Recombinant Human IL-18 (without BSA)

Catalog No:
MBL-B003-5

Availability: 12PM PT on Dec. 3, 2024

IL-18 Protein of 25 µg.

Product Specifications
Gene ID - Human

10068

Molecular Weight 18 kDa
Purity Greater than 90% purity as confirmed on SDS-PAGE by Coomassie brilliant blue staining
Formulation 25 μg in 250 μl volume of PBS containing 1% sucrose.

Citations for Recombinant Human IL-18 (without BSA) – 10 Found
Guia, Sophie; Cognet, Céline; de Beaucoudrey, Ludovic; Tessmer, Marlowe S; Jouanguy, Emmanuelle; Berger, Claire; Filipe-Santos, Orchidée; Feinberg, Jacqueline; Camcioglu, Yildiz; Levy, Jacob; Al Jumaah, Suliman; Al-Hajjar, Sami; Stephan, Jean-Louis; Fieschi, Claire; Abel, Laurent; Brossay, Laurent; Casanova, Jean-Laurent; Vivier, Eric. A role for interleukin-12/23 in the maturation of human natural killer and CD56+ T cells in vivo. Blood. 2008;111(10):5008-16.  PubMed
Takei, Satoko; Hoshino, Tomoaki; Matsunaga, Kazuko; Sakazaki, Yuki; Sawada, Masanori; Oda, Hanako; Takenaka, Shin-ichi; Imaoka, Haruki; Kinoshita, Takashi; Honda, Seiyo; Ida, Hiroaki; Fukuda, Taka-aki; Aizawa, Hisamichi. Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis. Arthritis Research & Therapy. 2011;13(2):R52.  PubMed
Reichwald, Kirsten; Jørgensen, Tina Z; Tougaard, Peter; Skov, Søren. TL1A induces TCR independent IL-6 and TNF-α production and growth of PLZF⁺ leukocytes. Plos One. 9(1):e85793.  PubMed
Reichwald, Kirsten; Jørgensen, Tina Z; Skov, Søren. TL1A increases expression of CD25, LFA-1, CD134 and CD154, and induces IL-22 and GM-CSF production from effector CD4 T-cells. Plos One. 9(8):e105627.  PubMed
Ijima, Ryo; Kaneko, Hiroki; Ye, Fuxiang; Nagasaka, Yosuke; Takayama, Kei; Kataoka, Keiko; Kachi, Shu; Iwase, Takeshi; Terasaki, Hiroko. Interleukin-18 induces retinal pigment epithelium degeneration in mice. Investigative Ophthalmology & Visual Science. 2014;55(10):6673-8.  PubMed
Guerville, Florent; Daburon, Sophie; Marlin, Romain; Lartigue, Lydia; Loizon, Severine; Pitard, Vincent; Couzi, Lionel; Moreau, Jean-François; Déchanet-Merville, Julie; Faustin, Benjamin. TCR-dependent sensitization of human γδ T cells to non-myeloid IL-18 in cytomegalovirus and tumor stress surveillance. Oncoimmunology. 2015;4(5):e1003011.  PubMed
Molgora, Martina; Bonavita, Eduardo; Ponzetta, Andrea; Riva, Federica; Barbagallo, Marialuisa; Jaillon, Sébastien; Popović, Branka; Bernardini, Giovanni; Magrini, Elena; Gianni, Francesca; Zelenay, Santiago; Jonjić, Stipan; Santoni, Angela; Garlanda, Cecilia; Mantovani, Alberto. IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity. Nature. 2017;551(7678):110-114.  PubMed
Tanaka, Yoshitaka; Nakazawa, Tsutomu; Nakamura, Mitsutoshi; Nishimura, Fumihiko; Matsuda, Ryosuke; Omoto, Koji; Shida, Yoichi; Murakami, Toshiharu; Nakagawa, Ichiro; Motoyama, Yasushi; Morita, Hiromichi; Tsujimura, Takahiro; Nakase, Hiroyuki. Ex vivo-expanded highly purified natural killer cells in combination with temozolomide induce antitumor effects in human glioblastoma cells in vitro. Plos One. 14(3):e0212455.  PubMed
Ambegaonkar, Abhijit A; Nagata, Satoshi; Pierce, Susan K; Sohn, Haewon. The Differentiation in vitro of Human Tonsil B Cells With the Phenotypic and Functional Characteristics of T-bet+ Atypical Memory B Cells in Malaria. Frontiers In Immunology. 10:852.  PubMed
Comments: Used in: Function
Stiglund, Natalie; Strand, Kristina; Cornillet, Martin; Stål, Per; Thorell, Anders; Zimmer, Christine L; Näslund, Erik; Karlgren, Silja; Nilsson, Henrik; Mellgren, Gunnar; Fernø, Johan; Hagström, Hannes; Björkström, Niklas K. Retained NK Cell Phenotype and Functionality in Non-alcoholic Fatty Liver Disease. Frontiers In Immunology. 10:1255.  PubMed
Comments: Used in: Function