MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases. Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.
| Product Specifications | |
| Application | FC |
| Reactivity | Mouse |
| Conjugation | PE |
| Citations for T-Select Mouse CD1d Tetramer-SA-PE – 10 Found |
| Yoshiga, Y; Goto, D; Segawa, S; Horikoshi, M; Hayashi, T; Matsumoto, I; Ito, S; Taniguchi, M; Sumida, T. Activation of natural killer T cells by α-carba-GalCer (RCAI-56), a novel synthetic glycolipid ligand, suppresses murine collagen-induced arthritis. Clinical And Experimental Immunology. 2011;164(2):236-47. PubMed |
| Horikoshi, Masanobu; Goto, Daisuke; Segawa, Seiji; Yoshiga, Yohei; Iwanami, Keiichi; Inoue, Asuka; Tanaka, Yuki; Matsumoto, Isao; Sumida, Takayuki. Activation of Invariant NKT cells with glycolipid ligand α-galactosylceramide ameliorates glucose-6-phosphate isomerase peptide-induced arthritis. Plos One. 7(12):e51215. PubMed |
| Sekiya, Takashi; Kashiwagi, Ikkou; Yoshida, Rei; Fukaya, Tomohiro; Morita, Rimpei; Kimura, Akihiro; Ichinose, Hiroshi; Metzger, Daniel; Chambon, Pierre; Yoshimura, Akihiko. Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis. Nature Immunology. 2013;14(3):230-7. PubMed |
| Nakamura, Takashi; Yamazaki, Daiki; Yamauchi, Jun; Harashima, Hideyoshi. The nanoparticulation by octaarginine-modified liposome improves α-galactosylceramide-mediated antitumor therapy via systemic administration. Journal Of Controlled Release : Official Journal Of The Controlled Release Society. 2013;171(2):216-24. PubMed |
| Adachi, Keishi; Nakamura, Risa; Osada, Yoshio; Senba, Masachika; Tamada, Koji; Hamano, Shinjiro. Involvement of IL-18 in the expansion of unique hepatic T cells with unconventional cytokine profiles during Schistosoma mansoni infection. Plos One. 9(5):e96042. PubMed |
| Shimamura, Michio; Yamamura, Masaki; Nabeshima, Tatsuya; Kitano, Naoki; van den Elzen, Peter; Yesilkaya, Hasan; Andrew, Peter; Illarionov, Petr. Activation of invariant natural killer T cells stimulated with microbial α-mannosyl glycolipids. Scientific Reports. 2017;7(1):9703. PubMed |
| Uchida, Takahiro; Nakashima, Hiroyuki; Yamagata, Akira; Ito, Seigo; Ishikiriyama, Takuya; Nakashima, Masahiro; Seki, Shuhji; Kumagai, Hiroo; Oshima, Naoki. Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice. Scientific Reports. 2018;8(1):8225. PubMed |
| Shimizu, Kanako; Sato, Yusuke; Kawamura, Masami; Nakazato, Hiroshi; Watanabe, Takashi; Ohara, Osamu; Fujii, Shin-Ichiro. Eomes transcription factor is required for the development and differentiation of invariant NKT cells. Communications Biology. 2:150. PubMed |
| Hojo, Miki Arai; Masuda, Kyoko; Hojo, Hiroaki; Nagahata, Yosuke; Yasuda, Keiko; Ohara, Daiya; Takeuchi, Yusuke; Hirota, Keiji; Suzuki, Yutaka; Kawamoto, Hiroshi; Kawaoka, Shinpei. Identification of a genomic enhancer that enforces proper apoptosis induction in thymic negative selection. Nature Communications. 2019;10(1):2603. PubMed - Comments: Used in: FCM |
| Komine-Aizawa, Shihoko; Ito, Shun; Aizawa, Shu; Namiki, Takahiro; Hayakawa, Satoshi. Cow milk exosomes activate NK cells and γδT cells in human PBMCs in vitro. Immunological Medicine. 2020;43(4):161-170. PubMed - Comments: Used in: FCM |
