HLA-A*24:02 Survivin-2B Tetramer-AYACNTSTL-PE

Catalog No:
MBL-TS-M025-1

Availability: 12PM PT on Dec. 3, 2024

The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.

Product Specifications
Application FC
Reactivity Human
Conjugation PE
Peptide Sequence AYACNTSTL

Citations for HLA-A*24:02 Survivin-2B Tetramer-AYACNTSTL-PE – 6 Found
Kameshima, Hidekazu; Tsuruma, Tetsuhiro; Torigoe, Toshihiko; Takahashi, Akari; Hirohashi, Yoshihiko; Tamura, Yasuaki; Tsukahara, Tomohide; Ichimiya, Shingo; Kanaseki, Takayuki; Iwayama, Yuji; Sato, Noriyuki; Hirata, Koichi. Immunogenic enhancement and clinical effect by type-I interferon of anti-apoptotic protein, survivin-derived peptide vaccine, in advanced colorectal cancer patients. Cancer Science. 2011;102(6):1181-7.  PubMed
Miyazaki, Akihiro; Kobayashi, Junichi; Torigoe, Toshihiko; Hirohashi, Yoshihiko; Yamamoto, Takashi; Yamaguchi, Akira; Asanuma, Hiroko; Takahashi, Akari; Michifuri, Yoshitaka; Nakamori, Kenji; Nagai, Itaru; Sato, Noriyuki; Hiratsuka, Hiroyoshi. Phase I clinical trial of survivin-derived peptide vaccine therapy for patients with advanced or recurrent oral cancer. Cancer Science. 2011;102(2):324-9.  PubMed
Shima, Hiroaki; Kutomi, Goro; Satomi, Fukino; Imamura, Masafumi; Kimura, Yasutoshi; Mizuguchi, Toru; Watanabe, Kazue; Takahashi, Akari; Murai, Aiko; Tsukahara, Tomohide; Kanaseki, Takayuki; Hirohashi, Yoshihiko; Iwayama, Yuji; Tsuruma, Tetsuhiro; Kameshima, Hidekazu; Sato, Noriyuki; Torigoe, Toshihiko; Takemasa, Ichiro. Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine. Cancer Immunology, Immunotherapy : Cii. 2018;67(10):1603-1609.  PubMed
Shibayama, Yuji; Tsukahara, Tomohide; Emori, Makoto; Murata, Kenji; Mizushima, Emi; Hirohashi, Yoshihiko; Kanaseki, Takayuki; Nakatsugawa, Munehide; Kubo, Terufumi; Yamashita, Toshihiko; Sato, Noriyuki; Torigoe, Toshihiko. Implication of chemo-resistant memory T cells for immune surveillance in patients with sarcoma receiving chemotherapy. Cancer Science. 2017;108(9):1739-1745.  PubMed
Watanabe, Kazue; Tsukahara, Tomohide; Toji, Shingo; Saitoh, Shogo; Hirohashi, Yoshihiko; Nakatsugawa, Munehide; Kubo, Terufumi; Kanaseki, Takayuki; Kameshima, Hidekazu; Terui, Takeshi; Sato, Noriyuki; Torigoe, Toshihiko. Development of a T-cell receptor multimer with high avidity for detecting a naturally presented tumor-associated antigen on osteosarcoma cells. Cancer Science. 2019;110(1):40-51.  PubMed
Kurosawa, Nobuyuki; Wakata, Yuka; Ida, Kenta; Midorikawa, Aki; Isobe, Masaharu. High throughput development of TCR-mimic antibody that targets survivin-2B(80-88)/HLA-A*A24 and its application in a bispecific T-cell engager. Scientific Reports. 2019;9(1):9827.  PubMed