Tetramer/APC - HLA-A*2402 WT1 (mutant) (CYTWNQMNL)

MBL

Catalog No: MBL-TS-M014-2

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The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.

Product Specifications

• Application: FC
• Reactivity: Human
• Conjugation: APC
• Peptide Sequence: CYTWNQMNL
• Class: Class I
• Sequence Location: 235-243
• MHC Allele: A*24:02

Citations for Tetramer/APC - HLA-A*2402 WT1 (mutant) (CYTWNQMNL) – 5 Found

Narita, Miwako; Masuko, Masayoshi; Kurasaki, Tohri; Kitajima, Toshiki; Takenouchi, Shoko; Saitoh, Anri; Watanabe, Norihiro; Furukawa, Tatsuo; Toba, Ken; Fuse, Ichiro; Aizawa, Yoshifusa; Kawakami, Manabu; Oka, Yoshihiro; Sugiyama, Haruo; Takahashi, Masuhiro. WT1 peptide vaccination in combination with imatinib therapy for a patient with CML in the chronic phase. International Journal Of Medical Sciences. 2010;7(2):72-81. 

Saitoh, Anri; Narita, Miwako; Watanabe, Norihiro; Tochiki, Nozomi; Yamahira, Akie; Nakamura, Takeshi; Kaji, Masami; Masuko, Masayoshi; Furukawa, Tatsuo; Toba, Ken; Fuse, Ichiro; Aizawa, Yoshifusa; Takahashi, Masuhiro. WT1 peptide vaccination in a CML patient: induction of effective cytotoxic T lymphocytes and significance of peptide administration interval. Medical Oncology (Northwood, London, England). 2011;28(1):219-30. 

Chiba, Yasuyoshi; Hashimoto, Naoya; Tsuboi, Akihiro; Oka, Yoshihiro; Murao, Ayako; Kinoshita, Manabu; Kagawa, Naoki; Oji, Yusuke; Hosen, Naoki; Nishida, Sumiyuki; Sugiyama, Haruo; Yoshimine, Toshiki. Effects of concomitant temozolomide and radiation therapies on WT1-specific T-cells in malignant glioma. Japanese Journal Of Clinical Oncology. 2010;40(5):395-403. 

Tsuboi, Akihiro; Oka, Yoshihiro; Nakajima, Hiroko; Fukuda, Yoko; Elisseeva, Olga A; Yoshihara, Satoshi; Hosen, Naoki; Ogata, Atsushi; Kito, Katsuyuki; Fujiki, Fumihiro; Nishida, Sumiyuki; Shirakata, Toshiaki; Ohno, Satoshi; Yasukawa, Masaki; Oji, Yusuke; Kawakami, Manabu; Morita, Satoshi; Sakamoto, Junichi; Udaka, Keiko; Kawase, Ichiro; Sugiyama, Haruo. Wilms tumor gene WT1 peptide-based immunotherapy induced a minimal response in a patient with advanced therapy-resistant multiple myeloma. International Journal Of Hematology. 2007;86(5):414-7. 

Lu, Xu; Liu, Jingwei; Cui, Peilin; Liu, Tao; Piao, Chunmei; Xu, Xianghong; Zhang, Qike; Xiao, Man; Liu, Xuesong; Wang, Yue; Yang, Lin. Co-inhibition of TIGIT, PD1, and Tim3 reverses dysfunction of Wilms tumor protein-1 (WT1)-specific CD8+ T lymphocytes after dendritic cell vaccination in gastric cancer. American Journal Of Cancer Research. 8(8):1564-1575.