The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.
| Product Specifications | |
| Application | FC |
| Reactivity | Human |
| Conjugation | PE |
| Peptide Sequence | QLGAFLTNV |
| Citations for T-Select HLA-A*02:01 HTLV-1 Tax178-186 Tetramer-QLGAFLTNV – 1 Found |
| Tanaka, Yukie; Nakasone, Hideki; Yamazaki, Rie; Sato, Ken; Sato, Miki; Terasako, Kiriko; Kimura, Shun-ichi; Okuda, Shinya; Kako, Shinichi; Oshima, Kumi; Tanihara, Aki; Nishida, Junji; Yoshikawa, Toshiaki; Nakatsura, Tetsuya; Sugiyama, Haruo; Kanda, Yoshinobu. Single-cell analysis of T-cell receptor repertoire of HTLV-1 Tax-specific cytotoxic T cells in allogeneic transplant recipients with adult T-cell leukemia/lymphoma. Cancer Research. 2010;70(15):6181-92. PubMed |