CircuLex PCSK9 D374Y (His-tagged) of 10 µg and The PCSK9 D374Y demonstrates 64 kDa (catalytic and C-terminal domain) and 16 kDa (prodomain band) by SDS-PAGE analysis.
| Product Specifications |
| Gene ID - Human |
255738 |
| Gene ID - Mouse |
100102 |
| Purity |
The PCSK9 D374Y is greater than 95% pure as determined by SDS-PAGE analysis. |
| Formulation |
The PCSK9 D374Y is supplied frozen in PBS pH 7.2, 10 % glycerol. |
| Storage |
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| Citations for CircuLex PCSK9 D374Y (His-tagged) – 1 Found |
| Evison, Benny J; Palmer, James T; Lambert, Gilles; Treutlein, Herbert; Zeng, Jun; Nativel, Brice; Chemello, Kévin; Zhu, Qing; Wang, Jie; Teng, Yanfen; Tang, Wei; Xu, Yanfeng; Rathi, Anuj Kumar; Kumar, Sanjay; Suchowerska, Alexandra K; Parmar, Jasneet; Dixon, Ian; Kelly, Graham E; Bonnar, James. A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove. Bioorganic & Medicinal Chemistry. 2020;28(6):115344. PubMed |
