The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.
| Product Specifications | |
| Application | FC |
| Reactivity | Human |
| Conjugation | PE |
| Peptide Sequence | QYDPVAALF |
| Citations for iTAg Tetramer/PE - HLA-A*24:02 CMV (QYDPVAALF) – 1 Found |
| Watanabe, Kazue; Suzuki, Susumu; Kamei, Michi; Toji, Shingo; Kawase, Takakazu; Takahashi, Toshitada; Kuzushima, Kiyotaka; Akatsuka, Yoshiki. CD137-guided isolation and expansion of antigen-specific CD8 cells for potential use in adoptive immunotherapy. International Journal Of Hematology. 2008;88(3):311-320. PubMed |