosomes have been discovered in the milk of a variety of mammals, including human. It was shown that several exosome markers, such as CD63 and CD81, were also expressed in human breast milk. It has been reported that human breast milk contains many microRNAs, especially those involved in immunity. It was suggested that these exosomal microRNAs might be transferred from mother to infant through breast milk. It has been reported that immunocytes are regulated by exosomes present in human breast milk. It has also been reported that exosomes derived from pig breast milk exhibited a growth-stimulating effect directly upon infant intestinal epithelial cells. Because of these studies, the function and mechanisms of action of exosomes in breast milk have attracted considerable attention.
The raw breast milk has been confirmed by FDA-approved methods to be free of infection (HIV-1, HCV, HBV by NAT, HBsAg, HCV Ab, HIV 1 and 2 Ab, RPR).
Data
![](https://cdn11.bigcommerce.com/s-ydswqc5qsc/images/stencil/original/image-manager/milk-exosome01.png)
Using 0.5 μ g of protein as a sample, each protein was detected by western blot using Anti-CD9 monoclonal antibody (Cat. No. SHI-EXO-M01), AntiCD63 monoclonal antibody (Cat. No. SHI-EXO-M02), and Anti-CD81 monoclonal antibody (Cat. No. SHIEXO-M03).
![](https://cdn11.bigcommerce.com/s-ydswqc5qsc/images/stencil/original/image-manager/milk-exosome02.png)
The Breast Milk Exosome, Human (Cat. No. EXHM100L) was diluted x200 using PBS, then particle size distribution was measured using NanoSight LM10.
Mean particle size: 179nm
The number of particle in this product: 2.3 × 1012 Particles
*The number of exosome particles will be different between product-lot. Please consult with the CoA.
![](https://cdn11.bigcommerce.com/s-ydswqc5qsc/images/stencil/original/image-manager/milk-exosome03.png)
Product List
Breast Milk Exosome, Human
Product name | Catalog Number |
---|---|
Breast Milk exosome, Human | CSR-EXHM100L |
Anti-Human Tetraspanin Monoclonal Antibodies
Product name | Catalog Number |
---|---|
Anti CD9, Human (Mouse) Unlabeled, 12A12 | CAC-SHI-EXO-M01 |
Anti CD63, Human (Mouse) Unlabeled, 8A12 | CAC-SHI-EXO-M02 |
Anti CD81, Human (Mouse) Unlabeled, 12C4 | CAC-SHI-EXO-M03 |