MHC Tetramers are used for the detection of antigen-specific T-cell populations. MHC-peptide tetramer complexes recognize antigen specific T-cells at the single cell level, allowing for accurate measurements of the functional immune response in cancer, infectious diseases, and autoimmune diseases. Due to their increased avidity, MHC tetramers stably bind to cognate TcRs and are evaluated using flow cytometry.
| Product Specifications | |
| Application | FC |
| Reactivity | Monkey |
| Conjugation | APC |
| Peptide Sequence | SSVDEQIQW |
| Citations for Mamu-A*90120-5 SIV gag Tetramer-SSVDEQIQW-APC – 1 Found |
| Tsukamoto, Tetsuo; Takeda, Akiko; Yamamoto, Takuya; Yamamoto, Hiroyuki; Kawada, Miki; Matano, Tetsuro. Impact of cytotoxic-T-lymphocyte memory induction without virus-specific CD4+ T-Cell help on control of a simian immunodeficiency virus challenge in rhesus macaques. Journal Of Virology. 2009;83(18):9339-46. PubMed |
