CircuLex PCSK9 D374Y (His-tagged)

MBL

Catalog No: MBL-CY-R2331

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CircuLex PCSK9 D374Y (His-tagged) of 10 µg and The PCSK9 D374Y demonstrates 64 kDa (catalytic and C-terminal domain) and 16 kDa (prodomain band) by SDS-PAGE analysis.

Product Specifications

• Gene ID - Human:

  255738

• Gene ID - Mouse:

  100102

• Purity: The PCSK9 D374Y is greater than 95% pure as determined by SDS-PAGE analysis.
• Formulation: The PCSK9 D374Y is supplied frozen in PBS pH 7.2, 10 % glycerol.

Citations for CircuLex PCSK9 D374Y (His-tagged) – 1 Found

Evison, Benny J; Palmer, James T; Lambert, Gilles; Treutlein, Herbert; Zeng, Jun; Nativel, Brice; Chemello, Kévin; Zhu, Qing; Wang, Jie; Teng, Yanfen; Tang, Wei; Xu, Yanfeng; Rathi, Anuj Kumar; Kumar, Sanjay; Suchowerska, Alexandra K; Parmar, Jasneet; Dixon, Ian; Kelly, Graham E; Bonnar, James. A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove. Bioorganic & Medicinal Chemistry. 2020;28(6):115344.