The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.
| Product Specifications | |
| Application | FC |
| Reactivity | Human |
| Conjugation | PE |
| Peptide Sequence | LFGYPVYVF |
| Citations for T-Select HLA-A*24:02 HTLV-1 Tax12-20 Tetramer-LFGYPVYVF – 1 Found |
| Sabouri, Amir H; Usuku, Koichiro; Hayashi, Daisuke; Izumo, Shuji; Ohara, Yoshiro; Osame, Mitsuhiro; Saito, Mineki. Impaired function of human T-lymphotropic virus type 1 (HTLV-1)-specific CD8+ T cells in HTLV-1-associated neurologic disease. Blood. 2008;112(6):2411-20. PubMed |