The CycLex Research Product CircuLex PCSK9-LDLR in vitro Binding Assay Kit can be used for screening inhibitors of PCSK9-LDLR interaction in vitro.
| Product Specifications | |
| Application | ELISA |
| Citations for CircuLex PCSK9-LDLR in vitro Binding Assay Kit – 3 Found |
| Lammi, Carmen; Zanoni, Chiara; Aiello, Gilda; Arnoldi, Anna; Grazioso, Giovanni. Lupin Peptides Modulate the Protein-Protein Interaction of PCSK9 with the Low Density Lipoprotein Receptor in HepG2 Cells. Scientific Reports. 2016;6:29931. PubMed |
| Lammi, Carmen; Sgrignani, Jacopo; Arnoldi, Anna; Grazioso, Giovanni. Biological Characterization of Computationally Designed Analogs of peptide TVFTSWEEYLDWV (Pep2-8) with Increased PCSK9 Antagonistic Activity. Scientific Reports. 2019;9(1):2343. PubMed |
| Evison, Benny J; Palmer, James T; Lambert, Gilles; Treutlein, Herbert; Zeng, Jun; Nativel, Brice; Chemello, Kévin; Zhu, Qing; Wang, Jie; Teng, Yanfen; Tang, Wei; Xu, Yanfeng; Rathi, Anuj Kumar; Kumar, Sanjay; Suchowerska, Alexandra K; Parmar, Jasneet; Dixon, Ian; Kelly, Graham E; Bonnar, James. A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove. Bioorganic & Medicinal Chemistry. 2020;28(6):115344. PubMed |