The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.
| Product Specifications | |
| Application | FC |
| Reactivity | Human |
| Conjugation | PE |
| Peptide Sequence | PYKRIEELL |
| Citations for T-Select HLA-A*24:02 HTLV-1 Tax187-195 Tetramer-PYKRIEELL – 1 Found |
| Akimoto, Masaki; Kozako, Tomohiro; Sawada, Takashi; Matsushita, Kakushi; Ozaki, Atsuo; Hamada, Heiichiro; Kawada, Hideaki; Yoshimitsu, Makoto; Tokunaga, Masahito; Haraguchi, Koichi; Uozumi, Kimiharu; Arima, Naomichi; Tei, Chuwa. Anti-HTLV-1 tax antibody and tax-specific cytotoxic T lymphocyte are associated with a reduction in HTLV-1 proviral load in asymptomatic carriers. Journal Of Medical Virology. 2007;79(7):977-86. PubMed |