The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.
| Product Specifications | |
| Application | FC |
| Reactivity | Human |
| Conjugation | PE |
| Peptide Sequence | FFQFCPLIF |
| Citations for T-Select HLA-A*24:02 HTLV-1 Env11-19 Tetramer-FFQFCPLIF – 1 Found |
| Kozako, Tomohiro; Arima, Naomichi; Toji, Shingo; Masamoto, Izumi; Akimoto, Masaki; Hamada, Heiichiro; Che, Xiao-Fang; Fujiwara, Hiroshi; Matsushita, Kakushi; Tokunaga, Masahito; Haraguchi, Koichi; Uozumi, Kimiharu; Suzuki, Susumu; Takezaki, Toshiro; Sonoda, Shunro. Reduced frequency, diversity, and function of human T cell leukemia virus type 1-specific CD8+ T cell in adult T cell leukemia patients. Journal Of Immunology (Baltimore, Md. : 1950). 2006;177(8):5718-26. PubMed |