CycLex® CaM-kinase II assay kit

Catalog No:
MBL-CY-1173

Availability: 12PM PT on Dec. 3, 2024

The CycLex CaM kinase II Assay Kit is primarily designed to measure the activities of purified Ca2+/Calmodulin dependent protein kinase II (CaM kinase II) for the rapid and sensitive evaluation of inhibitors or activators. It can be used for 96 assays.

Product Specifications
Application ELISA

Citations for CycLex® CaM-kinase II assay kit – 16 Found
Stack, Edward C; Desarnaud, Frank; Siwek, Donald F; Datta, Subimal. A novel role for calcium/calmodulin kinase II within the brainstem pedunculopontine tegmentum for the regulation of wakefulness and rapid eye movement sleep. Journal Of Neurochemistry. 2010;112(1):271-81.  PubMed
Yang, Yoo Jung; Lee, Hak Ju; Lee, Byung Koo; Lim, Sung Cil; Lee, Chong Kil; Lee, Myung Koo. Effects of scoparone on dopamine release in PC12 cells. Fitoterapia. 2010;81(6):497-502.  PubMed
Bodhinathan, Karthik; Kumar, Ashok; Foster, Thomas C. Intracellular redox state alters NMDA receptor response during aging through Ca2+/calmodulin-dependent protein kinase II. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience. 2010;30(5):1914-24.  PubMed
Shahin, Rand; Taha, Mutasem O. Elaborate ligand-based modeling and subsequent synthetic exploration unveil new nanomolar Ca2+/calmodulin-dependent protein kinase II inhibitory leads. Bioorganic & Medicinal Chemistry. 2012;20(1):377-400.  PubMed
Hamdani, Nazha; Krysiak, Judith; Kreusser, Michael M; Neef, Stefan; Dos Remedios, Cristobal G; Maier, Lars S; Krüger, Markus; Backs, Johannes; Linke, Wolfgang A. Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation. Circulation Research. 2013;112(4):664-74.  PubMed
Lu, Qing; Harris, Valerie A; Sun, Xutong; Hou, Yali; Black, Stephen M. Ca²⁺/calmodulin-dependent protein kinase II contributes to hypoxic ischemic cell death in neonatal hippocampal slice cultures. Plos One. 8(8):e70750.  PubMed
Wang, Ning; Chen, Linlin; Cheng, Nan; Zhang, Jingyun; Tian, Tian; Lu, Wei. Active calcium/calmodulin-dependent protein kinase II (CaMKII) regulates NMDA receptor mediated postischemic long-term potentiation (i-LTP) by promoting the interaction between CaMKII and NMDA receptors in ischemia. Neural Plasticity. 2014:827161.  PubMed
Chen, Liang; Miao, Yanyan; Chen, Lin; Xu, Jing; Wang, Xinxing; Zhao, Han; Shen, Yi; Hu, Yi; Bian, Yunpeng; Shen, Yuanyuan; Chen, Jutao; Zha, Yingying; Wen, Long-Ping; Wang, Ming. The role of low levels of fullerene C60 nanocrystals on enhanced learning and memory of rats through persistent CaMKII activation. Biomaterials. 2014;35(34):9269-79.  PubMed
Park, Chan Jin; Song, Sang Ha; Kim, Dae Han; Gye, Myung Chan. Nickel affects gill and muscle development in oriental fire-bellied toad (Bombina orientalis) embryos. Aquatic Toxicology (Amsterdam, Netherlands). 2017;182:67-78.  PubMed
Van Linthout, Sophie; Hamdani, Nazha; Miteva, Kapka; Koschel, Annika; Müller, Irene; Pinzur, Lena; Aberman, Zami; Pappritz, Kathleen; Linke, Wolfgang Albrecht; Tschöpe, Carsten. Placenta-Derived Adherent Stromal Cells Improve Diabetes Mellitus-Associated Left Ventricular Diastolic Performance. Stem Cells Translational Medicine. 2017;6(12):2135-2145.  PubMed
Miura, Masahito; Handoh, Tetsuya; Taguchi, Yuhto; Hasegawa, Taiki; Takahashi, Yui; Morita, Natsuki; Matsumoto, Ayana; Shindoh, Chiyohiko; Sato, Haruka. Transient Elevation of Glucose Increases Arrhythmia Susceptibility in Non-Diabetic Rat Trabeculae With Non-Uniform Contraction. Circulation Journal : Official Journal Of The Japanese Circulation Society. 2020;84(4):551-558.  PubMed
Herwig, Melissa; Kolijn, Detmar; Lódi, Mária; Hölper, Soraya; Kovács, Árpád; Papp, Zoltán; Jaquet, Kornelia; Haldenwang, Peter; Dos Remedios, Cris; Reusch, Peter H; Mügge, Andreas; Krüger, Marcus; Fielitz, Jens; Linke, Wolfgang A; Hamdani, Nazha. Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D. Frontiers In Physiology. 11:240.  PubMed
Kolijn, Detmar; Kovács, Árpád; Herwig, Melissa; Lódi, Mária; Sieme, Marcel; Alhaj, Abdulatif; Sandner, Peter; Papp, Zoltán; Reusch, Peter H; Haldenwang, Peter; Falcão-Pires, Ines; Linke, Wolfgang A; Jaquet, Kornelia; Van Linthout, Sophie; Mügge, Andreas; Tschöpe, Carsten; Hamdani, Nazha. Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator. Frontiers In Physiology. 11:345.  PubMed
Nawaratna, Sujeevi S K; McManus, Donald P; Gasser, Robin B; Brindley, Paul J; Boyle, Glen M; Rivera, Vanessa; Ranasinghe, Shiwanthi L; Jones, Malcolm K; You, Hong; Gobert, Geoffrey N. Use of kinase inhibitors against schistosomes to improve and broaden praziquantel efficacy. Parasitology. 2020;147(13):1488-1498.  PubMed
Ma, Yanzhuo; Cheng, Nancy; Sun, Junping; Lu, Jonathan Xuhai; Abbasi, Shahrzad; Wu, Geru; Lee, An-Sheng; Sawamura, Tatsuya; Cheng, Jie; Chen, Chu-Huang; Xi, Yutao. Atherogenic L5 LDL induces cardiomyocyte apoptosis and inhibits K(ATP) channels through CaMKII activation. Lipids In Health And Disease. 2020;19(1):189.  PubMed
Comments: Used in: ELISA
Miura, Masahito; Hasegawa, Taiki; Matsumoto, Ayana; Nishiyama, Masami; Someya, Yuka; Satoh, Wakako; Kumasaka, Kazunori; Shindoh, Chiyohiko; Sato, Haruka. Effect of transient elevation of glucose on contractile properties in non-diabetic rat cardiac muscle. Heart And Vessels. 2021;36(4):568-576.  PubMed